| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1410 | 2018 |
| The immunomodulatory metabolite itaconate modifies NLRP3 and inhibits inflammasome activation A Hooftman, S Angiari, S Hester, SE Corcoran, MC Runtsch, C Ling, ... Cell metabolism 32 (3), 468-478. e7, 2020 | 375 | 2020 |
| Metabolic regulation of nlrp 3 MM Hughes, LAJ O'Neill Immunological reviews 281 (1), 88-98, 2018 | 272 | 2018 |
| Glutathione transferase omega-1 regulates NLRP3 inflammasome activation through NEK7 deglutathionylation MM Hughes, A Hooftman, S Angiari, P Tummala, Z Zaslona, MC Runtsch, ... Cell reports 29 (1), 151-161. e5, 2019 | 74 | 2019 |
| Caspase-11 promotes allergic airway inflammation Z Zasłona, E Flis, MM Wilk, RG Carroll, EM Palsson-McDermott, ... Nature Communications 11 (1), 1055, 2020 | 67 | 2020 |
| Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis JDG Leach, N Vlahov, P Tsantoulis, RA Ridgway, DJ Flanagan, K Gilroy, ... Nature communications 12 (1), 3464, 2021 | 52 | 2021 |
| A common variant in the adaptor mal regulates interferon gamma signaling CN Cheallaigh, FJ Sheedy, J Harris, N Munoz-Wolf, J Lee, K West, ... Immunity 44 (2), 368-379, 2016 | 43 | 2016 |
| Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling MM Hughes, P Lavrencic, RC Coll, T Ve, DG Ryan, NC Williams, ... Proceedings of the National Academy of Sciences 114 (32), E6480-E6489, 2017 | 40 | 2017 |
| Studies on the Mechanism of Pathogenicity of Neisseria Gonorrhoeae P Novotny, JA Short, M Hughes, JJ Miler, C Syrett, WH Turner, JRW Harris, ... Journal of Medical Microbiology 10 (3), 347-366, 1977 | 37 | 1977 |
| Glutathione and glutathione transferase omega 1 as key posttranslational regulators in macrophages MM Hughes, AF McGettrick, LAJ O’Neill Microbiology spectrum 5 (1), 10.1128/microbiolspec. mchd-0044-2016, 2017 | 26 | 2017 |
| Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target J Vande Voorde, RT Steven, AK Najumudeen, CA Ford, A Dexter, ... Nature metabolism 5 (8), 1303-1318, 2023 | 17 | 2023 |
| Strain related infectivity of Neisseria gonorrhoeae for the guinea-pig subcutaneous chamber and the variability of the immune resistance in different breeds of guinea-pig. P Novotny, ES Broughton, K Cownley, M Hughes, WH Turner Sexually Transmitted Infections 54 (2), 88-96, 1978 | 10 | 1978 |
| The gender gap in European neurosurgical conference presentations J Woodfield, PC Copley, M Hughes, E Edlmann Neurosurgical focus 50 (3), E7, 2021 | 8 | 2021 |
| Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation P Tummala, M Rooke, JE Dahlstrom, S Takahashi, MG Casarotto, ... Carcinogenesis 42 (6), 853-863, 2021 | 4 | 2021 |
| Finite group actions on homotopy complex projective spaces M Hughes Mathematische Zeitschrift 199, 133-151, 1988 | 4 | 1988 |
| Vale Bruce Lord R Pockett, M Hughes Australian Social Work 69 (3), 255-256, 2016 | 3 | 2016 |
| Symmetries of homotopy complex projective three spaces M Hughes Transactions of the American Mathematical Society 337 (1), 291-304, 1993 | 3 | 1993 |
| Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function A Santi, EJ Kay, LJ Neilson, L McGarry, S Lilla, M Mullin, NR Paul, ... Science Signaling 17 (827), eade0580, 2024 | 2 | 2024 |
| Microsatellite variation and genetic conservation in British sheep breeds M Hughes PQDT-UK & Ireland, 1999 | 1 | 1999 |
| Dihedral group actions on homotopy complex projective three spaces M Hughes Pacific Journal of Mathematics 150 (1), 97-110, 1991 | 1 | 1991 |
