Tumor Site–Specific Silencing of NF-κB p65 by Targeted Hollow Gold Nanosphere–Mediated Photothermal TransfectionSilencing of NF-κB p65 by Photothermal Transfection W Lu, G Zhang, R Zhang, LG Flores, Q Huang, JG Gelovani, C Li Cancer research 70 (8), 3177-3188, 2010 | 295 | 2010 |
Camptothecin derivative-loaded poly (caprolactone-co-lactide)-b-PEG-b-poly (caprolactone-co-lactide) nanoparticles and their biodistribution in mice L Zhang, Y Hu, X Jiang, C Yang, W Lu, YH Yang Journal of controlled release 96 (1), 135-148, 2004 | 214 | 2004 |
Synthesis and anti-hepatitis B virus activity of novel benzimidazole derivatives YF Li, GF Wang, PL He, WG Huang, FH Zhu, HY Gao, W Tang, Y Luo, ... Journal of medicinal chemistry 49 (15), 4790-4794, 2006 | 195 | 2006 |
Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics S Gao, G Wei, S Zhang, B Zheng, J Xu, G Chen, M Li, S Song, W Fu, ... Nature Communications 10 (1), 2206, 2019 | 186 | 2019 |
Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo M Huang, H Gao, Y Chen, H Zhu, Y Cai, X Zhang, Z Miao, H Jiang, ... Clinical cancer research 13 (4), 1298-1307, 2007 | 121 | 2007 |
Gold-based magneto/optical nanostructures: challenges for in vivo applications in cancer diagnostics and therapy MP Melancon, W Lu, C Li MRS bulletin 34 (6), 415-421, 2009 | 117 | 2009 |
Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins M Huang, ZH Miao, H Zhu, YJ Cai, W Lu, J Ding Molecular cancer therapeutics 7 (6), 1440-1449, 2008 | 91 | 2008 |
Celastrol acts as a potent antimetastatic agent targeting β1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase … H Zhu, XW Liu, TY Cai, J Cao, CX Tu, W Lu, QJ He, B Yang Journal of Pharmacology and Experimental Therapeutics 334 (2), 489-499, 2010 | 80 | 2010 |
Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors X Zhang, Y Kong, J Zhang, M Su, Y Zhou, Y Zang, J Li, Y Chen, Y Fang, ... European Journal of Medicinal Chemistry 95, 127-135, 2015 | 78 | 2015 |
Up-regulation of death receptor 4 and 5 by celastrol enhances the anti-cancer activity of TRAIL/Apo-2L H Zhu, XW Liu, WJ Ding, DQ Xu, YC Zhao, W Lu, QJ He, B Yang Cancer letters 297 (2), 155-164, 2010 | 71 | 2010 |
The discovery of colchicine-SAHA hybrids as a new class of antitumor agents X Zhang, J Zhang, L Tong, Y Luo, M Su, Y Zang, J Li, W Lu, Y Chen Bioorganic & medicinal chemistry 21 (11), 3240-3244, 2013 | 70 | 2013 |
Total synthesis of camptothecin and SN-38 S Yu, QQ Huang, Y Luo, W Lu The Journal of Organic Chemistry 77 (1), 713-717, 2012 | 70 | 2012 |
Stereoselective Total Synthesis of (3R,8S)-Falcarindiol, a Common Polyacetylenic Compound from Umbellifers G Zheng, W Lu, J Cai Journal of natural products 62 (4), 626-628, 1999 | 69 | 1999 |
Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol H Zhu, WJ Ding, R Wu, QJ Weng, JS Lou, RJ Jin, W Lu, B Yang, QJ He Cancer investigation 28 (1), 23-32, 2010 | 67 | 2010 |
Synthesis and biological evaluation of (±)-cryptotanshinone and its simplified analogues as potent CDC25 inhibitors WG Huang, YY Jiang, Q Li, J Li, JY Li, W Lu, JC Cai Tetrahedron 61 (7), 1863-1870, 2005 | 64 | 2005 |
High affinity of chlorin e6 to immunoglobulin G for intraoperative fluorescence image-guided cancer photodynamic and checkpoint blockade therapy J Xu, S Yu, X Wang, Y Qian, W Wu, S Zhang, B Zheng, G Wei, S Gao, ... ACS nano 13 (9), 10242-10260, 2019 | 63 | 2019 |
Synthesis and in vitro cytotoxic evaluation of some thiazolylbenzimidazole derivatives Y Luo, F Xiao, S Qian, W Lu, B Yang European journal of medicinal chemistry 46 (1), 417-422, 2011 | 63 | 2011 |
Neuronal mitochondria-targeted micelles relieving oxidative stress for delayed progression of Alzheimer's disease P Yang, D Sheng, Q Guo, P Wang, S Xu, K Qian, Y Li, Y Cheng, L Wang, ... Biomaterials 238, 119844, 2020 | 60 | 2020 |
Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines DY Lu, M Huang, CH Xu, WY Yang, CX Hu, LP Lin, LJ Tong, MH Li, W Lu, ... BMC pharmacology 5, 1-11, 2005 | 59 | 2005 |
10-Boronic acid substituted camptothecin as prodrug of SN-38 L Wang, S Xie, L Ma, Y Chen, W Lu European journal of medicinal chemistry 116, 84-89, 2016 | 58 | 2016 |