Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate EL Laviad, L Albee, I Pankova-Kholmyansky, S Epstein, H Park, ... Journal of Biological Chemistry 283 (9), 5677-5684, 2008 | 552 | 2008 |
Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers [S] RL Shaner, JC Allegood, H Park, E Wang, S Kelly, CA Haynes, ... Journal of lipid research 50 (8), 1692-1707, 2009 | 449 | 2009 |
A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways Y Pewzner-Jung, H Park, EL Laviad, LC Silva, S Lahiri, J Stiban, ... Journal of Biological Chemistry 285 (14), 10902-10910, 2010 | 391* | 2010 |
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides … NC Zitomer, T Mitchell, KA Voss, GS Bondy, ST Pruett, ... Journal of biological chemistry 284 (8), 4786-4795, 2009 | 260 | 2009 |
Subcellular organelle lipidomics in TLR-4-activated macrophages 1 [S] AY Andreyev, E Fahy, Z Guan, S Kelly, X Li, JG McDonald, S Milne, ... Journal of lipid research 51 (9), 2785-2797, 2010 | 215 | 2010 |
Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-de pend ent manner S Lahiri, H Park, EL Laviad, X Lu, R Bittman, AH Futerman Journal of Biological Chemistry 284 (24), 16090-16098, 2009 | 154 | 2009 |
Sphingolipidomics: methods for the comprehensive analysis of sphingolipids CA Haynes, JC Allegood, H Park, MC Sullards Journal of Chromatography B 877 (26), 2696-2708, 2009 | 153 | 2009 |
Structure‐Specific, quantitative methods for analysis of sphingolipids by liquid Chromatography–Tandem mass spectrometry:“Inside‐Out” sphingolipidomics MC Sullards, JC Allegood, S Kelly, E Wang, CA Haynes, H Park, Y Chen, ... Methods in enzymology 432, 83-115, 2007 | 153 | 2007 |
Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease AH Merrill, TH Stokes, A Momin, H Park, BJ Portz, S Kelly, E Wang, ... Journal of Lipid Research 50, S97-S102, 2009 | 141 | 2009 |
Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons N Hagen, PP Van Veldhoven, RL Proia, H Park, AH Merrill, ... Journal of Biological Chemistry 284 (17), 11346-11353, 2009 | 108 | 2009 |
The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche I Visigalli, S Ungari, S Martino, H Park, M Cesani, B Gentner, L Sergi Sergi, ... Blood, The Journal of the American Society of Hematology 116 (11), 1857-1866, 2010 | 62 | 2010 |
The Mutation Matters: CSF Profiles of GCase, Sphingolipids, α‐Synuclein in PDGBA S Lerche, C Schulte, I Wurster, G Machetanz, B Roeben, M Zimmermann, ... Movement Disorders 36 (5), 1216-1228, 2021 | 55 | 2021 |
Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons N Hagen-Euteneuer, D Lütjohann, H Park, AH Merrill, ... Journal of Biological Chemistry 287 (12), 9128-9136, 2012 | 53 | 2012 |
Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies [S] H Park, CA Haynes, AV Nairn, M Kulik, S Dalton, K Moremen, AH Merrill Journal of lipid research 51 (3), 480-489, 2010 | 42 | 2010 |
Direct analysis of sialylated or sulfated glycosphingolipids and other polar and neutral lipids using TLC-MS interfaces [S] H Park, Y Zhou, CE Costello Journal of Lipid Research 55 (4), 773-781, 2014 | 41 | 2014 |
Substrate reduction therapy for sandhoff disease through inhibition of glucosylceramide synthase activity J Marshall, JB Nietupski, H Park, J Cao, DS Bangari, C Silvescu, T Wilper, ... Molecular Therapy 27 (8), 1495-1506, 2019 | 35 | 2019 |
Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells SAF Morad, MC Messner, JC Levin, N Abdelmageed, H Park, AH Merrill, ... Cancer chemotherapy and pharmacology 71, 635-645, 2013 | 31 | 2013 |
De novo ceramide synthesis is required for N-linked glycosylation in plasma cells M Goldfinger, EL Laviad, R Hadar, M Shmuel, A Dagan, H Park, ... The Journal of Immunology 182 (11), 7038-7047, 2009 | 31 | 2009 |
Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI YE Huh, H Park, MSR Chiang, I Tuncali, G Liu, JJ Locascio, J Shirvan, ... npj Parkinson's Disease 7 (1), 102, 2021 | 29 | 2021 |
A method for visualization of “omic” datasets for sphingolipid metabolism to predict potentially interesting differences [S] AA Momin, H Park, BJ Portz, CA Haynes, RL Shaner, SL Kelly, IK Jordan, ... Journal of lipid research 52 (6), 1073-1083, 2011 | 28 | 2011 |