Reducing protein oxidation reverses lung fibrosis V Anathy, KG Lahue, DG Chapman, SB Chia, DT Casey, R Aboushousha, ... Nature medicine 24 (8), 1128-1135, 2018 | 104 | 2018 |
IL-1/inhibitory κB kinase ε–induced glycolysis augment epithelial effector function and promote allergic airways disease X Qian, R Aboushousha, C van de Wetering, SB Chia, E Amiel, ... Journal of Allergy and Clinical Immunology 142 (2), 435-450. e10, 2018 | 51 | 2018 |
Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases SB Chia, EA Elko, R Aboushousha, AM Manuel, C van de Wetering, ... American Journal of Physiology-Cell Physiology 318 (2), C304-C327, 2020 | 42 | 2020 |
TRPV1 promotes opioid analgesia during inflammation L Basso, R Aboushousha, CY Fan, M Iftinca, H Melo, R Flynn, F Agosti, ... Science signaling 12 (575), eaav0711, 2019 | 42 | 2019 |
Targeting the transient receptor potential vanilloid type 1 (TRPV1) assembly domain attenuates inflammation-induced hypersensitivity R Flynn, K Chapman, M Iftinca, R Aboushousha, D Varela, C Altier Journal of Biological Chemistry 289 (24), 16675-16687, 2014 | 39 | 2014 |
Pyruvate Kinase M2 promotes expression of proinflammatory mediators in house dust mite–induced allergic airways disease C van De Wetering, R Aboushousha, AM Manuel, SB Chia, C Erickson, ... The Journal of Immunology 204 (4), 763-774, 2020 | 37 | 2020 |
Peroxiredoxins and beyond; redox systems regulating lung physiology and disease EA Elko, B Cunniff, DJ Seward, SB Chia, R Aboushousha, ... Antioxidants & Redox Signaling 31 (14), 1070-1091, 2019 | 36 | 2019 |
The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel M Iftinca, R Flynn, L Basso, H Melo, R Aboushousha, L Taylor, C Altier Molecular pain 12, 1744806916663945, 2016 | 25 | 2016 |
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2 C van de Wetering, AM Manuel, M Sharafi, R Aboushousha, X Qian, ... Redox Biology 47, 102160, 2021 | 22 | 2021 |
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells R Aboushousha, E Elko, SB Chia, AM Manuel, C van de Wetering, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 12 | 2021 |
A generative approach toward precision antimicrobial peptide design JB Ferrell, JM Remington, CM Van Oort, M Sharafi, R Aboushousha, ... BioRxiv, 2020.10. 02.324087, 2020 | 12 | 2020 |
Dysregulation of pyruvate kinase M2 promotes inflammation in a mouse model of obese allergic asthma AM Manuel, C van de Wetering, M MacPherson, C Erickson, C Murray, ... American Journal of Respiratory Cell and Molecular Biology 64 (6), 709-721, 2021 | 11 | 2021 |
Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling SB Chia, JD Nolin, R Aboushousha, C Erikson, CG Irvin, ME Poynter, ... Redox Biology 37, 101720, 2020 | 7 | 2020 |
S-Glutathionylation-Controlled Apoptosis of Lung Epithelial Cells; Potential Implications for Lung Fibrosis E Corteselli, R Aboushousha, Y Janssen-Heininger Antioxidants 11 (9), 1789, 2022 | 6 | 2022 |
Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system xC− R Aboushousha, J van der Velden, N Hamilton, Z Peng, M MacPherson, ... Science advances 9 (37), eadi5192, 2023 | 5 | 2023 |
S-glutathionylation of pyruvate kinase M2 is associated with metabolic reprogramming and cytokine production in the development of allergic obese airway disease A Manuel, X Qian, C van de Wetering, SB Chia, R Aboushousha, ... A21, Advances in Asthma Pathogenesis A 1048, 2019 | 2 | 2019 |
TRPV1 regulates opioid analgesia during inflammation L Basso, R Aboushousha, CY Fan, M Iftinca, H Melo, R Flynn, F Agosti, ... bioRxiv, 274233, 2018 | 1 | 2018 |
The glutathione S-transferase Gstt1 drives survival and dissemination in metastases CM Ferrer, HM Cho, R Boon, T Bernasocchi, LP Wong, M Cetinbas, ... Nature Cell Biology, 1-16, 2024 | | 2024 |
Impact of Expansion Medium on Progenitor Potential of Tracheospheres E Corteselli, JE Druso, R Aboushousha, M MacPherson, C Erickson, ... A71. CUTTING EDGE TECHNOLOGIES FOR LUNG DISCOVERY, A2562-A2562, 2024 | | 2024 |
Upregulation of Glutathione S Transferase P in Lung Epithelial Cells Augmentsinterleukin 1 Beta (IL1B)-induced Pro-inflammatory Signaling in Association With Oxidation of … YMW Janssen-Heininger, R Aboushousha, M MacPherson, ... A74. MITOCHONDRIA AND METABOLISM IN LUNG HEALTH AND DISEASE, A2607-A2607, 2024 | | 2024 |