Kit regulates HSC engraftment across the human-mouse species barrier KN Cosgun, S Rahmig, N Mende, S Reinke, I Hauber, C Schäfer, ... Cell stem cell 15 (2), 227-238, 2014 | 192 | 2014 |
Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity J Karpinski, I Hauber, J Chemnitz, C Schäfer, M Paszkowski-Rogacz, ... Nature biotechnology 34 (4), 401-409, 2016 | 164 | 2016 |
Targeted HIV-1 latency reversal using CRISPR/Cas9-derived transcriptional activator systems JK Bialek, GA Dunay, M Voges, C Schäfer, M Spohn, R Stucka, J Hauber, ... PloS one 11 (6), e0158294, 2016 | 96 | 2016 |
Humanized mouse models for the study of human malaria parasite biology, pathogenesis, and immunity NK Minkah, C Schafer, SHI Kappe Frontiers in immunology 9, 807, 2018 | 70 | 2018 |
A replication-competent late liver stage–attenuated human malaria parasite D Goswami, W Betz, NK Locham, C Parthiban, C Brager, C Schäfer, ... JCI insight 5 (13), 2020 | 51 | 2020 |
Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of … L Foquet, C Schafer, NK Minkah, DGW Alanine, EL Flannery, RWJ Steel, ... Frontiers in immunology 9, 524, 2018 | 48 | 2018 |
A humanized mouse model for Plasmodium vivax to test interventions that block liver stage to blood stage transition and blood stage infection C Schäfer, W Roobsoong, N Kangwanrangsan, M Bardelli, TA Rawlinson, ... IScience 23 (8), 2020 | 40 | 2020 |
A novel marker, ARM58, confers antimony resistance to Leishmania spp. A Nühs, C Schäfer, D Zander, L Trübe, PT Nevado, S Schmidt, J Arevalo, ... International Journal for Parasitology: Drugs and Drug Resistance 4 (1), 37-47, 2014 | 37 | 2014 |
A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages C Schafer, N Dambrauskas, RW Steel, S Carbonetti, V Chuenchob, ... Malaria journal 17, 1-10, 2018 | 33 | 2018 |
Plasmodium vivax Latent Liver Stage Infection and Relapse: Biological Insights and New Experimental Tools C Schäfer, G Zanghi, AM Vaughan, SHI Kappe Annual Review of Microbiology 75 (1), 87-106, 2021 | 28 | 2021 |
Assessing drug efficacy against Plasmodium falciparum liver stages in vivo EL Flannery, L Foquet, V Chuenchob, M Fishbaugher, Z Billman, ... JCI insight 3 (1), 2018 | 28 | 2018 |
Partial protection against P. vivax infection diminishes hypnozoite burden and blood-stage relapses C Schäfer, N Dambrauskas, LM Reynolds, O Trakhimets, A Raappana, ... Cell Host & Microbe 29 (5), 752-756. e4, 2021 | 22 | 2021 |
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine EL Flannery, N Kangwanrangsan, V Chuenchob, W Roobsoong, ... Molecular Therapy-Methods & Clinical Development 26, 427-440, 2022 | 18 | 2022 |
Reduced Antimony Accumulation in ARM58-Overexpressing Leishmania infantum C Schäfer, P Tejera Nevado, D Zander, J Clos Antimicrobial agents and chemotherapy 58 (3), 1565-1574, 2014 | 12 | 2014 |
Mass spectrometry identification of biomarkers in extracellular vesicles from Plasmodium vivax liver hypnozoite infections M Gualdrón-López, M Díaz-Varela, G Zanghi, I Aparici-Herraiz, RWJ Steel, ... Molecular & Cellular Proteomics 21 (10), 2022 | 11 | 2022 |
ARM58 overexpression reduces intracellular antimony concentration in Leishmania infantum C Schäfer, P Tejera Nevado, D Zander, J Clos Antimicrob Agents Chemother 58, 1565-1574, 2014 | 6 | 2014 |
Next-generation LTR-specific Tre-recombinase targets a majority of HIV-1 isolates J Hauber, J Karpinski, I Hauber, J Chemnitz, H Hofmann-Sieber, ... BMC Infectious Diseases 14, 1-1, 2014 | 1 | 2014 |
Personalizing humanized mice with cells obtained from an HIV post treatment controller I Hauber, JS Wiesch, U Schuhmacher, C Schäfer, J van Lunzen, J Hauber BMC Infectious Diseases 14, 1-1, 2014 | 1 | 2014 |
O5 CRISPR/Cas9-derived activation systems as new tools for induction of latent human immunodeficiency virus (HIV) JK Bialek, M Voges, GA Dunay, C Schäfer, M Spohn, J Hauber, UC Lange Journal of Virus Eradication 2, 2, 2016 | | 2016 |
G-107 Pronounced antiviral activity of next-generation LTR-specific Tre-recombinase C Schäfer, J Karpinski, I Hauber, J Chemnitz, H Hofmann-Sieber, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 67, 70, 2014 | | 2014 |