Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature DT Grimes, CW Boswell, NFC Morante, RM Henkelman, RD Burdine, ... Science 352 (6291), 1341-1344, 2016 | 267 | 2016 |
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2 S Field, KL Riley, DT Grimes, H Hilton, M Simon, N Powles-Glover, ... Development 138 (6), 1131-1142, 2011 | 209 | 2011 |
Left–right patterning: breaking symmetry to asymmetric morphogenesis DT Grimes, RD Burdine Trends in Genetics 33 (9), 616-628, 2017 | 126 | 2017 |
Mouse models of ciliopathies: the state of the art DP Norris, DT Grimes Disease models & mechanisms 5 (3), 299-312, 2012 | 113 | 2012 |
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of … VL Patterson, C Damrau, A Paudyal, B Reeve, DT Grimes, ME Stewart, ... Human molecular genetics 18 (10), 1719-1739, 2009 | 100 | 2009 |
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling A Harris, P Siggers, S Corrochano, N Warr, D Sagar, DT Grimes, M Suzuki, ... Proceedings of the National Academy of Sciences 115 (21), 5474-5479, 2018 | 81 | 2018 |
c21orf59/kurly controls both cilia motility and polarization KM Jaffe, DT Grimes, J Schottenfeld-Roames, ME Werner, TSJ Ku, ... Cell reports 14 (8), 1841-1849, 2016 | 80 | 2016 |
Genetic analysis reveals a hierarchy of interactions between polycystin-encoding genes and genes controlling cilia function during left-right determination DT Grimes, JL Keynton, MT Buenavista, X Jin, SH Patel, S Kyosuke, ... PLoS genetics 12 (6), e1006070, 2016 | 68 | 2016 |
Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model RV Walker, JL Keynton, DT Grimes, V Sreekumar, DJ Williams, C Esapa, ... Nature communications 10 (1), 4072, 2019 | 55 | 2019 |
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis P Goggolidou, J L. Stevens, F Agueci, J Keynton, G Wheway, DT Grimes, ... Development 141 (20), 3966-3977, 2014 | 48 | 2014 |
Modeling syndromic congenital heart defects in zebrafish MG Grant, VL Patterson, DT Grimes, RD Burdine Current topics in developmental biology 124, 1-40, 2017 | 46 | 2017 |
Making and breaking symmetry in development, growth and disease DT Grimes Development 146 (16), dev170985, 2019 | 38 | 2019 |
Cilia discern left from right DP Norris, DT Grimes Science 338 (6104), 206-207, 2012 | 30 | 2012 |
On being the right shape: Roles for motile cilia and cerebrospinal fluid flow in body and spine morphology EA Bearce, DT Grimes Seminars in Cell & Developmental Biology 110, 104-112, 2021 | 26 | 2021 |
Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish DT Grimes, VL Patterson, G Luna-Arvizu, J Schottenfeld-Roames, ... Developmental biology 459 (2), 79-86, 2020 | 23 | 2020 |
Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology EA Bearce, ZH Irons, JR O'Hara-Smith, CJ Kuhns, SI Fisher, WE Crow, ... Elife 11, e83883, 2022 | 14 | 2022 |
Antagonistic interactions in the zebrafish midline prior to the emergence of asymmetric gene expression are important for left–right patterning RD Burdine, DT Grimes Philosophical Transactions of the Royal Society B: Biological Sciences 371 …, 2016 | 13 | 2016 |
Developmental biology: go with the flow to keep the body straight DT Grimes Current Biology 29 (3), R101-R103, 2019 | 11 | 2019 |
Daw1 regulates the timely onset of cilia motility during development EA Bearce, ZH Irons, SB Craig, CJ Kuhns, C Sabazali, DR Farnsworth, ... Development 149 (12), dev200017, 2022 | 7 | 2022 |
Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities JS Leslie, R Hjeij, A Vivante, EA Bearce, L Dyer, J Wang, L Rawlins, ... Genetics in Medicine 24 (11), 2249-2261, 2022 | 4 | 2022 |