Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction JC Regan, M Khericha, AJ Dobson, E Bolukbasi, N Rattanavirotkul, ... elife 5, e10956, 2016 | 214 | 2016 |
Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality ML Concha, C Russell, JC Regan, M Tawk, S Sidi, DT Gilmour, ... Neuron 39 (3), 423-438, 2003 | 208 | 2003 |
Gender and longevity: why do men die earlier than women? Comparative and experimental evidence JC Regan, L Partridge Best practice & research Clinical endocrinology & metabolism 27 (4), 467-479, 2013 | 167 | 2013 |
Steroid Hormone Signaling Is Essential to Regulate Innate Immune Cells and Fight Bacterial Infection in Drosophila JC Regan, AS Brandão, AB Leitão, AR Mantas Dias, É Sucena, A Jacinto, ... PLoS pathogens 9 (10), e1003720, 2013 | 122 | 2013 |
An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry JC Regan, ML Concha, M Roussigne, C Russell, SW Wilson Neuron 61 (1), 27-34, 2009 | 107 | 2009 |
Hedgehog and Fgf signaling pathways regulate the development of tphR‐expressing serotonergic raphe neurons in zebrafish embryos H Teraoka, C Russell, J Regan, A Chandrasekhar, ML Concha, ... Journal of neurobiology 60 (3), 275-288, 2004 | 93 | 2004 |
Dietary restriction and insulin‐like signalling pathways as adaptive plasticity: A synthesis and re‐evaluation JC Regan, H Froy, CA Walling, JP Moatt, DH Nussey Functional Ecology 34 (1), 107-128, 2020 | 91 | 2020 |
Sexual Dimorphisms in Innate Immunity and Responses to Infection in Drosophila melanogaster RL Belmonte, MK Corbally, DF Duneau, JC Regan Frontiers in immunology 10, 3075, 2020 | 78 | 2020 |
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy P Juricic, YX Lu, T Leech, LF Drews, J Paulitz, J Lu, T Nespital, S Azami, ... Nature Aging 2 (9), 824-836, 2022 | 52 | 2022 |
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 52 | 2020 |
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing YX Lu, JC Regan, J Eßer, LF Drews, T Weinseis, J Stinn, O Hahn, ... Elife 10, e62233, 2021 | 50 | 2021 |
Intestinal fork head regulates nutrient absorption and promotes longevity E Bolukbasi, M Khericha, JC Regan, DK Ivanov, J Adcott, MC Dyson, ... Cell reports 21 (3), 641-653, 2017 | 42 | 2017 |
The Drosophila larva as a tool to study gut-associated macrophages: PI3K regulates a discrete hemocyte population at the proventriculus A Zaidman-Rémy, JC Regan, AS Brandão, A Jacinto Developmental & Comparative Immunology 36 (4), 638-647, 2012 | 37 | 2012 |
Lifespan extension via dietary restriction: time to reconsider the evolutionary mechanisms? JP Moatt, E Savola, JC Regan, DH Nussey, CA Walling BioEssays 42 (8), 1900241, 2020 | 31 | 2020 |
Drosophila Hemocyte Migration: An In Vivo Assay for Directional Cell Migration CGA Moreira, JC Regan, A Zaidman-Rémy, A Jacinto, S Prag Cell Migration: Developmental Methods and Protocols, 249-260, 2011 | 26 | 2011 |
Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin JC Regan, YX Lu, E Ureña, RL Meilenbrock, JH Catterson, D Kißler, ... Nature aging 2 (12), 1145-1158, 2022 | 14 | 2022 |
Analysis of gene transcription in cells lacking DNA-PK activity F Bryntesson, JC Regan, PA Jeggo, GE Taccioli, M Hubank Radiation research 156 (2), 167-176, 2001 | 13 | 2001 |
Cloning of apoptosis-related genes by representational difference analysis of cDNA M Hubank, F Bryntesson, J Regan, DG Schatz Apoptosis Methods and Protocols, 255-273, 2004 | 11 | 2004 |
Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes JC Regan, YX Lu, E Bolukbasi, M Khericha, L Partridge bioRxiv, 356295, 2018 | 5 | 2018 |
Profound geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy P Juricic, YX Lu, T Leech, LF Drews, J Paulitz, J Lu, T Nespital, S Azami, ... bioRxiv, 2022.04. 20.488884, 2022 | 4 | 2022 |