Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ... Cancer cell 7 (1), 77-85, 2005 | 2340 | 2005 |
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing RD Guzy, B Hoyos, E Robin, H Chen, L Liu, KD Mansfield, MC Simon, ... Cell metabolism 1 (6), 401-408, 2005 | 1710 | 2005 |
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases NA Barlev, L Liu, NH Chehab, K Mansfield, KG Harris, TD Halazonetis, ... Molecular cell 8 (6), 1243-1254, 2001 | 899 | 2001 |
Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-α activation KD Mansfield, RD Guzy, Y Pan, RM Young, TP Cash, PT Schumacker, ... Cell metabolism 1 (6), 393-399, 2005 | 741 | 2005 |
Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro Y Pan, KD Mansfield, CC Bertozzi, V Rudenko, DA Chan, AJ Giaccia, ... Molecular and cellular biology 27 (3), 912-925, 2007 | 385 | 2007 |
Matrix regulation of skeletal cell apoptosis: role of calcium and phosphate ions CS Adams, K Mansfield, RL Perlot, IM Shapiro Journal of Biological Chemistry 276 (23), 20316-20322, 2001 | 246 | 2001 |
Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism K Mansfield, CC Teixeira, CS Adams, IM Shapiro Bone 28 (1), 1-8, 2001 | 157 | 2001 |
Extracellular phosphate ions cause apoptosis of terminally differentiated epiphyseal chondrocytes K Mansfield, R Rajpurohit, IM Shapiro Journal of cellular physiology 179 (3), 276-286, 1999 | 144 | 1999 |
Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation KD Mansfield, JD Keene Nucleic acids research 40 (6), 2734-2746, 2012 | 131 | 2012 |
Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species KD Mansfield, MC Simon, B Keith Journal of Applied Physiology 97 (4), 1358-1366, 2004 | 122 | 2004 |
The ribonome: a dominant force in co‐ordinating gene expression KD Mansfield, JD Keene Biology of the Cell 101 (3), 169-181, 2009 | 119 | 2009 |
N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs NJ Fry, BA Law, OR Ilkayeva, CL Holley, KD Mansfield Rna 23 (9), 1444-1455, 2017 | 107 | 2017 |
Induction of apoptosis in human T-cells by organomercuric compounds: a flow cytometric analysis BJ Shenker, S Datar, K Mansfield, IM Shapiro Toxicology and applied pharmacology 143 (2), 397-406, 1997 | 100 | 1997 |
Induction of apoptosis in skeletal tissues: phosphate-mediated chick chondrocyte apoptosis is calcium dependent K Mansfield, B Pucci, CS Adams, IM Shapiro Calcified tissue international 73, 161-172, 2003 | 82 | 2003 |
Chondrocyte death is linked to development of a mitochondrial membrane permeability transition in the growth plate R Rajpurohit, K Mansfield, K Ohyama, D Ewert, IM Shapiro Journal of cellular physiology 179 (3), 287-296, 1999 | 82 | 1999 |
RNA methyltransferase METTL16: Targets and function ER Satterwhite, KD Mansfield Wiley Interdisciplinary Reviews: RNA 13 (2), e1681, 2022 | 72 | 2022 |
Phosphate-induced chondrocyte apoptosis is linked to nitric oxide generation CC Teixeira, K Mansfield, C Hertkorn, H Ischiropoulos, IM Shapiro American Journal of Physiology-Cell Physiology 281 (3), C833-C839, 2001 | 70 | 2001 |
Characterization of METTL16 as a cytoplasmic RNA binding protein DJ Nance, ER Satterwhite, B Bhaskar, S Misra, KR Carraway, ... PLoS One 15 (1), e0227647, 2020 | 57 | 2020 |
Chondrocytes in the endochondral growth cartilage are not hypoxic IM Shapiro, KD Mansfield, SM Evans, EM Lord, CJ Koch American Journal of Physiology-Cell Physiology 272 (4), C1134-C1143, 1997 | 57 | 1997 |
Matrix regulation of skeletal cell apoptosis II: role of Arg‐Gly‐Asp‐containing peptides RL Perlot Jr, IM Shapiro, K Mansfield, CS Adams Journal of Bone and Mineral Research 17 (1), 66-76, 2002 | 49 | 2002 |