Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (6508), eabc8511, 2020 | 1467 | 2020 |
Comprehensive mapping of immune perturbations associated with severe COVID-19 L Kuri-Cervantes, MB Pampena, W Meng, AM Rosenfeld, CAG Ittner, ... Science immunology 5 (49), eabd7114, 2020 | 768 | 2020 |
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern RR Goel, MM Painter, SA Apostolidis, D Mathew, W Meng, AM Rosenfeld, ... Science 374 (6572), abm0829, 2021 | 736 | 2021 |
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination RR Goel, SA Apostolidis, MM Painter, D Mathew, A Pattekar, O Kuthuru, ... Science immunology 6 (58), eabi6950, 2021 | 645 | 2021 |
Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy SA Apostolidis, M Kakara, MM Painter, RR Goel, D Mathew, K Lenzi, ... Nature medicine 27 (11), 1990-2001, 2021 | 442 | 2021 |
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer EM Bange, NA Han, P Wileyto, JY Kim, S Gouma, J Robinson, ... Nature medicine 27 (7), 1280-1289, 2021 | 425 | 2021 |
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection EM Anderson, EC Goodwin, A Verma, CP Arevalo, MJ Bolton, ME Weirick, ... Cell 184 (7), 1858-1864. e10, 2021 | 399 | 2021 |
Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination MM Painter, D Mathew, RR Goel, SA Apostolidis, A Pattekar, O Kuthuru, ... Immunity 54 (9), 2133-2142. e3, 2021 | 381 | 2021 |
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 205 | 2021 |
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine RR Goel, MM Painter, KA Lundgreen, SA Apostolidis, AE Baxter, JR Giles, ... Cell 185 (11), 1875-1887. e8, 2022 | 166 | 2022 |
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency JE Walter, LB Rosen, K Csomos, JM Rosenberg, D Mathew, M Keszei, ... The Journal of clinical investigation 125 (11), 4135-4148, 2015 | 166 | 2015 |
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation MS Abdel-Hakeem, S Manne, JC Beltra, E Stelekati, Z Chen, K Nzingha, ... Nature immunology 22 (8), 1008-1019, 2021 | 148 | 2021 |
SARS-CoV-2 seroprevalence among parturient women in Philadelphia DD Flannery, S Gouma, MB Dhudasia, S Mukhopadhyay, MR Pfeifer, ... Science immunology 5 (49), eabd5709, 2020 | 145 | 2020 |
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ... Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012 | 132 | 2012 |
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer Z Chen, E Arai, O Khan, Z Zhang, SF Ngiow, Y He, H Huang, S Manne, ... Cell 184 (5), 1262-1280. e22, 2021 | 125 | 2021 |
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions D Mathew, JR Giles, AE Baxter, AR Greenplate, JE Wu, C Alanio, ... BioRxiv, 2020 | 113 | 2020 |
UPenn COVID Processing Unit, MR Betts, NJ Meyer, EJ Wherry, Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (6508), 2020 | 107 | 2020 |
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ... Nature immunology 23 (11), 1600-1613, 2022 | 84 | 2022 |
Autoimmunity due to RAG deficiency and estimated disease incidence in RAG1/2 mutations K Chen, W Wu, D Mathew, Y Zhang, SK Browne, LB Rosen, MP McManus, ... Journal of Allergy and Clinical Immunology 133 (3), 880-882. e10, 2014 | 64 | 2014 |
LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling D Mathew, KN Kremer, P Strauch, G Tigyi, R Pelanda, RM Torres Frontiers in immunology 10, 1159, 2019 | 61 | 2019 |