Evaluation of toxicity and degradation of a chlorophenol mixture by the laccase produced by Trametes pubescens IJ Gaitan, SC Medina, JC González, A Rodríguez, ÁJ Espejo, JF Osma, ... Bioresource Technology 102 (3), 3632-3635, 2011 | 109 | 2011 |
Therapeutic options for mucopolysaccharidoses: current and emerging treatments K Sawamoto, M Stapleton, CJ Alméciga-Díaz, AJ Espejo-Mojica, ... Drugs 79 (10), 1103-1134, 2019 | 86 | 2019 |
Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome STK Sawamoto, CJ Alméciga-Díaz, T Shimada, MB Bober, Y Chinen, ... Drug Design, Development and Therapy 9, 1937-1953, 2015 | 85 | 2015 |
GM2 gangliosidoses: clinical features, pathophysiological aspects, and current therapies AF Leal, E Benincore-Flórez, D Solano-Galarza, RG Garzón Jaramillo, ... International journal of molecular sciences 21 (17), 6213, 2020 | 83 | 2020 |
Lysosomal storage diseases: current therapies and future alternatives AF Leal, AJ Espejo-Mojica, OF Sánchez, CM Ramírez, LH Reyes, JC Cruz, ... Journal of Molecular Medicine 98 (7), 931-946, 2020 | 53 | 2020 |
Enzyme replacement therapy for Morquio A: an active recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in Escherichia coli BL21 A Rodríguez, ÁJ Espejo, A Hernández, OL Velásquez, LM Lizaraso, ... Journal of industrial microbiology and biotechnology 37 (11), 1193-1201, 2010 | 42 | 2010 |
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease M Vu, R Li, A Baskfield, B Lu, A Farkhondeh, K Gorshkov, O Motabar, ... Orphanet journal of rare diseases 13, 1-15, 2018 | 39 | 2018 |
Effect of elongation factor 1α promoter and SUMF1 over in vitro expression of N-acetylgalactosamine-6-sulfate sulfatase CJ Alméciga-Díaz, MA Rueda-Paramo, AJ Espejo, OY Echeverri, ... Molecular biology reports 36, 1863-1870, 2009 | 37 | 2009 |
Recombinant human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in the methylotrophic yeast Pichia pastoris A Rodríguez-López, CJ Alméciga-Díaz, J Sánchez, J Moreno, L Beltran, ... Scientific reports 6 (1), 29329, 2016 | 33 | 2016 |
Human recombinant lysosomal enzymes produced in microorganisms ÁJ Espejo-Mojica, CJ Alméciga-Díaz, A Rodríguez, Á Mosquera, D Díaz, ... Molecular genetics and metabolism 116 (1-2), 13-23, 2015 | 30 | 2015 |
Characterization of a recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in E. coli for enzyme replacement therapy of Morquio A disease A Mosquera, A Rodríguez, C Soto, F Leonardi, A Espejo, OF Sánchez, ... Process biochemistry 47 (12), 2097-2102, 2012 | 22 | 2012 |
Characterization of recombinant human lysosomal beta-hexosaminidases produced in the methylotrophic yeast Pichia pastoris AJ Espejo-Mojica, A Mosquera, A Rodrfguez-Lopez, D Diaz, L Beltran, ... Universitas Scientiarum 21 (3), 195-217, 2016 | 18 | 2016 |
Effect of culture conditions and signal peptide on production of human recombinant N-acetylgalactosamine-6-sulfate sulfatase in Escherichia coli BL21 A Hernández, O Velásquez, F Leonardi, C Soto, A Rodríguez, L Lizaraso, ... Journal of microbiology and biotechnology 23 (5), 689-698, 2013 | 18 | 2013 |
Production and characterization of a human lysosomal recombinant iduronate‐2‐sulfatase produced in Pichia pastoris N Pimentel, A Rodríguez‐Lopez, S Díaz, JC Losada, DJ Díaz‐Rincón, ... Biotechnology and applied biochemistry 65 (5), 655-664, 2018 | 17 | 2018 |
Research, diagnosis and education in inborn errors of metabolism in Colombia: 20 years’ experience from a reference center OY Echeverri, JM Guevara, ÁJ Espejo-Mojica, A Ardila, N Pulido, ... Orphanet journal of rare diseases 13, 1-12, 2018 | 15 | 2018 |
Development of a sandwich enzyme linked immunosorbent assay (ELISA) for the quantification of iduronate-2-sulfate sulfatase AC Sosa, AJ Espejo, EA Rodriguez, LM Lizaraso, A Rojas, J Guevara, ... Journal of immunological methods 368 (1-2), 64-70, 2011 | 15 | 2011 |
Characterization of human recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in Pichia pastoris as potential enzyme for mucopolysaccharidosis IVA treatment A Rodríguez-López, LN Pimentel-Vera, AJ Espejo-Mojica, A Van Hecke, ... Journal of Pharmaceutical Sciences 108 (8), 2534-2541, 2019 | 14 | 2019 |
Human recombinant lysosomal β‐Hexosaminidases produced in Pichia pastoris efficiently reduced lipid accumulation in Tay‐Sachs fibroblasts AJ Espejo‐Mojica, A Rodríguez‐López, R Li, W Zheng, CJ Alméciga‐Díaz, ... American Journal of Medical Genetics Part C: Seminars in Medical Genetics …, 2020 | 11 | 2020 |
A perspective on research, diagnosis, and management of lysosomal storage disorders in Colombia MA Puentes-Tellez, PA Lerma-Barbosa, RG Garzón-Jaramillo, DA Suarez, ... Heliyon 6 (3), 2020 | 9 | 2020 |
Delivery and assessment of a CRISPR/nCas9-based genome editing system on in vitro models of mucopolysaccharidoses IVA assisted by magnetite-based nanoparticles AF Leal, J Cifuentes, CE Torres, D Suárez, V Quezada, SC Gómez, ... Scientific Reports 12 (1), 15045, 2022 | 8 | 2022 |