Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118-1125, 2010 | 3150 | 2010 |
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease F Imhann, AV Vila, MJ Bonder, J Fu, D Gevers, MC Visschedijk, ... Gut 67 (1), 108-119, 2018 | 733 | 2018 |
Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome A Vich Vila, F Imhann, V Collij, SA Jankipersadsing, T Gurry, Z Mujagic, ... Science translational medicine 10 (472), eaap8914, 2018 | 479 | 2018 |
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA RSN Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, ... PLoS genetics 7 (8), e1002197, 2011 | 437 | 2011 |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, ... PLoS genetics 7 (2), e1002004, 2011 | 426 | 2011 |
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 338 | 2015 |
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP A Zhernakova, EM Festen, L Franke, G Trynka, CC van Diemen, ... The American Journal of Human Genetics 82 (5), 1202-1210, 2008 | 326 | 2008 |
Wnt signaling and Dupuytren's disease GH Dolmans, PM Werker, HC Hennies, D Furniss, EA Festen, L Franke, ... New England Journal of Medicine 365 (4), 307-317, 2011 | 319 | 2011 |
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease EAM Festen, P Goyette, T Green, G Boucher, C Beauchamp, G Trynka, ... PLoS genetics 7 (1), e1001283, 2011 | 276 | 2011 |
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes Y Momozawa, J Dmitrieva, E Théâtre, V Deffontaine, S Rahmouni, ... Nature communications 9 (1), 2427, 2018 | 221 | 2018 |
Molecular prediction of disease risk and severity in a large Dutch Crohn’s disease cohort RK Weersma, PCF Stokkers, AA van Bodegraven, RA van Hogezand, ... Gut 58 (3), 388-395, 2009 | 209 | 2009 |
Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis EAM Festen, P Goyette, R Scott, V Annese, A Zhernakova, J Lian, ... Gut 58 (6), 799-804, 2009 | 180 | 2009 |
The genetic background of inflammatory bowel disease: from correlation to causality WTC Uniken Venema, MD Voskuil, G Dijkstra, RK Weersma, EAM Festen The Journal of pathology 241 (2), 146-158, 2017 | 159 | 2017 |
Association of genetic variants in NUDT15 with thiopurine-induced myelosuppression in patients with inflammatory bowel disease GJ Walker, JW Harrison, GA Heap, MD Voskuil, V Andersen, ... Jama 321 (8), 773-785, 2019 | 141 | 2019 |
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease K Fransen, MC Visschedijk, S van Sommeren, JY Fu, L Franke, ... Human molecular genetics 19 (17), 3482-3488, 2010 | 126 | 2010 |
The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1 F Imhann, KJ Van der Velde, R Barbieri, R Alberts, MD Voskuil, ... BMC gastroenterology 19, 1-10, 2019 | 109 | 2019 |
Performance of the Montreal classification for inflammatory bowel diseases LM Spekhorst, MC Visschedijk, R Alberts, EA Festen, EJ van der Wouden, ... World Journal of Gastroenterology: WJG 20 (41), 15374, 2014 | 98 | 2014 |
Sex-related differences in patients with inflammatory bowel disease: results of 2 prospective cohort studies M Severs, LM Spekhorst, MJJ Mangen, G Dijkstra, M Löwenberg, ... Inflammatory bowel diseases 24 (6), 1298-1306, 2018 | 91 | 2018 |
Multi-ethnic studies in complex traits J Fu, EAM Festen, C Wijmenga Human molecular genetics 20 (R2), R206-R213, 2011 | 89 | 2011 |
Riboflavin Supplementation in Patients with Crohn’s Disease [the RISE-UP study] JZH von Martels, AR Bourgonje, MAY Klaassen, HAA Alkhalifah, ... Journal of Crohn's and Colitis 14 (5), 595-607, 2020 | 87 | 2020 |