Phosphorylation of EZH2 by AMPK suppresses PRC2 methyltransferase activity and oncogenic function L Wan, K Xu, Y Wei, J Zhang, T Han, C Fry, Z Zhang, YV Wang, L Huang, ... Molecular cell 69 (2), 279-291. e5, 2018 | 170 | 2018 |
Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade X Dai, X Bu, Y Gao, J Guo, J Hu, C Jiang, Z Zhang, K Xu, J Duan, S He, ... Molecular cell 81 (11), 2317-2331. e6, 2021 | 117 | 2021 |
The differential transcription network between embryo and endosperm in the early developing maize seed X Lu, D Chen, D Shu, Z Zhang, W Wang, C Klukas, L Chen, Y Fan, ... Plant physiology 162 (1), 440-455, 2013 | 97 | 2013 |
Tamoxifen resistance in breast cancer is regulated by the EZH2–ERα–GREB1 transcriptional axis Y Wu, Z Zhang, ME Cenciarini, CJ Proietti, M Amasino, T Hong, M Yang, ... Cancer research 78 (3), 671-684, 2018 | 95 | 2018 |
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer C Zhu, L Li, Z Zhang, M Bi, H Wang, W Su, K Hernandez, P Liu, J Chen, ... Molecular cell 75 (4), 791-806. e8, 2019 | 94 | 2019 |
PlantNATsDB: a comprehensive database of plant natural antisense transcripts D Chen, C Yuan, J Zhang, Z Zhang, L Bai, Y Meng, LL Chen, M Chen Nucleic acids research 40 (D1), D1187-D1193, 2012 | 92 | 2012 |
Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance M Bi, Z Zhang, YZ Jiang, P Xue, H Wang, Z Lai, X Fu, C De Angelis, ... Nature cell biology 22 (6), 701-715, 2020 | 89 | 2020 |
MTide: an integrated tool for the identification of miRNA–target interaction in plants Z Zhang, L Jiang, J Wang, P Gu, M Chen Bioinformatics 31 (2), 290-291, 2015 | 77 | 2015 |
Genome-scale metabolic model in guiding metabolic engineering of microbial improvement C Xu, L Liu, Z Zhang, D Jin, J Qiu, M Chen Applied microbiology and biotechnology 97, 519-539, 2013 | 60 | 2013 |
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice K Qin, N Zhang, Z Zhang, M Nipper, Z Zhu, J Leighton, K Xu, N Musi, ... Diabetologia 61, 906-918, 2018 | 46 | 2018 |
Dissecting the chromatin interactome of microRNA genes D Chen, LY Fu, Z Zhang, G Li, H Zhang, L Jiang, AP Harrison, ... Nucleic acids research 42 (5), 3028-3043, 2014 | 35 | 2014 |
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic D Li, X Yu, J Kottur, W Gong, Z Zhang, AJ Storey, YH Tsai, H Uryu, Y Shen, ... Oncogene 41 (24), 3328-3340, 2022 | 30 | 2022 |
Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb JE Mayfield, S Irani, EE Escobar, Z Zhang, NT Burkholder, MR Robinson, ... eLife, 2019 | 30 | 2019 |
Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress Y Liao, CH Chen, T Xiao, B de la Peña Avalos, EV Dray, C Cai, S Gao, ... Proceedings of the National Academy of Sciences 119 (3), e2105898119, 2022 | 27 | 2022 |
Regulation of telomere homeostasis and genomic stability in cancer by N6-adenosine methylation (m6A) JH Lee, J Hong, Z Zhang, B de la Peña Avalos, CJ Proietti, AR Deamicis, ... Science Advances 7 (31), eabg7073, 2021 | 26 | 2021 |
Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer N Zhu, J Zhang, Y Du, X Qin, R Miao, J Nan, X Chen, J Sun, R Zhao, ... Proceedings of the National Academy of Sciences, 2020 | 23 | 2020 |
Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor M Yang, JH Lee, Z Zhang, R De La Rosa, M Bi, Y Tan, Y Liao, J Hong, ... Cell Reports, 2020 | 15 | 2020 |
Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF‐16 in C. elegans A Xu, Z Zhang, SH Ko, AL Fisher, Z Liu, L Chen Aging cell 18 (2), e12884, 2019 | 15 | 2019 |
Epigenomics-Based Identification of Estrogen-regulated Long Noncoding RNAs in ER+ Breast Cancer Z Zhang, W Yu, D Tang, Y Zhou, M Bi, H Wang, Y Zheng, M Chen, L Li, ... RNA Biology, 2020 | 11 | 2020 |
Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions L Chen, Z Zhang, Q Han, BK Maity, L Rodrigues, E Zboril, R Adhikari, ... Molecular Cell 83, 3438–3456, 2023 | 10 | 2023 |