| Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains SJ Zost, K Parkhouse, ME Gumina, K Kim, S Diaz Perez, PC Wilson, ... Proceedings of the National Academy of Sciences 114 (47), 12578-12583, 2017 | 537 | 2017 |
| The kinetic stability of MHC class II: peptide complexes is a key parameter that dictates immunodominance CA Lazarski, FA Chaves, SA Jenks, S Wu, KA Richards, JM Weaver, ... Immunity 23 (1), 29-40, 2005 | 268 | 2005 |
| Revealing the role of CD4+ T cells in viral immunity AJ Sant, A McMichael Journal of Experimental Medicine 209 (8), 1391-1395, 2012 | 225 | 2012 |
| SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans PA Mudd, AA Minervina, MV Pogorelyy, JS Turner, W Kim, E Kalaidina, ... Cell 185 (4), 603-613. e15, 2022 | 213 | 2022 |
| MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells S Huang, S Gilfillan, S Kim, B Thompson, X Wang, AJ Sant, DH Fremont, ... The Journal of experimental medicine 205 (5), 1201-1211, 2008 | 165 | 2008 |
| The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II: peptide complexes AJ Sant, FA Chaves, SA Jenks, KA Richards, P Menges, JM Weaver, ... Immunological reviews 207 (1), 261-278, 2005 | 145 | 2005 |
| The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent. CC Stebbins, GE Loss Jr, CG Elias, A Chervonsky, AJ Sant The Journal of experimental medicine 181 (1), 223-234, 1995 | 129 | 1995 |
| MHC class II antigen processing: biology of invariant chain AJ Sant, J Miller Current opinion in immunology 6 (1), 57-63, 1994 | 129 | 1994 |
| Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules. JF Katz, C Stebbins, E Appella, AJ Sant The Journal of experimental medicine 184 (5), 1747-1753, 1996 | 121 | 1996 |
| Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan. AJ Sant, SE Cullen, KS Giacoletto, BD Schwartz The Journal of experimental medicine 162 (6), 1916-1934, 1985 | 105 | 1985 |
| Invariant chain retains MHC class II molecules in the endocytic pathway. GE Loss, AJ Sant The Journal of Immunology 150 (8), 3187-3197, 1993 | 100 | 1993 |
| Cutting edge: CD4 T cells generated from encounter with seasonal influenza viruses and vaccines have broad protein specificity and can directly recognize naturally generated … KA Richards, D Topham, FA Chaves, AJ Sant The Journal of Immunology 185 (9), 4998-5002, 2010 | 99 | 2010 |
| The impact of DM on MHC class II–restricted antigen presentation can be altered by manipulation of MHC–peptide kinetic stability CA Lazarski, FA Chaves, AJ Sant The Journal of experimental medicine 203 (5), 1319-1328, 2006 | 92 | 2006 |
| DM determines the cryptic and immunodominant fate of T cell epitopes NK Nanda, AJ Sant The Journal of experimental medicine 192 (6), 781-788, 2000 | 91 | 2000 |
| Ovalbumin(323−339) Peptide Binds to the Major Histocompatibility Complex Class II I-Ad Protein Using Two Functionally Distinct Registers BJ McFarland, AJ Sant, TP Lybrand, C Beeson Biochemistry 38 (50), 16663-16670, 1999 | 87 | 1999 |
| Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans S Khurana, M Hahn, EM Coyle, LR King, TL Lin, J Treanor, A Sant, ... Nature communications 10 (1), 1-15, 2019 | 85 | 2019 |
| Infection of HLA-DR1 transgenic mice with a human isolate of influenza a virus (H1N1) primes a diverse CD4 T-cell repertoire that includes CD4 T cells with heterosubtypic cross … KA Richards, FA Chaves, AJ Sant Journal of virology 83 (13), 6566-6577, 2009 | 85 | 2009 |
| Cutting edge: a single, essential hydrogen bond controls the stability of peptide-MHC class II complexes BJ McFarland, C Beeson, AJ Sant The Journal of Immunology 163 (7), 3567-3571, 1999 | 85 | 1999 |
| CD4+ T-Cell Expansion Predicts Neutralizing Antibody Responses to Monovalent, Inactivated 2009 Pandemic Influenza A(H1N1) Virus Subtype H1N1 Vaccine JL Nayak, TF Fitzgerald, KA Richards, H Yang, JJ Treanor, AJ Sant The Journal of infectious diseases 207 (2), 297-305, 2013 | 83 | 2013 |
| Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza … KA Richards, FA Chaves, FR Krafcik, DJ Topham, CA Lazarski, AJ Sant Journal of virology 81 (14), 7608-7619, 2007 | 83 | 2007 |
