[19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors JA Ballesteros, H Weinstein Methods in neurosciences 25, 366-428, 1995 | 3156 | 1995 |
Functional selectivity and classical concepts of quantitative pharmacology JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007 | 1312 | 2007 |
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac M Max, YG Shanker, L Huang, M Rong, Z Liu, F Campagne, H Weinstein, ... Nature genetics 28 (1), 58-63, 2001 | 684 | 2001 |
Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor SC Sealfon, H Weinstein, RP Millar Endocrine reviews 18 (2), 180-205, 1997 | 604 | 1997 |
Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor U Gether, S Lin, P Ghanouni, JA Ballesteros, H Weinstein, BK Kobilka The EMBO journal, 1997 | 505 | 1997 |
The mechanism of a neurotransmitter: sodium symporter—inward release of Na+ and substrate is triggered by substrate in a second binding site L Shi, M Quick, Y Zhao, H Weinstein, JA Javitch Molecular cell 30 (6), 667-677, 2008 | 428 | 2008 |
The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 413 | 2008 |
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation Y Han, IS Moreira, E Urizar, H Weinstein, JA Javitch Nature chemical biology 5 (9), 688-695, 2009 | 400 | 2009 |
Structural instability of a constitutively active G protein-coupled receptor: agonist-independent activation due to conformational flexibility U Gether, R Seifert, JA Ballesteros, E Sanders-Bush, H Weinstein, ... Journal of Biological Chemistry 272 (5), 2587-2590, 1997 | 353 | 1997 |
Hinges, swivels and switches: the role of prolines in signalling via transmembrane α-helices MSP Sansom, H Weinstein Trends in pharmacological sciences 21 (11), 445-451, 2000 | 351 | 2000 |
Functional microdomains in G-protein-coupled receptors: the conserved arginine-cage motif in the gonadotropin-releasing hormone receptor J Ballesteros, S Kitanovic, F Guarnieri, P Davies, BJ Fromme, K Konvicka, ... Journal of Biological Chemistry 273 (17), 10445-10453, 1998 | 330 | 1998 |
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor. W Zhou, C Flanagan, JA Ballesteros, K Konvicka, JS Davidson, ... Molecular pharmacology 45 (2), 165-170, 1994 | 325 | 1994 |
A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and … T Beuming, L Shi, JA Javitch, H Weinstein Molecular pharmacology 70 (5), 1630-1642, 2006 | 323 | 2006 |
Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation W Guo, L Shi, M Filizola, H Weinstein, JA Javitch Proceedings of the National Academy of Sciences 102 (48), 17495-17500, 2005 | 319 | 2005 |
Single-molecule analysis of ligand efficacy in β2AR–G-protein activation GG Gregorio, M Masureel, D Hilger, DS Terry, M Juette, H Zhao, Z Zhou, ... Nature 547 (7661), 68-73, 2017 | 315 | 2017 |
A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding N Pastor, H Weinstein, E Jamison, M Brenowitz Journal of molecular biology 304 (1), 55-68, 2000 | 312 | 2000 |
Single-molecule dynamics of gating in a neurotransmitter transporter homologue Y Zhao, D Terry, L Shi, H Weinstein, SC Blanchard, JA Javitch Nature 465 (7295), 188-193, 2010 | 278 | 2010 |
Related Contribution of Specific Helix 2 and 7 Residues to Conformational Activation of the Serotonin 5-HT2A Receptor (∗) SC Sealfon, L Chi, BJ Ebersole, V Rodic, D Zhang, JA Ballesteros, ... Journal of Biological Chemistry 270 (28), 16683-16688, 1995 | 258 | 1995 |
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue Y Zhao, DS Terry, L Shi, M Quick, H Weinstein, SC Blanchard, JA Javitch Nature 474 (7349), 109-113, 2011 | 255 | 2011 |
PDZBase: a protein–protein interaction database for PDZ-domains T Beuming, L Skrabanek, MY Niv, P Mukherjee, H Weinstein Bioinformatics 21 (6), 827-828, 2005 | 246 | 2005 |