| Animal models reflecting chronic obstructive pulmonary disease and related respiratory disorders: translating pre-clinical data into clinical relevance L Tanner, AB Single Journal of innate immunity 12 (3), 203-225, 2020 | 86 | 2020 |
| Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model L Tanner, AB Single, RKV Bhongir, M Heusel, T Mohanty, CAQ Karlsson, ... Nature communications 14 (1), 643, 2023 | 28 | 2023 |
| Drug permeation and metabolism in Mycobacterium tuberculosis: Prioritising local exposure as essential criterion in new TB drug development L Tanner, P Denti, L Wiesner, DF Warner IUBMB life 70 (9), 926-937, 2018 | 27 | 2018 |
| An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives L Tanner, RK Haynes, L Wiesner Frontiers in Pharmacology 10, 120, 2019 | 21 | 2019 |
| Lerisetron analogues with antimalarial properties: Synthesis, structure–activity relationship studies, and biological assessment R Mueller, V Reddy, AT Nchinda, F Mebrahtu, D Taylor, N Lawrence, ... ACS omega 5 (12), 6967-6982, 2020 | 17 | 2020 |
| Experimental model of pulmonary inflammation induced by SARS-CoV-2 spike protein and endotoxin M Puthia, L Tanner, G Petruk, A Schmidtchen ACS Pharmacology & Translational Science 5 (3), 141-148, 2022 | 16 | 2022 |
| Citrullination of extracellular histone H3. 1 reduces antibacterial activity and exacerbates its proteolytic degradation L Tanner, RKV Bhongir, CAQ Karlsson, S Le, JK Ljungberg, P Andersson, ... Journal of Cystic Fibrosis 20 (2), 346-355, 2021 | 14 | 2021 |
| Innate immune responses to RSV infection facilitated by OGG1, an enzyme repairing oxidatively modified DNA base lesions X Zheng, K Wang, L Pan, W Hao, Y Xue, A Bacsi, SA Vlahopoulos, ... Journal of innate immunity 14 (6), 593-614, 2022 | 12 | 2022 |
| Intracellular accumulation of novel and clinically used tb drugs potentiates intracellular synergy L Tanner, GT Mashabela, CC Omollo, TJ de Wet, CJ Parkinson, ... Microbiology spectrum 9 (2), e00434-21, 2021 | 11 | 2021 |
| Pharmacological OGG1 inhibition decreases murine allergic airway inflammation L Tanner, J Bergwik, RKV Bhongir, L Pan, C Dong, O Wallner, C Kalderén, ... Frontiers in Pharmacology 13, 4441, 2022 | 10 | 2022 |
| 8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury L Pan, W Hao, Y Xue, K Wang, X Zheng, J Luo, X Ba, Y Xiang, X Qin, ... Nucleic acids research 51 (3), 1087-1102, 2023 | 8 | 2023 |
| Accumulation of TB-Active Compounds in Murine Organs Relevant to Infection by Mycobacterium tuberculosis L Tanner, RK Haynes, L Wiesner Frontiers in Pharmacology 11, 724, 2020 | 6 | 2020 |
| In Vitro Efficacies, ADME, and Pharmacokinetic Properties of Phenoxazine Derivatives Active against Mycobacterium tuberculosis L Tanner, JC Evans, R Seldon, A Jordaan, DF Warner, RK Haynes, ... Antimicrobial Agents and Chemotherapy 63 (11), 10.1128/aac. 01010-19, 2019 | 4 | 2019 |
| Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury L Pan, S Vlahopoulos, L Tanner, J Bergwik, A Bacsi, Z Radak, A Egesten, ... Frontiers in immunology 14, 1186369, 2023 | 3 | 2023 |
| Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis L Tanner, J Bergwik, AB Single, RKV Bhongir, JS Erjefält, A Egesten Frontiers in Pharmacology 13, 899469, 2022 | 3 | 2022 |
| Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis L Tanner, AB Single, RKV Bonghir, R Oomen, O Wallner, T Helleday, ... bioRxiv, 2021.02. 27.433075, 2021 | 3 | 2021 |
| Macrophage expressed tartrate‐resistant acid phosphatase 5 promotes pulmonary fibrosis progression J Bergwik, RKV Bhongir, M Padra, A Adler, F Olm, P Lång, S Lindstedt, ... Immunology 171 (4), 583-594, 2024 | 2 | 2024 |
| Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1 Y Xue, L Pan, S Vlahopoulos, K Wang, X Zheng, Z Radak, A Bacsi, ... Frontiers in immunology 14, 1161160, 2023 | 2 | 2023 |
| Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection L Tanner, J Bergwik, RKV Bhongir, M Puthia, P Lång, M Ali, C Welinder, ... Frontiers in Immunology, 7357, 2022 | 1 | 2022 |
| Zoledronic acid targets the mevalonate pathway causing reduced cell recruitment and attenuation of pulmonary fibrosis L Tanner, J Bergwik, RKV Bhongir, A Egesten bioRxiv, 2021.12. 01.470755, 2021 | 1 | 2021 |
Digby WarnerProfessor, University of Cape Town在 uct.ac.za 的电子邮件经过验证
