Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat) L Ferreira, E Teixeira-de-Lemos, F Pinto, B Parada, C Mega, H Vala, ... Mediators of inflammation 2010 (1), 592760, 2010 | 293 | 2010 |
Methylglyoxal promotes oxidative stress and endothelial dysfunction CM Sena, P Matafome, J Crisóstomo, L Rodrigues, R Fernandes, ... Pharmacological Research 65 (5), 497-506, 2012 | 232 | 2012 |
Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis TM Ribeiro-Rodrigues, TL Laundos, R Pereira-Carvalho, ... Cardiovascular research 113 (11), 1338-1350, 2017 | 215 | 2017 |
Diabetic nephropathy amelioration by a low-dose sitagliptin in an animal model of type 2 diabetes (Zucker diabetic fatty rat) C Mega, E Teixeira de Lemos, H Vala, R Fernandes, J Oliveira, ... Journal of Diabetes Research 2011, 2011 | 205 | 2011 |
Metformin restores endothelial function in aorta of diabetic rats CM Sena, P Matafome, T Louro, E Nunes, R Fernandes, RM Seiça British journal of pharmacology 163 (2), 424-437, 2011 | 184 | 2011 |
The chaperone-dependent ubiquitin ligase CHIP targets HIF-1α for degradation in the presence of methylglyoxal CF Bento, R Fernandes, J Ramalho, C Marques, F Shang, A Taylor, ... PloS one 5 (11), e15062, 2010 | 159 | 2010 |
Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals C Marques, C Mega, A Gonçalves, P Rodrigues-Santos, ... Mediators of inflammation 2014 (1), 538737, 2014 | 145 | 2014 |
Effects of α‐lipoic acid on endothelial function in aged diabetic and high‐fat fed rats CM Sena, E Nunes, T Louro, T Proença, R Fernandes, MR Boarder, ... British Journal of Pharmacology 153 (5), 894-906, 2008 | 137 | 2008 |
Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy R Fernandes, SD Viana, S Nunes, F Reis Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (7 …, 2019 | 131 | 2019 |
Porphyrin conjugated with serum albumins and monoclonal antibodies boosts efficiency in targeted destruction of human bladder cancer cells PMR Pereira, JJ Carvalho, S Silva, JAS Cavaleiro, RJ Schneider, ... Organic & biomolecular chemistry 12 (11), 1804-1811, 2014 | 131 | 2014 |
High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism R Fernandes, H Girao, P Pereira Journal of Biological Chemistry 279 (26), 27219-27224, 2004 | 126 | 2004 |
The place of dipeptidyl peptidase‐4 inhibitors in type 2 diabetes therapeutics: A “me too” or “the special one” antidiabetic class? R Godinho, C Mega, E Teixeira-de-Lemos, E Carvalho, F Teixeira, ... Journal of diabetes research 2015 (1), 806979, 2015 | 109 | 2015 |
Amphiphilic phthalocyanine–cyclodextrin conjugates for cancer photodynamic therapy LMO Lourenço, PMR Pereira, E Maciel, M Válega, FMJ Domingues, ... Chemical Communications 50 (61), 8363-8366, 2014 | 109 | 2014 |
Photodynamic inactivation of Penicillium chrysogenum conidia by cationic porphyrins MC Gomes, SM Woranovicz-Barreira, MAF Faustino, R Fernandes, ... Photochemical & Photobiological Sciences 10, 1735-1743, 2011 | 109 | 2011 |
Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood–retinal barrier in a type 2 diabetes animal model A Gonçalves, E Leal, A Paiva, E Teixeira Lemos, F Teixeira, CF Ribeiro, ... Diabetes, Obesity and Metabolism 14 (5), 454-463, 2012 | 104 | 2012 |
Regulation of claudins in blood-tissue barriers under physiological and pathological states A Gonçalves, AF Ambrósio, R Fernandes Tissue barriers 1 (3), e24782, 2013 | 95 | 2013 |
Adiponectin improves endothelial function in mesenteric arteries of rats fed a high‐fat diet: role of perivascular adipose tissue CM Sena, A Pereira, R Fernandes, L Letra, RM Seiça British journal of pharmacology 174 (20), 3514-3526, 2017 | 92 | 2017 |
Phthalocyanine Thio‐Pyridinium Derivatives as Antibacterial Photosensitizers† JB Pereira, EFA Carvalho, MAF Faustino, R Fernandes, MG Neves, ... Photochemistry and Photobiology 88 (3), 537-547, 2012 | 84 | 2012 |
Dipeptidyl peptidase-IV inhibition prevents blood–retinal barrier breakdown, inflammation and neuronal cell death in the retina of type 1 diabetic rats A Gonçalves, C Marques, E Leal, CF Ribeiro, F Reis, AF Ambrósio, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014 | 81 | 2014 |
Downregulation of retinal GLUT1 in diabetes by ubiquitinylation R Fernandes, AL Carvalho, A Kumagai, R Seica, K Hosoya, T Terasaki, ... Molecular Vision, 2004 | 80 | 2004 |