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Hong-Ru Chen
Hong-Ru Chen
Assistant Professor, Department of Neuroscience, Center for Brain Immunology and Glia
在 virginia.edu 的电子邮件经过验证
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Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice
K Bisht, KA Okojie, K Sharma, DH Lentferink, YY Sun, HR Chen, ...
Nature communications 12 (1), 5289, 2021
1642021
Cdk12 is essential for embryonic development and the maintenance of genomic stability
HC Juan, Y Lin, HR Chen, MJ Fann
Cell Death & Differentiation 23 (6), 1038-1048, 2016
942016
Fate mapping via CCR2-CreER mice reveals monocyte-to-microglia transition in development and neonatal stroke
HR Chen, YY Sun, CW Chen, YM Kuo, IS Kuan, ZR Tiger Li, ...
Science advances 6 (35), eabb2119, 2020
742020
Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression
HR Chen, GT Lin, CK Huang, MJ Fann
Experimental Neurology 261, 10-21, 2014
482014
Monocytes promote acute neuroinflammation and become pathological microglia in neonatal hypoxic-ischemic brain injury
HR Chen, CW Chen, YM Kuo, B Chen, IS Kuan, H Huang, J Lee, ...
Theranostics 12 (2), 512, 2022
302022
Monocytic infiltrates contribute to autistic-like behaviors in a two-hit model of neurodevelopmental defects
HR Chen, CW Chen, N Mandhani, JC Short-Miller, MR Smucker, YY Sun, ...
Journal of Neuroscience 40 (49), 9386-9400, 2020
282020
Cdk12 regulates neurogenesis and late-arising neuronal migration in the developing cerebral cortex
HR Chen, HC Juan, YH Wong, JW Tsai, MJ Fann
Cerebral cortex 27 (3), 2289-2302, 2017
272017
A murine photothrombotic stroke model with an increased fibrin content and improved responses to tPA-lytic treatment
YY Sun, YM Kuo, HR Chen, JC Short-Miller, MR Smucker, CY Kuan
Blood advances 4 (7), 1222-1231, 2020
262020
Creatine transporter deficiency impairs stress adaptation and brain energetics homeostasis
HR Chen, X Zhang-Brotzge, YM Morozov, Y Li, S Wang, HH Zhang, ...
JCI insight 6 (17), 2021
142021
Brain-targeted hypoxia-inducible factor stabilization reduces neonatal hypoxic-ischemic brain injury
CY Kuan, HR Chen, N Gao, YM Kuo, CW Chen, D Yang, MM Kinkaid, ...
Neurobiology of disease 148, 105200, 2021
132021
Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status
HR Chen, HC Yang, DJY Hsieh, Z Liu, KJ Tsai
Chemico-biological interactions 189 (3), 192-197, 2011
122011
(Phospho) creatine: the reserve and merry-go-round of brain energetics
HR Chen, T DeGrauw, CY Kuan
Neural Regeneration Research 18 (2), 327-328, 2023
22023
Stroke propensity in the Th3+/mouse model of β-thalassemia intermedia
YY Sun, HW Yao, HR Chen, CW Chen, MM Kinkaid, CY Kuan
Neurobiology of disease 171, 105802, 2022
22022
Hyperphosphorylated tau inflicts intracellular stress responses that are mitigated by apomorphine
Z Song, KW Wang, HTC Hagar, HR Chen, CY Kuan, K Zhang, MH Kuo
Molecular Neurobiology, 1-19, 2023
12023
P-tau Inflicts Intracellular Stress Responses That Are Mitigated by Apomorphine
Z Song, K Wang, HC Hagar, H Chen, C Kuan, K Zhang, M Kuo
2023
(磷酸) 肌酸: 大脑能量的储备和旋转木马
HR Chen, T DeGrauw, CY Kuan
中国神经再生研究 (英文版) 18 (2), 327, 2023
2023
Hypothermia Suppresses Uncoupling of Oxidative-Phosphorylation after Neonatal Cerebral Hypoxia-Ischemia
N Sun, YY Sun, R Cao, HR Chen, Y Wang, E Fugate, MR Smucker, ...
bioRxiv, 2021.11. 29.470404, 2021
2021
Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling
K Bisht, KA Okojie, K Sharma, DH Lentferink, YY Sun, HR Chen, ...
bioRxiv, 2021.08. 02.454769, 2021
2021
Creatine Transporter (CrT) Deficiency Impairs Brain Energetics Under Stress
HR Chen, X Zhang-Brotzge, TJ DeGrauw, DM Lindquist, S Wang, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859, e74, 2018
2018
Prenatal Maternal Immune Activation Sensitizes the Neuroinflammatory Responses to Neonatal Hypoxic-Ischemic Brain Injury
CY Kuan, HR Chen
The Journal of Immunology 200 (1_Supplement), 166.58-166.58, 2018
2018
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