Advances in the chemical biology of desferrioxamine B R Codd, T Richardson-Sanchez, TJ Telfer, MP Gotsbacher ACS Chemical Biology 13 (1), 11-25, 2018 | 81 | 2018 |
Exploiting the biosynthetic machinery of Streptomyces pilosus to engineer a water-soluble zirconium (iv) chelator T Richardson-Sanchez, W Tieu, MP Gotsbacher, TJ Telfer, R Codd Organic & Biomolecular Chemistry 15 (27), 5719-5730, 2017 | 47 | 2017 |
New Antimicrobial Bromotyrosine Analogues from the Sponge Pseudoceratina purpurea and Its Predator Tylodina corticalis MP Gotsbacher, P Karuso Marine Drugs 13 (3), 1389-1409, 2015 | 43 | 2015 |
Mixing up the pieces of the desferrioxamine B jigsaw defines the biosynthetic sequence catalyzed by DesD TJ Telfer, MP Gotsbacher, CZ Soe, R Codd ACS chemical biology 11 (5), 1452-1462, 2016 | 32 | 2016 |
Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate MP Gotsbacher, SM Cho, NH Kim, F Liu, HJ Kwon, P Karuso ACS chemical biology 14 (4), 636-643, 2019 | 26 | 2019 |
Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson’s disease MP Gotsbacher, TJ Telfer, PK Witting, KL Double, DI Finkelstein, R Codd Metallomics 9 (7), 852-864, 2017 | 25 | 2017 |
Improved access to linear tetrameric hydroxamic acids with potential as radiochemical ligands for zirconium (IV)-89 PET imaging CJM Brown, MP Gotsbacher, R Codd Australian Journal of Chemistry 73 (10), 969-978, 2020 | 17 | 2020 |
Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans MP Gotsbacher, S Cho, HJ Kwon, P Karuso Proteome Science 15, 1-15, 2016 | 16 | 2016 |
Analogues of desferrioxamine B (DFOB) with new properties and new functions generated using precursor-directed biosynthesis TJ Telfer, T Richardson-Sanchez, MP Gotsbacher, KP Nolan, W Tieu, ... Biometals 32, 395-408, 2019 | 13 | 2019 |
endo-Hydroxamic Acid Monomers for the Assembly of a Suite of Non-native Dimeric Macrocyclic Siderophores Using Metal-Templated Synthesis CJM Brown, MP Gotsbacher, JP Holland, R Codd Inorganic chemistry 58 (20), 13591-13603, 2019 | 11 | 2019 |
Azido‐Desferrioxamine Siderophores as Functional Click‐Chemistry Probes Generated in Culture upon Adding a Diazo‐Transfer Reagent MP Gotsbacher, R Codd ChemBioChem 21 (10), 1433-1445, 2020 | 7 | 2020 |
Immobilized metal affinity chromatography as a drug discovery platform for metalloenzyme inhibitors L Roth, MP Gotsbacher, R Codd Journal of medicinal chemistry 63 (20), 12116-12127, 2020 | 6 | 2020 |
Preparation of a dithiol-reactive probe for PET imaging of cell death I Ho Shon, MP Gotsbacher, J Guille, D Kumar, R Codd, P Hogg Functional Disulphide Bonds: Methods and Protocols, 295-304, 2019 | 6 | 2019 |
Acetyl-CoA-Mediated Post-Biosynthetic Modification of Desferrioxamine B Generates N- and N-O-Acetylated Isomers Controlled by a pH Switch KP Nolan, J Font, A Sresutharsan, MP Gotsbacher, CJM Brown, RM Ryan, ... ACS Chemical Biology 17 (2), 426-437, 2022 | 4 | 2022 |
A first-in-human study of [68Ga] Ga-CDI: a positron emitting radiopharmaceutical for imaging tumour cell death I Ho Shon, T Hennessy, J Guille, MP Gotsbacher, AJ Lay, B McBride, ... European Journal of Nuclear Medicine and Molecular Imaging 49 (12), 4037-4047, 2022 | 2 | 2022 |
Exploring hydroxamic acid inhibitors of HDAC1 and HDAC2 using small molecule tools and molecular or homology modelling L Daniel, MP Gotsbacher, T Richardson-Sanchez, W Tieu, R Codd Bioorganic & Medicinal Chemistry Letters 29 (18), 2581-2586, 2019 | 1 | 2019 |
Adding a diazo-transfer reagent to culture to generate secondary metabolite probes for click chemistry MP Gotsbacher, R Codd Methods in Enzymology 665, 49-71, 2022 | | 2022 |
Cover Feature: Azido‐Desferrioxamine Siderophores as Functional Click‐Chemistry Probes Generated in Culture upon Adding a Diazo‐Transfer Reagent (ChemBioChem 10/2020) MP Gotsbacher, R Codd ChemBioChem 21 (10), 1384-1384, 2020 | | 2020 |
A first in human study of Cell Death Indicator positron emission tomography (CDI-PET)-interim analysis. IH Shon, T Hennessy, J Guille, M Gotsbacher, M Horsfield, B McBride, ... Journal of Nuclear Medicine 61 (supplement 1), 344-344, 2020 | | 2020 |
Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease R Codd, K Double, M Gotsbacher, T Telfer, P Witting, D Finkelstein RSC Publications, 2017 | | 2017 |