| Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2 D Riendeau, MD Percival, C Brideau, S Charleson, D Dube, D Ethier, ... Journal of Pharmacology and Experimental Therapeutics 296 (2), 558-566, 2001 | 640 | 2001 |
| The discovery of rofecoxib,[MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2 (5H)-furanone], an orally active cyclooxygenase-2 inhibitor P Prasit, Z Wang, C Brideau, CC Chan, S Charleson, W Cromlish, ... Bioorganic & medicinal chemistry letters 9 (13), 1773-1778, 1999 | 528 | 1999 |
| Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles CC Chan, S Boyce, C Brideau, S Charleson, W Cromlish, D Ethier, ... Journal of Pharmacology and Experimental Therapeutics 290 (2), 551-560, 1999 | 507 | 1999 |
| Induction of cyclooxygenase-2 and activation of nuclear factor-κB in myocardium of patients with congestive heart failure SCY Wong, M Fukuchi, P Melnyk, I Rodger, A Giaid Circulation 98 (2), 100-103, 1998 | 401 | 1998 |
| Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor D Riendeau, MD Percival, S Boyce, C Brideau, S Charleson, W Cromlish, ... British journal of pharmacology 121 (1), 105-117, 1997 | 385 | 1997 |
| A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors C Brideau, S Kargman, S Liu, AL Dallob, EW Ehrich, IW Rodger, CC Chan Inflammation Research 45, 68-74, 1996 | 361 | 1996 |
| Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4 receptor antagonist TR Jones, M Labelle, M Belley, E Champion, L Charette, J Evans, ... Canadian journal of physiology and pharmacology 73 (2), 191-201, 1995 | 305 | 1995 |
| Asthma: basic mechanisms and clinical management PJ Barnes, IW Rodger, NC Thomson Elsevier, 1998 | 236 | 1998 |
| Structure: action relationships among some desacetoxy analogues of pancuronium and vecuronium in the anesthetized cat. WC Bowman, IW Rodger, J Houston, RJ Marshall, I McIndewar Anesthesiology 69 (1), 57-62, 1988 | 226 | 1988 |
| Co-localization of the Cysteine Protease Caspase-3 with Apoptotic Myocytes afterIn VivoMyocardial Ischemia and Reperfusion in the Rat SC Black, JQ Huang, P Rezaiefar, S Radinovic, A Eberhart, ... Journal of molecular and cellular cardiology 30 (4), 733-742, 1998 | 225 | 1998 |
| Prostaglandin H synthase 2 expression in airway cells from patients with asthma and chronic obstructive pulmonary disease R Taha, RON Olivenstein, T Utsumi, P Ernst, PJ Barnes, IW Rodger, ... American journal of respiratory and critical care medicine 161 (2), 636-640, 2000 | 127 | 2000 |
| Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret A Robichaud, FD Tattersall, I Choudhury, IW Rodger Neuropharmacology 38 (2), 289-297, 1999 | 121 | 1999 |
| Comparison of in vivo airway responsiveness and in vitro smooth muscle sensitivity to methacholine in man. JA Roberts, D Raeburn, IW Rodger, NC Thomson Thorax 39 (11), 837-843, 1984 | 118 | 1984 |
| A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis J Zacher, D Feldman, R Gerli, D Scott, SM Hou, D Uebelhart, IW Rodger, ... Current medical research and opinion 19 (8), 725-736, 2003 | 108 | 2003 |
| Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways M McKenniff, IW Rodger, P Norman, PJ Gardiner European journal of pharmacology 153 (2-3), 149-159, 1988 | 100 | 1988 |
| Inhibition of cyclooxygenase-2 improves cardiac function in myocardial infarction T Saito, IW Rodger, F Hu, H Shennib, A Giaid Biochemical and biophysical research communications 273 (2), 772-775, 2000 | 95 | 2000 |
| The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung F Burns, IW Rodger, NJ Pyne Biochemical journal 283 (2), 487-491, 1992 | 94 | 1992 |
| Increased airway responsiveness to inhaled methacholine in a rat model of chronic bronchitis. S Shore, L Kobzik, NC Long, W Skornik, CJ Van Staden, L Boulet, ... American journal of respiratory and critical care medicine 151 (6), 1931-1938, 1995 | 86 | 1995 |
| Inhibition of COX pathway in experimental myocardial infarction T Saito, IW Rodger, F Hu, R Robinson, T Huynh, A Giaid Journal of molecular and cellular cardiology 37 (1), 71-77, 2004 | 82 | 2004 |
| L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats S Boyce, CC Chan, R Gordon, CS Li, IW Rodger, JK Webb, NMJ Rupniak, ... Neuropharmacology 33 (12), 1609-1611, 1994 | 80 | 1994 |
