Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development K Loh, JA Chia, S Greco, SJ Cozzi, RL Buttenshaw, CE Bond, LA Simms, ... Genes, Chromosomes and Cancer 47 (6), 449-460, 2008 | 106 | 2008 |
RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis CE Bond, DM McKeone, M Kalimutho, ML Bettington, SA Pearson, ... Oncotarget 7 (43), 70589, 2016 | 94 | 2016 |
Oncogenic PIK3CA mutations in colorectal cancers and polyps VLJ Whitehall, C Rickman, CE Bond, I Ramsnes, SA Greco, A Umapathy, ... International journal of cancer 131 (4), 813-820, 2012 | 94 | 2012 |
Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia CE Bond, C Liu, F Kawamata, DM McKeone, W Fernando, S Jamieson, ... Epigenetics 13 (1), 40-48, 2018 | 65 | 2018 |
The role of APC in WNT pathway activation in serrated neoplasia J Borowsky, T Dumenil, M Bettington, SA Pearson, C Bond, L Fennell, ... Modern Pathology 31 (3), 495-504, 2018 | 63 | 2018 |
How the BRAF V600E mutation defines a distinct subgroup of colorectal cancer: molecular and clinical implications CE Bond, VLJ Whitehall Gastroenterology research and practice 2018, 2018 | 59 | 2018 |
p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers CE Bond, A Umapathy, I Ramsnes, SA Greco, Z Zhen Zhao, KA Mallitt, ... International journal of cancer 130 (7), 1567-1576, 2012 | 52 | 2012 |
Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals 5 distinct subtypes of colorectal adenocarcinomas L Fennell, T Dumenil, L Wockner, G Hartel, K Nones, C Bond, J Borowsky, ... Cellular and molecular gastroenterology and hepatology 8 (2), 269-290, 2019 | 49 | 2019 |
APC Mutation marks an aggressive subtype of BRAF mutant colorectal cancers that are associated with early-onset and dismal prognosis L Fennell, A Kane, C Liu, D McKeone, W Fernando, C Bond, S Jamieson, ... bioRxiv, 2020 | 35* | 2020 |
Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability CE Bond, DJ Nancarrow, LF Wockner, L Wallace, GW Montgomery, ... PLoS One 9 (3), 2014 | 32 | 2014 |
Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers CE Bond, A Umapathy, RL Buttenshaw, L Wockner, BA Leggett, ... PloS one 7 (10), 2012 | 27 | 2012 |
Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype VLJ Whitehall, TD Dumenil, DM McKeone, CE Bond, ML Bettington, ... Epigenetics 9 (11), 1454-1460, 2014 | 25 | 2014 |
MLH1–93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation LJ Fennell, S Jamieson, D McKeone, T Corish, M Rohdmann, T Furner, ... BMC cancer 18 (1), 35, 2018 | 21 | 2018 |
Copy number profiles of paired primary and metastatic colorectal cancers F Kawamata, AM Patch, K Nones, C Bond, D McKeone, SA Pearson, ... Oncotarget 9 (3), 3394, 2018 | 18 | 2018 |
RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers LJ Fennell, M Clendenning, DM McKeone, SH Jamieson, S Balachandran, ... Familial cancer 17 (1), 63-69, 2018 | 18 | 2018 |
Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups CE Bond, ML Bettington, SA Pearson, DM McKeone, BA Leggett, ... BMC cancer 15 (1), 20, 2015 | 18 | 2015 |
Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer AM Kane, LJ Fennell, C Liu, J Borowsky, DM McKeone, CE Bond, ... Neoplasia 22 (2), 120-128, 2020 | 17 | 2020 |
Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium L Fennell, A Kane, C Liu, D McKeone, G Hartel, C Su, C Bond, ... Gut, 2021 | 13 | 2021 |
Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia AM Kane, C Liu, LJ Fennell, DM McKeone, CE Bond, PM Pollock, ... British Journal of Cancer 124 (11), 1820-1827, 2021 | 4 | 2021 |
Genome scale epigenetic profiling reveals five distinct subtypes of colorectal cancer L Fennell, T Dumenil, G Hartel, K Nones, C Bond, D Mckeone, L Bowdler, ... BioRxiv, 397620, 2018 | 2 | 2018 |