Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3526 | 2010 |
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. RB Kim, MF Fromm, C Wandel, B Leake, AJ Wood, DM Roden, ... The Journal of clinical investigation 101 (2), 289-294, 1998 | 1322 | 1998 |
Identification of functionally variant MDR1 alleles among European Americans and African Americans RB Kim, BF Leake, EF Choo, GK Dresser, SV Kubba, UI Schwarz, ... Clinical Pharmacology & Therapeutics 70 (2), 189-199, 2001 | 1298 | 2001 |
Polymorphisms in Human MDR1 (P‐glycoprotein): Recent Advances and Clinical Relevance C Marzolini, E Paus, T Buclin, RB Kim Clinical Pharmacology & Therapeutics 75 (1), 13-33, 2004 | 1256 | 2004 |
SLC transporters as therapeutic targets: emerging opportunities L Lin, SW Yee, RB Kim, KM Giacomini Nature reviews Drug discovery 14 (8), 543-560, 2015 | 803 | 2015 |
Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study DW Haas, HJ Ribaudo, RB Kim, C Tierney, GR Wilkinson, RM Gulick, ... Aids 18 (18), 2391-2400, 2004 | 792 | 2004 |
Molecular basis of ethnic differences in drug disposition and response HG Xie, RB Kim, AJJ Wood, CM Stein Annual review of pharmacology and toxicology 41 (1), 815-850, 2001 | 763 | 2001 |
Genetic determinants of response to warfarin during initial anticoagulation UI Schwarz, MD Ritchie, Y Bradford, C Li, SM Dudek, A Frye-Anderson, ... New England Journal of Medicine 358 (10), 999-1008, 2008 | 762 | 2008 |
Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European-and African-Americans RG Tirona, BF Leake, G Merino, RB Kim Journal of Biological Chemistry 276 (38), 35669-35675, 2001 | 757 | 2001 |
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine M Cvetkovic, B Leake, MF Fromm, GR Wilkinson, RB Kim Drug metabolism and disposition 27 (8), 866-871, 1999 | 754 | 1999 |
Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine GK Dresser, DG Bailey, BF Leake, UI Schwarz, PA Dawson, DJ Freeman, ... Clinical pharmacology & therapeutics 71 (1), 11-20, 2002 | 741 | 2002 |
Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics RH Ho, RG Tirona, BF Leake, H Glaeser, W Lee, CJ Lemke, Y Wang, ... Gastroenterology 130 (6), 1793-1806, 2006 | 677 | 2006 |
Transporters and drug therapy: implications for drug disposition and disease RH Ho, RB Kim Clinical Pharmacology & Therapeutics 78 (3), 260-277, 2005 | 563 | 2005 |
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ... Nature medicine 9 (2), 220-224, 2003 | 552 | 2003 |
Drugs as P-glycoprotein substrates, inhibitors, and inducers RB Kim Drug metabolism reviews 34 (1-2), 47-54, 2002 | 528 | 2002 |
Inhibition of P-glycoprotein–mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine MF Fromm, RB Kim, CM Stein, GR Wilkinson, DM Roden Circulation 99 (4), 552-557, 1999 | 527 | 1999 |
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes EF Choo, B Leake, C Wandel, H Imamura, AJJ Wood, GR Wilkinson, ... Drug Metabolism and Disposition 28 (6), 655-660, 2000 | 499 | 2000 |
Intestinal drug transporter expression and the impact of grapefruit juice in humans H Glaeser, DG Bailey, GK Dresser, JC Gregor, UI Schwarz, JS McGrath, ... Clinical Pharmacology & Therapeutics 81 (3), 362-370, 2007 | 484 | 2007 |
The effect of common polymorphisms of the β2-adrenergic receptor on agonist-mediated vascular desensitization V Dishy, GG Sofowora, HG Xie, RB Kim, DW Byrne, CM Stein, AJJ Wood New England Journal of Medicine 345 (14), 1030-1035, 2001 | 470 | 2001 |
CYP2C9 allelic variants: ethnic distribution and functional significance HG Xie, HC Prasad, RB Kim, CM Stein Advanced drug delivery reviews 54 (10), 1257-1270, 2002 | 459 | 2002 |