| First toxicity report of tetrodotoxin and 5, 6, 11-trideoxyTTX in the trumpet shell Charonia lampas lampas in Europe P Rodriguez, A Alfonso, C Vale, C Alfonso, P Vale, A Tellez, LM Botana Analytical chemistry 80 (14), 5622-5629, 2008 | 188 | 2008 |
| First Detection of Tetrodotoxin in Greek Shellfish by UPLC-MS/MS Potentially Linked to the Presence of the Dinoflagellate Prorocentrum minimum A Vlamis, P Katikou, I Rodriguez, V Rey, A Alfonso, A Papazachariou, ... Toxins 7 (5), 1779-1807, 2015 | 180 | 2015 |
| First toxin profile of ciguateric fish in Madeira Arquipelago (Europe) P Otero, S Perez, A Alfonso, C Vale, P Rodríguez, NN Gouveia, ... Analytical chemistry 82 (14), 6032-6039, 2010 | 166 | 2010 |
| Modulation of cytosolic calcium levels of human lymphocytes by yessotoxin, a novel marine phycotoxin☆ LA de la Rosa, A Alfonso, N Vilariño, MR Vieytes, LM Botana Biochemical Pharmacology 61 (7), 827-833, 2001 | 158 | 2001 |
| Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity: effect of yessotoxin on cAMP levels in human lymphocytes A Alfonso, L de la Rosa, MR Vieytes, T Yasumoto, LM Botana Biochemical pharmacology 65 (2), 193-208, 2003 | 155 | 2003 |
| An overview of the effective combination therapies for the treatment of breast cancer C Núñez, JL Capelo, G Igrejas, A Alfonso, LM Botana, C Lodeiro Biomaterials 97, 34-50, 2016 | 140 | 2016 |
| New gastropod vectors and tetrodotoxin potential expansion in temperate waters of the Atlantic Ocean M Silva, J Azevedo, P Rodriguez, A Alfonso, LM Botana, V Vasconcelos Marine drugs 10 (4), 712-726, 2012 | 125 | 2012 |
| Liquid chromatography–mass spectrometry method to detect Tetrodotoxin and Its analogues in the puffer fish Lagocephalus sceleratus (Gmelin, 1789) from European waters P Rodríguez, A Alfonso, P Otero, P Katikou, D Georgantelis, LM Botana Food Chemistry 132 (2), 1103-1111, 2012 | 120 | 2012 |
| Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets Y Román, A Alfonso, MC Louzao, LA de la Rosa, F Leira, JM Vieites, ... Cellular Signalling 14 (8), 703-716, 2002 | 109 | 2002 |
| Calcium pools, calcium entry, and cell growth DL Gill, RT Waldron, KE Rys-Sikora, CA Ufret-Vincenty, MN Graber, ... Bioscience reports 16, 139-157, 1996 | 98 | 1996 |
| Functional compartments in rat mast cells for cAMP and calcium on histamine release A Alfonso, AG Cabado, MR Vieytes, LM Botana Cellular Signalling 12 (5), 343-350, 2000 | 96 | 2000 |
| Characterization of F-actin depolymerization as a major toxic event induced by pectenotoxin-6 in neuroblastoma cells F Leira, AG Cabado, MR Vieytes, Y Roman, A Alfonso, LM Botana, ... Biochemical pharmacology 63 (11), 1979-1988, 2002 | 92 | 2002 |
| A QuEChERS based extraction procedure coupled to UPLC-MS/MS detection for mycotoxins analysis in beer JM González-Jartín, A Alfonso, I Rodríguez, MJ Sainz, MR Vieytes, ... Food chemistry 275, 703-710, 2019 | 91 | 2019 |
| In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction C Vale, A Alfonso, MR Vieytes, XM Romarís, F Arevalo, AM Botana, ... Analytical Chemistry 80 (5), 1770-1776, 2008 | 89 | 2008 |
| Phycotoxins: chemistry and biochemistry LM Botana, A Alfonso John Wiley & Sons, 2015 | 88 | 2015 |
| Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes A Alfonso, Y Román, MR Vieytes, K Ofuji, M Satake, T Yasumoto, ... Biochemical pharmacology 69 (11), 1627-1636, 2005 | 88 | 2005 |
| Solid-phase radioreceptor assay for paralytic shellfish toxins MR Vieytes, AG Cabado, A Alfonso, MC Louzao, AM Botana, LM Botana Analytical biochemistry 211 (1), 87-93, 1993 | 88 | 1993 |
| Effects of Azaspiracid-1, A Potent Cytotoxic Agent, on Primary Neuronal Cultures. A Structure− Activity Relationship Study C Vale, KC Nicolaou, MO Frederick, B Gómez-Limia, A Alfonso, ... Journal of medicinal chemistry 50 (2), 356-363, 2007 | 85 | 2007 |
| Seafood intoxication by tetrodotoxin: First case in Europe JF Fernández-Ortega, JM Morales-de los Santos, ME Herrera-Gutiérrez, ... The Journal of emergency medicine 39 (5), 612-617, 2010 | 82 | 2010 |
| Antioxidant and Neuroprotective Potential of the Brown Seaweed Bifurcaria bifurcata in an in vitro Parkinson’s Disease Model J Silva, C Alves, R Freitas, A Martins, S Pinteus, J Ribeiro, H Gaspar, ... Marine drugs 17 (2), 85, 2019 | 77 | 2019 |
