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Alexander Hanzl
Alexander Hanzl
CeMM
在 cemm.at 的电子邮件经过验证
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Selective Mediator dependence of cell-type-specifying transcription
MG Jaeger, B Schwalb, SD Mackowiak, T Velychko, A Hanzl, H Imrichova, ...
Nature genetics 52 (7), 719-727, 2020
712020
Plasticity of the Cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation
C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ...
Molecular cell 75 (4), 849-858. e8, 2019
702019
Targeted protein degradation: current and future challenges
A Hanzl, GE Winter
Current opinion in chemical biology 56, 35-41, 2020
562020
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells
J Ferreira da Silva, S Salic, M Wiedner, P Datlinger, P Essletzbichler, ...
Scientific Reports 9 (1), 1-10, 2019
142019
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders
A Hanzl, R Casement, H Imrichova, SJ Hughes, E Barone, A Testa, ...
Nature chemical biology 19 (3), 323-333, 2023
132023
Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders
A Hanzl, R Casement, H Imrichova, SJ Hughes, E Barone, A Testa, ...
BioRxiv, 2022.04. 14.488316, 2022
32022
E3-specific degrader discovery by dynamic tracing of substrate receptor abundance
A Hanzl, E Barone, S Bauer, H Yue, RP Nowak, E Hahn, EV Pankevich, ...
Journal of the American Chemical Society 145 (2), 1176-1184, 2023
22023
Neue Krebstherapien: Resistenzen vorbeugen und überwinden
A Hanzl
TumorDiagn u Ther 44, 2023
2023
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