Confinement of therapeutic enzymes in selectively permeable polymer vesicles by polymerization-induced self-assembly (PISA) reduces antibody binding and proteolytic susceptibility LD Blackman, S Varlas, MC Arno, ZH Houston, NL Fletcher, KJ Thurecht, ... ACS central science 4 (6), 718-723, 2018 | 193 | 2018 |
Efficient synthesis of diverse heterobifunctionalized clickable oligo (ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery LN Goswami, ZH Houston, SJ Sarma, SS Jalisatgi, MF Hawthorne Organic & biomolecular chemistry 11 (7), 1116-1126, 2013 | 94 | 2013 |
Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic AK Pearce, JD Simpson, NL Fletcher, ZH Houston, AV Fuchs, PJ Russell, ... Biomaterials 141, 330-339, 2017 | 78 | 2017 |
Overcoming instability of antibody‐nanomaterial conjugates: next generation targeted nanomedicines using bispecific antibodies CB Howard, N Fletcher, ZH Houston, AV Fuchs, NRB Boase, JD Simpson, ... Advanced healthcare materials 5 (16), 2055-2068, 2016 | 63 | 2016 |
Using peptide aptamer targeted polymers as a model nanomedicine for investigating drug distribution in cancer nanotheranostics Y Zhao, ZH Houston, JD Simpson, L Chen, NL Fletcher, AV Fuchs, ... Molecular Pharmaceutics 14 (10), 3539-3549, 2017 | 51 | 2017 |
Modulating targeting of poly (ethylene glycol) particles to tumor cells using bispecific antibodies J Cui, Y Ju, ZH Houston, JJ Glass, NL Fletcher, S Alcantara, Q Dai, ... Advanced healthcare materials 8 (9), 1801607, 2019 | 44 | 2019 |
Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies ZH Houston, J Bunt, KS Chen, S Puttick, CB Howard, NL Fletcher, ... ACS central science 6 (5), 727-738, 2020 | 43 | 2020 |
Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation SS Thakur, YS Chen, ZH Houston, N Fletcher, NL Barnett, KJ Thurecht, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 102-107, 2019 | 41 | 2019 |
Designed multifunctional polymeric nanomedicines: Long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials NL Fletcher, ZH Houston, JD Simpson, RN Veedu, KJ Thurecht Chemical communications 54 (82), 11538-11541, 2018 | 38 | 2018 |
Gold nanocluster-mediated cellular death under electromagnetic radiation A Cifuentes-Rius, A Ivask, S Das, N Penya-Auladell, L Fabregas, ... ACS applied materials & interfaces 9 (47), 41159-41167, 2017 | 38 | 2017 |
Controlling the biological fate of micellar nanoparticles: Balancing stealth and targeting AJ Sivaram, A Wardiana, S Alcantara, SE Sonderegger, NL Fletcher, ... ACS nano 14 (10), 13739-13753, 2020 | 37 | 2020 |
A convenient route to diversely substituted icosahedral closomer nanoscaffolds SS Jalisatgi, VS Kulkarni, B Tang, ZH Houston, MW Lee Jr, MF Hawthorne Journal of the American Chemical Society 133 (32), 12382-12385, 2011 | 35 | 2011 |
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract AM Dos Santos, AB Meneguin, DT Akhter, N Fletcher, ZH Houston, C Bell, ... European Journal of Pharmaceutics and Biopharmaceutics 158, 371-378, 2021 | 31 | 2021 |
Innovative therapeutic strategies for effective treatment of brain metastases M Lim, S Puttick, ZH Houston, KJ Thurecht, P Kalita-de Croft, S Mahler, ... International journal of molecular sciences 20 (6), 1280, 2019 | 26 | 2019 |
In vivo therapeutic evaluation of polymeric nanomedicines: effect of different targeting peptides on therapeutic efficacy against breast cancer Y Zhao, NL Fletcher, T Liu, AC Gemmell, ZH Houston, I Blakey, ... Nanotheranostics 2 (4), 360, 2018 | 26 | 2018 |
Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery GR Ediriweera, JD Simpson, AV Fuchs, TK Venkatachalam, ... Chemical Science 11 (12), 3268-3280, 2020 | 25 | 2020 |
Influence of charge on hemocompatibility and immunoreactivity of polymeric nanoparticles L Chen, JJ Glass, R De Rose, C Sperling, SJ Kent, ZH Houston, ... ACS Applied Bio Materials 1 (3), 756-767, 2018 | 25 | 2018 |
Importance of polymer length in fructose-based polymeric micelles for an enhanced biological activity M Lu, F Chen, C Cao, CJ Garvey, NL Fletcher, ZH Houston, H Lu, ... Macromolecules 52 (2), 477-486, 2019 | 23 | 2019 |
Hyperbranched poly (2-oxazoline) s and poly (ethylene glycol): a structure–activity comparison of biodistribution J Humphries, D Pizzi, SE Sonderegger, NL Fletcher, ZH Houston, CA Bell, ... Biomacromolecules 21 (8), 3318-3331, 2020 | 22 | 2020 |
Modified organosilica core–shell nanoparticles for stable pH sensing in biological solutions KJ Robinson, GT Huynh, BP Kouskousis, NL Fletcher, ZH Houston, ... ACS sensors 3 (5), 967-975, 2018 | 22 | 2018 |