| Sustained proliferation in cancer: Mechanisms and novel therapeutic targets MA Feitelson, A Arzumanyan, RJ Kulathinal, SW Blain, RF Holcombe, ... Seminars in cancer biology 35, S25-S54, 2015 | 778 | 2015 |
| Exendin‐4, a glucagon‐like protein‐1 (GLP‐1) receptor agonist, reverses hepatic steatosis in ob/ob mice X Ding, NK Saxena, S Lin, N Gupta, FA Anania Hepatology 43 (1), 173-181, 2006 | 681 | 2006 |
| Glucagon‐like peptide‐1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the … NA Gupta, J Mells, RM Dunham, A Grakoui, J Handy, NK Saxena, ... Hepatology 51 (5), 1584-1592, 2010 | 585 | 2010 |
| Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells NK Saxena, D Sharma, X Ding, S Lin, F Marra, D Merlin, FA Anania Cancer research 67 (6), 2497-2507, 2007 | 583 | 2007 |
| Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates ofob/obmice NK Saxena, K Ikeda, DC Rockey, SL Friedman, FA Anania Hepatology 35 (4), 762-771, 2002 | 536 | 2002 |
| The roles of leptin and adiponectin: a novel paradigm in adipocytokine regulation of liver fibrosis and stellate cell biology X Ding, NK Saxena, S Lin, A Xu, S Srinivasan, FA Anania The American journal of pathology 166 (6), 1655-1669, 2005 | 364 | 2005 |
| GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy S Sharma, JE Mells, PP Fu, NK Saxena, FA Anania PloS one 6 (9), e25269, 2011 | 322 | 2011 |
| Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation NK Saxena, MA Titus, X Ding, J Floyd, S Srinivasan, SV Sitaraman, ... The FASEB journal: official publication of the Federation of American …, 2004 | 320 | 2004 |
| Designing a broad-spectrum integrative approach for cancer prevention and treatment KI Block, C Gyllenhaal, L Lowe, A Amedei, ARMR Amin, A Amin, ... Seminars in cancer biology 35, S276-S304, 2015 | 310 | 2015 |
| Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 NK Saxena, PM Vertino, FA Anania, D Sharma Journal of Biological Chemistry 282 (18), 13316-13325, 2007 | 245 | 2007 |
| Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways D Sharma, NK Saxena, PM Vertino, FA Anania Endocrine-related cancer 13 (2), 629-640, 2006 | 245 | 2006 |
| Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet JE Mells, PP Fu, S Sharma, D Olson, L Cheng, JA Handy, NK Saxena, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (2 …, 2012 | 240 | 2012 |
| Restoration of tamoxifen sensitivity in estrogen receptor–negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes D Sharma, NK Saxena, NE Davidson, PM Vertino Cancer research 66 (12), 6370-6378, 2006 | 235 | 2006 |
| Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth … NK Saxena, LT Taliaferro-Smith, BB Knight, D Merlin, FA Anania, ... Cancer research 68 (23), 9712-9722, 2008 | 232 | 2008 |
| Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3-and MTA1/Wnt1 protein-dependent pathways D Yan, D Avtanski, NK Saxena, D Sharma Journal of biological chemistry 287 (11), 8598-8612, 2012 | 224 | 2012 |
| Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis D Sharma, J Wang, PP Fu, S Sharma, A Nagalingam, J Mells, J Handy, ... Hepatology 52 (5), 1713-1722, 2010 | 217 | 2010 |
| Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis K Bhalla, BJ Hwang, RE Dewi, W Twaddel, OG Goloubeva, KK Wong, ... Cancer prevention research 5 (4), 544-552, 2012 | 197 | 2012 |
| LKB1 is required for adiponectin-mediated modulation of AMPK–S6K axis and inhibition of migration and invasion of breast cancer cells L Taliaferro-Smith, A Nagalingam, D Zhong, W Zhou, NK Saxena, ... Oncogene 28 (29), 2621-2633, 2009 | 194 | 2009 |
| ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis SJ Chung, GP Nagaraju, A Nagalingam, N Muniraj, P Kuppusamy, ... Autophagy 13 (8), 1386-1403, 2017 | 175 | 2017 |
| Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma NK Saxena, PP Fu, A Nagalingam, J Wang, J Handy, C Cohen, ... Gastroenterology 139 (5), 1762-1773. e5, 2010 | 171 | 2010 |
