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Erik Storkebaum
Erik Storkebaum
Professor of Molecular Neurobiology, Donders Institute and Radboud University
在 donders.ru.nl 的电子邮件经过验证 - 首页
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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
B Oosthuyse, L Moons, E Storkebaum, H Beck, D Nuyens, K Brusselmans, ...
Nature genetics 28 (2), 131-138, 2001
13472001
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
D Lambrechts, E Storkebaum, M Morimoto, J Del-Favero, F Desmet, ...
Nature genetics 34 (4), 383-394, 2003
11032003
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
M Azzouz, GS Ralph, E Storkebaum, LE Walmsley, KA Mitrophanous, ...
Nature 429 (6990), 413-417, 2004
7832004
VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
E Storkebaum, D Lambrechts, P Carmeliet
Bioessays 26 (9), 943-954, 2004
6872004
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ...
Nature neuroscience 8 (1), 85-92, 2005
6142005
VEGF: a critical player in neurodegeneration
E Storkebaum, P Carmeliet
The Journal of clinical investigation 113 (1), 14-18, 2004
4162004
Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders
P Carmeliet, E Storkebaum
Seminars in cell & developmental biology 13 (1), 39-53, 2002
3412002
Vascular endothelial growth factor: a neurovascular target in neurological diseases
C Lange, E Storkebaum, CR De Almodóvar, M Dewerchin, P Carmeliet
Nature Reviews Neurology 12 (8), 439-454, 2016
3142016
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, ...
Nature communications 9 (1), 335, 2018
2312018
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
J Scekic‐Zahirovic, O Sendscheid, H El Oussini, M Jambeau, Y Sun, ...
The EMBO journal 35 (10), 1077-1097, 2016
2152016
Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E–deficient mice
A Luttun, F Lupu, E Storkebaum, MF Hoylaerts, L Moons, J Crawley, ...
Arteriosclerosis, thrombosis, and vascular biology 22 (3), 499-505, 2002
1522002
Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration
L Van Den Bosch, E Storkebaum, V Vleminckx, L Moons, ...
Neurobiology of disease 17 (1), 21-28, 2004
1442004
Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases
S Niehues, J Bussmann, G Steffes, I Erdmann, C Köhrer, L Sun, ...
Nature communications 6 (1), 7520, 2015
1232015
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot–Marie–Tooth neuropathy
E Storkebaum, R Leitão-Gonçalves, T Godenschwege, L Nangle, M Mejia, ...
Proceedings of the National Academy of Sciences 106 (28), 11782-11787, 2009
1232009
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis
J Scekic-Zahirovic, HE Oussini, S Mersmann, K Drenner, M Wagner, ...
Acta neuropathologica 133, 887-906, 2017
1212017
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
TG Moens, T Niccoli, KM Wilson, ML Atilano, N Birsa, LM Gittings, ...
Acta Neuropathologica 137, 487-500, 2019
1062019
Cerebrovascular disorders: molecular insights and therapeutic opportunities
E Storkebaum, A Quaegebeur, M Vikkula, P Carmeliet
Nature neuroscience 14 (11), 1390-1397, 2011
1022011
FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis
G Picchiarelli, M Demestre, A Zuko, M Been, J Higelin, S Dieterlé, MA Goy, ...
Nature neuroscience 22 (11), 1793-1805, 2019
922019
Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1
CR De Almodovar, C Coulon, PA Salin, E Knevels, N Chounlamountri, ...
Journal of Neuroscience 30 (45), 15052-15066, 2010
902010
Cell-selective labelling of proteomes in Drosophila melanogaster
I Erdmann, K Marter, O Kobler, S Niehues, J Abele, A Müller, J Bussmann, ...
Nature communications 6 (1), 7521, 2015
892015
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