Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound R Carlisle, J Choi, M Bazan-Peregrino, R Laga, V Subr, L Kostka, ... Journal of the National Cancer Institute 105 (22), 1701-1710, 2013 | 130 | 2013 |
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition L Vande Walle, IB Stowe, P Šácha, BL Lee, D Demon, A Fossoul, ... PLoS biology 17 (9), e3000354, 2019 | 108 | 2019 |
Coating of adenovirus type 5 with polymers containing quaternary amines prevents binding to blood components V Subr, L Kostka, T Selby-Milic, K Fisher, K Ulbrich, LW Seymour, ... Journal of controlled release 135 (2), 152-158, 2009 | 77 | 2009 |
HPMA copolymer-based nanomedicines in controlled drug delivery P Chytil, L Kostka, T Etrych Journal of Personalized Medicine 11 (2), 115, 2021 | 50 | 2021 |
Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: Impact of release rate on biodistribution P Chytil, S Hoffmann, L Schindler, L Kostka, K Ulbrich, H Caysa, T Mueller, ... Journal of controlled release 172 (2), 504-512, 2013 | 50 | 2013 |
Thermoresponsive Self‐Assembly of Short Elastin‐Like Polypentapeptides and Their Poly (ethylene glycol) Derivatives M Pechar, J Brus, L Kostka, Č Koňák, M Urbanová, M Šlouf Macromolecular bioscience 7 (1), 56-69, 2007 | 50 | 2007 |
Synthesis of Well-Defined Semitelechelic Poly[N-(2-hydroxypropyl)methacrylamide] Polymers with Functional Group at the α-End of the Polymer Chain by RAFT … V Subr, L Kostka, J Strohalm, T Etrych, K Ulbrich Macromolecules 46 (6), 2100-2108, 2013 | 43 | 2013 |
Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance A Braunová, L Kostka, L Sivák, L Cuchalová, Z Hvězdová, R Laga, ... Journal of controlled release 245, 41-51, 2017 | 42 | 2017 |
Hydrolytically degradable polymer micelles for anticancer drug delivery to solid tumors P Chytil, T Etrych, L Kostka, K Ulbrich Macromolecular Chemistry and Physics 213 (8), 858-867, 2012 | 41 | 2012 |
HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours L Kostka, L Kotrchová, V Šubr, A Libánská, CA Ferreira, I Malátová, ... Biomaterials 235, 119728, 2020 | 39 | 2020 |
Synthesis and properties of star HPMA copolymer nanocarriers synthesised by RAFT polymerisation designed for selective anticancer drug delivery and imaging P Chytil, E Koziolová, O Janoušková, L Kostka, K Ulbrich, T Etrych Macromolecular Bioscience 15 (6), 839-850, 2015 | 37 | 2015 |
HPMA Copolymer Conjugates of DOX and Mitomycin C for Combination Therapy: Physicochemical Characterization, Cytotoxic Effects, Combination Index Analysis, and Anti‐T umor Efficacy H Kostková, T Etrych, B Říhová, L Kostka, L Starovoytová, M Kovář, ... Macromolecular bioscience 13 (12), 1648-1660, 2013 | 37 | 2013 |
Inhibitor–GCPII interaction: selective and robust system for targeting cancer cells with structurally diverse nanoparticles J Neburkova, F Sedlak, J Zackova Suchanova, L Kostka, P Sacha, V Subr, ... Molecular Pharmaceutics 15 (8), 2932-2945, 2018 | 32 | 2018 |
Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo L Beckert, L Kostka, E Kessel, AK Levacic, H Kostkova, T Etrych, ... European Journal of Pharmaceutics and Biopharmaceutics 105, 85-96, 2016 | 30 | 2016 |
Inhibitor-decorated polymer conjugates targeting fibroblast activation protein P Dvořáková, P Bušek, T Knedlik, J Schimer, T Etrych, L Kostka, ... Journal of Medicinal Chemistry 60 (20), 8385-8393, 2017 | 29 | 2017 |
High-molecular-weight HPMA-based polymer drug carriers for delivery to tumor. L Kostka, T Etrych Physiological Research 65, 2016 | 28 | 2016 |
Coating of vesicles with hydrophilic reactive polymers C Koňák, V Šubr, L Kostka, P Štěpánek, K Ulbrich, H Schlaad Langmuir 24 (14), 7092-7098, 2008 | 27 | 2008 |
N-(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production E Koziolová, L Kostka, L Kotrchová, V Šubr, R Konefal, B Nottelet, ... Biomacromolecules 19 (10), 4003-4013, 2018 | 26 | 2018 |
Star Polymer‐Drug Conjugates with pH‐Controlled Drug Release and Carrier Degradation H Kostková, L Schindler, L Kotrchová, M Kovář, M Šírová, L Kostka, ... Journal of Nanomaterials 2017 (1), 8675435, 2017 | 18 | 2017 |
Micelle-forming block copolymers tailored for inhibition of P-gp-mediated multidrug resistance: structure to activity relationship A Braunová, M Kaňa, J Kudláčová, L Kostka, J Bouček, J Betka, M Šírová, ... Pharmaceutics 11 (11), 579, 2019 | 14 | 2019 |