Intestinal mucosal barrier function in health and disease JR Turner Nature reviews immunology 9 (11), 799-809, 2009 | 3887 | 2009 |
The intestinal epithelial barrier: a therapeutic target? MA Odenwald, JR Turner Nature reviews Gastroenterology & hepatology 14 (1), 9-21, 2017 | 1016 | 2017 |
Tight junction pore and leak pathways: a dynamic duo L Shen, CR Weber, DR Raleigh, D Yu, JR Turner Annual review of physiology 73 (1), 283-309, 2011 | 930 | 2011 |
Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression F Wang, WV Graham, Y Wang, ED Witkowski, BT Schwarz, JR Turner The American journal of pathology 166 (2), 409-419, 2005 | 805 | 2005 |
Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application JR Turner The American journal of pathology 169 (6), 1901-1909, 2006 | 721 | 2006 |
Epithelial barriers in homeostasis and disease AM Marchiando, WV Graham, JR Turner Annual Review of Pathology: Mechanisms of Disease 5 (1), 119-144, 2010 | 709 | 2010 |
Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells A Nusrat, JR Turner, JL Madara American Journal of Physiology 279 (1), G851-G857, 2000 | 668 | 2000 |
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation JR Turner, BK Rill, SL Carlson, D Carnes, R Kerner, RJ Mrsny, JL Madara American Journal of Physiology-Cell Physiology 273 (4), C1378-C1385, 1997 | 641 | 1997 |
A porous defense: the leaky epithelial barrier in intestinal disease DR Clayburgh, L Shen, JR Turner Laboratory investigation 84 (3), 282-291, 2004 | 616 | 2004 |
Cell biology of tight junction barrier regulation and mucosal disease A Buckley, JR Turner Cold Spring Harbor perspectives in biology 10 (1), a029314, 2018 | 587 | 2018 |
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure L Shen, ED Black, ED Witkowski, WI Lencer, V Guerriero, ... Journal of cell science 119 (10), 2095-2106, 2006 | 529 | 2006 |
Hypoxia-inducible factor 1–dependent induction of intestinal trefoil factor protects barrier function during hypoxia GT Furuta, JR Turner, CT Taylor, RM Hershberg, K Comerford, ... The Journal of experimental medicine 193 (9), 1027-1034, 2001 | 527 | 2001 |
Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. A Nusrat, M Giry, JR Turner, SP Colgan, CA Parkos, D Carnes, ... Proceedings of the National Academy of Sciences 92 (23), 10629-10633, 1995 | 506 | 1995 |
Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b. T Seya, JR Turner, JP Atkinson The Journal of experimental medicine 163 (4), 837-855, 1986 | 495 | 1986 |
Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection S Liu, W Yang, L Shen, JR Turner, CB Coyne, T Wang Journal of virology 83 (4), 2011-2014, 2009 | 493 | 2009 |
Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis L Su, L Shen, DR Clayburgh, SC Nalle, EA Sullivan, JB Meddings, ... Gastroenterology 136 (2), 551-563, 2009 | 478 | 2009 |
Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo AM Marchiando, L Shen, WV Graham, CR Weber, BT Schwarz, JR Austin, ... Journal of Cell Biology 189 (1), 111-126, 2010 | 477 | 2010 |
Epithelial myosin light chain kinase–dependent barrier dysfunction mediates T cell activation–induced diarrhea in vivo DR Clayburgh, TA Barrett, Y Tang, JB Meddings, LJ Van Eldik, ... The Journal of clinical investigation 115 (10), 2702-2715, 2005 | 467 | 2005 |
CD95 promotes tumour growth L Chen, SM Park, AV Tumanov, A Hau, K Sawada, C Feig, JR Turner, ... Nature 465 (7297), 492-496, 2010 | 456 | 2010 |
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease Y Zolotarevsky, G Hecht, A Koutsouris, DE Gonzalez, C Quan, J Tom, ... Gastroenterology 123 (1), 163-172, 2002 | 451 | 2002 |