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Roch-Philippe Charles
Roch-Philippe Charles
University of Bern, Switzerland
在 ibmm.unibe.ch 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
A central role for RAF→ MEK→ ERK signaling in the genesis of pancreatic ductal adenocarcinoma
EA Collisson, CL Trejo, JM Silva, S Gu, JE Korkola, LM Heiser, ...
Cancer discovery 2 (8), 685-693, 2012
3402012
The epidermal barrier function is dependent on the serine protease CAP1/Prss8
C Leyvraz, RP Charles, I Rubera, M Guitard, S Rotman, B Breiden, ...
The Journal of cell biology 170 (3), 487-496, 2005
3132005
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import
I Mattioli, A Sebald, C Bucher, RP Charles, H Nakano, M Kracht, ...
The Journal of Immunology 172 (10), 6336-6344, 2004
2852004
The L-type amino acid transporter LAT1—An emerging target in cancer
P Häfliger, RP Charles
International journal of molecular sciences 20 (10), 2428, 2019
1802019
Mutationally activated BRAFV600E elicits papillary thyroid cancer in the adult mouse
RP Charles, G Iezza, E Amendola, D Dankort, M McMahon
Cancer research 71 (11), 3863-3871, 2011
1212011
Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis
RP Charles, J Silva, G Iezza, WA Phillips, M McMahon
Molecular Cancer Research 12 (7), 979-986, 2014
1202014
PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin
S Frateschi, E Camerer, G Crisante, S Rieser, M Membrez, RP Charles, ...
Nature communications 2 (1), 161, 2011
1122011
ENaC‐mediated alveolar fluid clearance and lung fluid balance depend on the channel‐activating protease 1
C Planès, NH Randrianarison, RP Charles, S Frateschi, F Cluzeaud, ...
EMBO molecular medicine 2 (1), 26-37, 2009
1022009
Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake
A Chicca, S Nicolussi, R Bartholomäus, M Blunder, A Aparisi Rey, ...
Proceedings of the National Academy of Sciences 114 (25), E5006-E5015, 2017
1002017
Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
S Boulkroun, D Ruffieux-Daidié, JJ Vitagliano, O Poirot, RP Charles, ...
American Journal of Physiology-Renal Physiology 295 (4), F889-F900, 2008
912008
The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model
P Häfliger, J Graff, M Rubin, A Stooss, MS Dettmer, KH Altmann, J Gertsch, ...
Journal of experimental & clinical cancer research 37, 1-15, 2018
842018
The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes
H Yang, RP Charles, E Hummler, DL Baines, RR Isseroff
Journal of cell science 126 (9), 1942-1951, 2013
802013
Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance
S Malsure, Q Wang, RP Charles, C Sergi, R Perrier, BM Christensen, ...
Journal of the American Society of Nephrology 25 (7), 1453-1464, 2014
782014
E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor
CY Li, W Cha, HU Luder, RP Charles, M McMahon, TA Mitsiadis, ...
Developmental biology 366 (2), 357-366, 2012
702012
Targeting CD47 in anaplastic thyroid carcinoma enhances tumor phagocytosis by macrophages and is a promising therapeutic strategy
CM Schürch, MA Roelli, S Forster, MH Wasmer, F Brühl, RS Maire, ...
Thyroid 29 (7), 979-992, 2019
672019
Optimization of TRPV6 calcium channel inhibitors using a 3D ligand‐based virtual screening method
C Simonin, M Awale, M Brand, R Van Deursen, J Schwartz, M Fine, ...
Angewandte Chemie International Edition 54 (49), 14748-14752, 2015
572015
Postnatal requirement of the epithelial sodium channel for maintenance of epidermal barrier function
RP Charles, M Guitard, C Leyvraz, B Breiden, M Haftek, Z Haftek-Terreau, ...
Journal of biological chemistry 283 (5), 2622-2630, 2008
502008
The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation
E Hummler, A Dousse, A Rieder, JC Stehle, I Rubera, MC Osterheld, ...
PloS one 8 (2), e55796, 2013
342013
Combined MEK and Pi3′-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo
O ElMokh, D Ruffieux-Daidié, MA Roelli, A Stooss, WA Phillips, J Gertsch, ...
Oncotarget 8 (15), 24604, 2017
282017
4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation
A Chicca, MS Gachet, V Petrucci, W Schuehly, RP Charles, J Gertsch
Journal of neuroinflammation 12, 1-16, 2015
282015
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