Complement system part I–molecular mechanisms of activation and regulation NS Merle, SE Church, V Fremeaux-Bacchi, LT Roumenina Frontiers in immunology 6, 262, 2015 | 1679 | 2015 |
Complement system part II: role in immunity NS Merle, R Noe, L Halbwachs-Mecarelli, V Fremeaux-Bacchi, ... Frontiers in immunology 6, 257, 2015 | 1097 | 2015 |
Tumor cells hijack macrophage-produced complement C1q to promote tumor growth LT Roumenina, MV Daugan, R Noe, F Petitprez, YA Vano, ... Cancer immunology research 7 (7), 1091-1105, 2019 | 198 | 2019 |
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles NS Merle, A Grunenwald, H Rajaratnam, V Gnemmi, M Frimat, ... JCI insight 3 (12), 2018 | 162 | 2018 |
P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner NS Merle, R Paule, J Leon, M Daugan, T Robe-Rybkine, V Poillerat, ... Proceedings of the National Academy of Sciences 116 (13), 6280-6285, 2019 | 109 | 2019 |
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation N Niyonzima, J Rahman, N Kunz, EE West, T Freiwald, JV Desai, ... Science immunology 6 (66), eabf2489, 2021 | 67 | 2021 |
Characterization of renal injury and inflammation in an experimental model of intravascular hemolysis NS Merle, A Grunenwald, ML Figueres, S Chauvet, M Daugan, ... Frontiers in Immunology 9, 179, 2018 | 53 | 2018 |
Intracellular factor H drives tumor progression independently of the complement cascade MV Daugan, M Revel, R Thouenon, MA Dragon-Durey, T Robe-Rybkine, ... Cancer Immunology Research 9 (8), 909-925, 2021 | 47 | 2021 |
Heme drives susceptibility of glomerular endothelium to complement overactivation due to inefficient upregulation of heme oxygenase-1 O May, NS Merle, A Grunenwald, V Gnemmi, J Leon, C Payet, ... Frontiers in Immunology 9, 3008, 2018 | 43 | 2018 |
Complement activation during intravascular hemolysis: Implication for sickle cell disease and hemolytic transfusion reactions NS Merle, I Boudhabhay, J Leon, V Fremeaux-Bacchi, LT Roumenina Transfusion Clinique et Biologique 26 (2), 116-124, 2019 | 38 | 2019 |
Systematic single-cell pathway analysis to characterize early T cell activation JA Bibby, D Agarwal, T Freiwald, N Kunz, NS Merle, EE West, P Singh, ... Cell reports 41 (8), 2022 | 26 | 2022 |
Complement's favourite organelle—Mitochondria? J Rahman, P Singh, NS Merle, N Niyonzima, C Kemper British Journal of Pharmacology 178 (14), 2771-2785, 2021 | 25 | 2021 |
The receptor for advanced glycation end products is a sensor for cell‐free heme O May, L Yatime, NS Merle, F Delguste, M Howsam, MV Daugan, ... The FEBS Journal 288 (11), 3448-3464, 2021 | 23 | 2021 |
Integrins meet complement: The evolutionary tip of an iceberg orchestrating metabolism and immunity NS Merle, P Singh, J Rahman, C Kemper British Journal of Pharmacology 178 (14), 2754-2770, 2021 | 18 | 2021 |
Circulating FH protects kidneys from tubular injury during systemic hemolysis NS Merle, J Leon, V Poillerat, A Grunenwald, I Boudhabhay, S Knockaert, ... Frontiers in Immunology 11, 1772, 2020 | 11 | 2020 |
Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme M Wiatr, NS Merle, I Boudhabhay, V Poillerat, S Rossini, M Lecerf, ... Molecular immunology 111, 205-208, 2019 | 11 | 2019 |
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection EE West, NS Merle, MM Kamiński, G Palacios, D Kumar, L Wang, ... Immunity 56 (9), 2036-2053. e12, 2023 | 10 | 2023 |
A single-domain antibody targeting complement component C5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the C … L Yatime, NS Merle, AG Hansen, NA Friis, JA Østergaard, M Bjerre, ... Frontiers in Immunology 9, 2822, 2018 | 8 | 2018 |
Functional characterization of the disease-associated N-terminal complement factor H mutation W198R M Cserhalmi, B Uzonyi, NS Merle, D Csuka, E Meusburger, K Lhotta, ... Frontiers in Immunology 8, 1800, 2017 | 7 | 2017 |
Insights into the molecular basis and mechanism of heme‐triggered TLR4 signalling: The role of heme‐binding motifs in TLR4 and MD2 MT Hopp, J Holze, F Lauber, L Holtkamp, DC Rathod, MA Miteva, ... Immunology 171 (2), 181-197, 2024 | 3 | 2024 |