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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3320 | 2009 |
TREM2 variants in Alzheimer's disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013 | 3115 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2262 | 2019 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2188 | 2011 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2162 | 2011 |
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ... Science translational medicine 3 (89), 89ra57-89ra57, 2011 | 1404 | 2011 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1390 | 2018 |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ... Nature genetics 50 (4), 524-537, 2018 | 1279 | 2018 |
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ... Nature 549 (7673), 523-527, 2017 | 1008 | 2017 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 921 | 2017 |
OASIS-3: longitudinal neuroimaging, clinical, and cognitive dataset for normal aging and Alzheimer disease PJ LaMontagne, TLS Benzinger, JC Morris, S Keefe, R Hornbeck, ... MedRxiv, 2019.12. 13.19014902, 2019 | 606 | 2019 |
Alzheimer’s disease genetics: from the bench to the clinic CM Karch, C Cruchaga, AM Goate Neuron 83 (1), 11-26, 2014 | 529 | 2014 |
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014 | 528 | 2014 |
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ... PloS one 5 (11), e13950, 2010 | 451 | 2010 |
Common polygenic variation enhances risk prediction for Alzheimer’s disease V Escott-Price, R Sims, C Bannister, D Harold, M Vronskaya, E Majounie, ... Brain 138 (12), 3673-3684, 2015 | 427 | 2015 |
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... Nature genetics 44 (12), 1349-1354, 2012 | 402 | 2012 |
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014 | 387 | 2014 |
Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families C Cruchaga, S Chakraverty, K Mayo, FLM Vallania, RD Mitra, K Faber, ... PloS one 7 (2), e31039, 2012 | 387 | 2012 |
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 385 | 2013 |