Airway cytokine expression measured by means of protein array in exhaled breath condensate: correlation with physiologic properties in asthmatic patients K Matsunaga, S Yanagisawa, T Ichikawa, K Ueshima, K Akamatsu, ... Journal of Allergy and Clinical Immunology 118 (1), 84-90, 2006 | 164 | 2006 |
Activation of Toll-like receptor 3 augments myofibroblast differentiation H Sugiura, T Ichikawa, A Koarai, S Yanagisawa, Y Minakata, ... American journal of respiratory cell and molecular biology 40 (6), 654-662, 2009 | 80 | 2009 |
Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells A Koarai, H Sugiura, S Yanagisawa, T Ichikawa, Y Minakata, ... American journal of respiratory cell and molecular biology 42 (6), 651-660, 2010 | 71 | 2010 |
Inhibition of reactive nitrogen species production in COPD airways: comparison of inhaled corticosteroid and oral theophylline T Hirano, T Yamagata, M Gohda, Y Yamagata, T Ichikawa, S Yanagisawa, ... Thorax 61 (9), 761-766, 2006 | 71 | 2006 |
N-acetyl-l-cysteine inhibits TGF-β1-induced profibrotic responses in fibroblasts H Sugiura, T Ichikawa, X Liu, T Kobayashi, XQ Wang, S Kawasaki, S Togo, ... Pulmonary pharmacology & therapeutics 22 (6), 487-491, 2009 | 70 | 2009 |
25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells A Koarai, S Yanagisawa, H Sugiura, T Ichikawa, T Kikuchi, K Furukawa, ... Respiratory research 13, 1-11, 2012 | 69 | 2012 |
Overexpression of CD-11b and CXCR1 on circulating neutrophils: its possible role in COPD T Yamagata, H Sugiura, T Yokoyama, S Yanagisawa, T Ichikawa, ... Chest 132 (3), 890-899, 2007 | 67 | 2007 |
Ongoing allergic rhinitis impairs asthma control by enhancing the lower airway inflammation A Oka, K Matsunaga, T Kamei, Y Sakamoto, T Hirano, A Hayata, ... The Journal of Allergy and Clinical Immunology: In Practice 2 (2), 172-178. e1, 2014 | 64 | 2014 |
Oxidative stress enhances the expression of IL-33 in human airway epithelial cells H Aizawa, A Koarai, Y Shishikura, S Yanagisawa, M Yamaya, H Sugiura, ... Respiratory research 19, 1-12, 2018 | 55 | 2018 |
Reduced level of physical activity in Japanese patients with chronic obstructive pulmonary disease Y Minakata, A Sugino, M Kanda, T Ichikawa, K Akamatsu, A Koarai, ... Respiratory investigation 52 (1), 41-48, 2014 | 55 | 2014 |
Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation T Ichikawa, H Sugiura, A Koarai, S Yanagisawa, M Kanda, A Hayata, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (5 …, 2008 | 54 | 2008 |
Increased 25‐hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease H Sugiura, A Koarai, T Ichikawa, Y Minakata, K Matsunaga, T Hirano, ... Respirology 17 (3), 533-540, 2012 | 50 | 2012 |
Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects S Yanagisawa, A Koarai, H Sugiura, T Ichikawa, M Kanda, R Tanaka, ... Respiratory research 10, 1-13, 2009 | 45 | 2009 |
Effect of bronchial thermoplasty on structural changes and inflammatory mediators in the airways of subjects with severe asthma T Ichikawa, A Panariti, S Audusseau, AK Mogas, R Olivenstein, J Chakir, ... Respiratory medicine 150, 165-172, 2019 | 42 | 2019 |
Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells K Kanai, A Koarai, Y Shishikura, H Sugiura, T Ichikawa, T Kikuchi, ... Respiratory investigation 53 (4), 137-148, 2015 | 42 | 2015 |
25-hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway T Ichikawa, H Sugiura, A Koarai, T Kikuchi, M Hiramatsu, H Kawabata, ... Experimental cell research 319 (8), 1176-1186, 2013 | 41 | 2013 |
TLR3 activation augments matrix metalloproteinase production through reactive nitrogen species generation in human lung fibroblasts T Ichikawa, H Sugiura, A Koarai, Y Minakata, T Kikuchi, Y Morishita, ... The Journal of Immunology 192 (11), 4977-4988, 2014 | 37 | 2014 |
Cigarette smoke augments the expression and responses of toll‐like receptor 3 in human macrophages A Koarai, S Yanagisawa, H Sugiura, T Ichikawa, K Akamatsu, T Hirano, ... Respirology 17 (6), 1018-1025, 2012 | 37 | 2012 |
High COPD prevalence in patients with liver disease Y Minakata, H Ueda, K Akamatsu, M Kanda, S Yanagisawa, T Ichikawa, ... Internal Medicine 49 (24), 2687-2691, 2010 | 36 | 2010 |
Triple versus LAMA/LABA combination therapy for patients with COPD: a systematic review and meta-analysis A Koarai, M Yamada, T Ichikawa, N Fujino, T Kawayama, H Sugiura Respiratory research 22, 1-11, 2021 | 35 | 2021 |