Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation I Gerin, LA Clerbaux, O Haumont, N Lanthier, AK Das, CF Burant, ... Journal of biological chemistry 285 (44), 33652-33661, 2010 | 423 | 2010 |
Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways BD Pachikian, A Essaghir, JB Demoulin, E Catry, AM Neyrinck, ... Molecular nutrition & food research 57 (2), 347-359, 2013 | 123 | 2013 |
Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury R Manco, LA Clerbaux, S Verhulst, MB Nader, C Sempoux, J Ambroise, ... Journal of hepatology 70 (6), 1180-1191, 2019 | 69 | 2019 |
Bile acids contribute to the development of non-alcoholic steatohepatitis in mice J Gillard, LA Clerbaux, M Nachit, C Sempoux, B Staels, LB Bindels, ... JHEP reports 4 (1), 100387, 2022 | 49 | 2022 |
Liver regeneration: different sub-populations of parenchymal cells at play choreographed by an injury-specific microenvironment R Manco, IA Leclercq, LA Clerbaux International journal of molecular sciences 19 (12), 4115, 2018 | 35 | 2018 |
Invasive ductular reaction operates hepatobiliary junctions upon hepatocellular injury in rodents and humans LA Clerbaux, R Manco, N Van Hul, C Bouzin, A Sciarra, C Sempoux, ... The American journal of pathology 189 (8), 1569-1581, 2019 | 27 | 2019 |
Factors modulating COVID-19: A mechanistic understanding based on the adverse outcome pathway framework LA Clerbaux, MC Albertini, N Amigó, A Beronius, GFG Bezemer, ... Journal of Clinical Medicine 11 (15), 4464, 2022 | 26 | 2022 |
MCL1 is required for maintenance of intestinal homeostasis and prevention of carcinogenesis in mice ME Healy, Y Boege, MC Hodder, F Böhm, M Malehmir, AL Scherr, ... Gastroenterology 159 (1), 183-199, 2020 | 25 | 2020 |
Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives LA Clerbaux, A Paini, A Lumen, H Osman-Ponchet, AP Worth, O Fardel Environment international 126, 659-671, 2019 | 25 | 2019 |
Mechanisms leading to gut dysbiosis in COVID-19: current evidence and uncertainties based on adverse outcome pathways LA Clerbaux, J Filipovska, A Muñoz, M Petrillo, S Coecke, MJ Amorim, ... Journal of Clinical Medicine 11 (18), 5400, 2022 | 23 | 2022 |
Understanding COVID-19 through adverse outcome pathways–2nd CIAO AOP Design Workshop C Wittwehr, MJ Amorim, LA Clerbaux, C Krebs, B Landesmann, ... ALTEX-Alternatives to animal experimentation 38 (2), 351-357, 2021 | 19 | 2021 |
Capturing the applicability of in vitro-in silico membrane transporter data in chemical risk assessment and biomedical research LA Clerbaux, S Coecke, A Lumen, T Kliment, AP Worth, A Paini Science of the total environment 645, 97-108, 2018 | 18 | 2018 |
Effects of spike protein and toxin-like peptides found in COVID-19 patients on human 3D neuronal/glial model undergoing differentiation: Possible implications for SARS-CoV-2 … F Pistollato, M Petrillo, LA Clerbaux, G Leoni, J Ponti, A Bogni, C Brogna, ... Reproductive Toxicology 111, 34-48, 2022 | 17 | 2022 |
COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease–3rd CIAO AOP Design Workshop LA Clerbaux, N Amigó, MJ Amorim, A Bal-Price, SB Leite, A Beronius, ... Altex 39 (2), 322–335, 2022 | 16 | 2022 |
Mechanistic understanding of the olfactory neuroepithelium involvement leading to short-term anosmia in COVID-19 using the adverse outcome pathway framework MA Shahbaz, F De Bernardi, A Alatalo, M Sachana, LA Clerbaux, ... Cells 11 (19), 3027, 2022 | 15 | 2022 |
Gut as an alternative entry route for SARS-CoV-2: current evidence and uncertainties of productive enteric infection in COVID-19 LA Clerbaux, SA Mayasich, A Muñoz, H Soares, M Petrillo, MC Albertini, ... Journal of Clinical Medicine 11 (19), 5691, 2022 | 13 | 2022 |
The adverse outcome pathway framework applied to neurological symptoms of COVID-19 HT Hogberg, A Lam, E Ohayon, MA Shahbaz, LA Clerbaux, A Bal-Price, ... Cells 11 (21), 3411, 2022 | 10 | 2022 |
Relevance of the CDE and DDC mouse models to study ductular reaction in chronic human liver diseases LA Clerbaux, N Van Hul, ASH Gouw, R Manco, R Español-Suñer, ... Experimental Animal Models of Human Diseases-An Effective Therapeutic …, 2018 | 10 | 2018 |
The microRNA miR‐33 is a pleiotropic regulator of metabolic and developmental processes in Drosophila melanogaster LA Clerbaux, H Schultz, S Roman‐Holba, DF Ruan, R Yu, AM Lamb, ... Developmental dynamics 250 (11), 1634-1650, 2021 | 8 | 2021 |
Upstream regulators of hepatic Wnt/β‐catenin activity control liver metabolic zonation, development, and regeneration LA Clerbaux, R Manco, I Leclercq Hepatology 64 (4), 1361-1363, 2016 | 8 | 2016 |