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Ruben Cloete
Ruben Cloete
Dr of Structural Bioinformatics, University of the Western Cape
在 sanbi.ac.za 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints
CRE McEvoy, R Cloete, B Müller, AC Schürch, PD Van Helden, ...
PloS one 7 (4), e30593, 2012
1172012
Genetic variation in angiotensin-converting enzyme 2 gene is associated with extent of left ventricular hypertrophy in hypertrophic cardiomyopathy
L van der Merwe, R Cloete, M Revera, M Heradien, A Goosen, ...
Human genetics 124, 57-61, 2008
442008
Designing a course model for distance-based online bioinformatics training in Africa: the H3ABioNet experience
KT Gurwitz, S Aron, S Panji, S Maslamoney, PL Fernandes, DP Judge, ...
PLoS Computational Biology 13 (10), e1005715, 2017
382017
Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa
D Brado, AE Obasa, GM Ikomey, R Cloete, K Singh, S Engelbrecht, ...
Scientific reports 8 (1), 4709, 2018
362018
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders
K Cuttler, M Hassan, J Carr, R Cloete, S Bardien
Open biology 11 (10), 210091, 2021
342021
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis
R Cloete, E Oppon, E Murungi, WD Schubert, A Christoffels
Bmc Bioinformatics 17, 1-10, 2016
312016
Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c
R Cloete, E Kapp, J Joubert, A Christoffels, SF Malan
PLoS One 13 (11), e0207605, 2018
282018
Drug resistance mutations against protease, reverse transcriptase and integrase inhibitors in people living with HIV-1 receiving boosted protease inhibitors in South Africa
AE Obasa, SG Mikasi, D Brado, R Cloete, K Singh, U Neogi, GB Jacobs
Frontiers in microbiology 11, 438, 2020
252020
Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C Integrase-Dolutegravir binding
R Chitongo, AE Obasa, SG Mikasi, GB Jacobs, R Cloete
PLoS One 15 (5), e0223464, 2020
232020
HIV-1 integrase diversity and resistance-associated mutations and polymorphisms among integrase strand transfer inhibitor-naive HIV-1 patients from Cameroon
SG Mikasi, JO Gichana, C Van der Walt, D Brado, AE Obasa, D Njenda, ...
AIDS research and human retroviruses 36 (5), 450-455, 2020
172020
Structural and functional effects of nucleotide variation on the human TB drug metabolizing enzyme arylamine N-acetyltransferase 1
R Cloete, WA Akurugu, CJ Werely, PD van Helden, A Christoffels
Journal of Molecular Graphics and Modelling 75, 330-339, 2017
162017
Prioritization of candidate genes for a South African family with Parkinson’s disease using in-silico tools
B Sebate, K Cuttler, R Cloete, M Britz, A Christoffels, M Williams, J Carr, ...
PloS one 16 (3), e0249324, 2021
152021
Aptamer-based diagnostic systems for the rapid screening of TB at the point-of-care
DR Martin, NR Sibuyi, P Dube, AO Fadaka, R Cloete, M Onani, ...
Diagnostics 11 (8), 1352, 2021
132021
Molecular modeling of subtype-specific Tat protein signatures to predict Tat-TAR interactions that may be involved in HIV-associated neurocognitive disorders
ME Williams, R Cloete
Frontiers in Microbiology 13, 866611, 2022
112022
Structural comparison of diverse Hiv-1 subtypes using molecular modelling and docking analyses of integrase inhibitors
D Isaacs, SG Mikasi, AE Obasa, GM Ikomey, S Shityakov, R Cloete, ...
Viruses 12 (9), 936, 2020
92020
Genome sequencing of a severe acute respiratory syndrome coronavirus 2 isolate obtained from a South African Patient with coronavirus disease 2019
M Allam, A Ismail, ZTH Khumalo, S Kwenda, P van Heusden, R Cloete, ...
Microbiology Resource Announcements 9 (27), 10.1128/mra. 00572-20, 2020
92020
Interaction analysis of statistically enriched mutations identified in Cameroon recombinant subtype CRF02_AG that can influence the development of Dolutegravir drug resistance …
SG Mikasi, D Isaacs, R Chitongo, GM Ikomey, GB Jacobs, R Cloete
BMC infectious diseases 21 (1), 379, 2021
72021
HIV-1 drug resistance Mutation analyses of Cameroon-derived Integrase sequences
SG Mikasi, D Isaacs, GM Ikomey, H Shimba, R Cloete, GB Jacobs
AIDS Research and Human Retroviruses 37 (1), 54-56, 2021
62021
Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study
M Shahbaaz, R Cloete, M Grobbelaar, S Sampson, A Christoffels
International journal of biological macromolecules 135, 582-590, 2019
62019
The flexible, extended coil of the PDZ-Binding motif of the three deadly human coronavirus E proteins plays a role in pathogenicity
D Schoeman, R Cloete, BC Fielding
Viruses 14 (8), 1707, 2022
52022
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