Extracellular vesicle and particle biomarkers define multiple human cancers A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ... Cell 182 (4), 1044-1061. e18, 2020 | 791 | 2020 |
p53: protection against tumor growth beyond effects on cell cycle and apoptosis X Wang, ER Simpson, KA Brown Cancer research 75 (23), 5001-5007, 2015 | 304 | 2015 |
Anti-Müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells L Pellatt, S Rice, N Dilaver, A Heshri, R Galea, M Brincat, K Brown, ... Fertility and sterility 96 (5), 1246-1251. e1, 2011 | 293 | 2011 |
Cyclooxygenase-2 and its role in ovulation: a 2004 account J Sirois, K Sayasith, KA Brown, AE Stock, N Bouchard, M Doré Human reproduction update 10 (5), 373-385, 2004 | 247 | 2004 |
Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression P Bhardwaj, CMC Au, A Benito-Martin, H Ladumor, S Oshchepkova, ... The Journal of steroid biochemistry and molecular biology 189, 161-170, 2019 | 178 | 2019 |
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2 M Reiterer, M Rajan, N Gómez-Banoy, JD Lau, LG Gomez-Escobar, L Ma, ... Cell metabolism 33 (11), 2174-2188. e5, 2021 | 177 | 2021 |
Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase KA Brown, NI Hunger, M Docanto, ER Simpson Breast cancer research and treatment 123, 591-596, 2010 | 164 | 2010 |
Obesity and breast cancer: progress to understanding the relationship KA Brown, ER Simpson Cancer research 70 (1), 4-7, 2010 | 160 | 2010 |
High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium CW Huo, G Chew, P Hill, D Huang, W Ingman, L Hodson, KA Brown, ... Breast Cancer Research 17, 1-20, 2015 | 159 | 2015 |
Metabolic obesity, adipose inflammation and elevated breast aromatase in women with normal body mass index NM Iyengar, KA Brown, XK Zhou, A Gucalp, K Subbaramaiah, DD Giri, ... Cancer Prevention Research 10 (4), 235-243, 2017 | 146 | 2017 |
Expression of key prostaglandin synthases in equine endometrium during late diestrus and early pregnancy D Boerboom, KA Brown, D Vaillancourt, P Poitras, AK Goff, K Watanabe, ... Biology of reproduction 70 (2), 391-399, 2004 | 141 | 2004 |
Obesity and breast cancer–Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue C Gerard, KA Brown Molecular and cellular endocrinology 466, 15-30, 2018 | 136 | 2018 |
Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer X Wang, ER Simpson, KA Brown The Journal of steroid biochemistry and molecular biology 153, 35-44, 2015 | 124 | 2015 |
Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in … KA Brown, KJ McInnes, NI Hunger, JS Oakhill, GR Steinberg, ER Simpson Cancer research 69 (13), 5392-5399, 2009 | 123 | 2009 |
Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer H Zahid, ER Simpson, KA Brown Current opinion in pharmacology 31, 90-96, 2016 | 113 | 2016 |
Minireview: obesity and breast cancer: a tale of inflammation and dysregulated metabolism ER Simpson, KA Brown Molecular endocrinology 27 (5), 715-725, 2013 | 112 | 2013 |
Obesity and breast cancer: role of inflammation and aromatase ER Simpson, KA Brown Journal of molecular endocrinology 51 (3), T51-T59, 2013 | 107 | 2013 |
Metabolic pathways in obesity-related breast cancer KA Brown Nature Reviews Endocrinology 17 (6), 350-363, 2021 | 106 | 2021 |
Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation, and systemic markers KA Brown, NM Iyengar, XK Zhou, A Gucalp, K Subbaramaiah, H Wang, ... The Journal of Clinical Endocrinology & Metabolism 102 (5), 1692-1701, 2017 | 100 | 2017 |
Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny W Lee, J Johnson, DJ Gough, J Donoghue, GLM Cagnone, V Vaghjiani, ... Cell death & disease 6 (2), e1664-e1664, 2015 | 94 | 2015 |