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Bo Kyung Alex Seong
Bo Kyung Alex Seong
Dana-Farber Cancer Institute
在 dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
B Nabet, FM Ferguson, BKA Seong, M Kuljanin, AL Leggett, ML Mohardt, ...
Nature communications 11 (1), 4687, 2020
1502020
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma
BKA Seong, NV Dharia, S Lin, KA Donovan, S Chong, A Robichaud, ...
Cancer cell 39 (9), 1262-1278. e7, 2021
622021
SATB2 enhances migration and invasion in osteosarcoma by regulating genes involved in cytoskeletal organization
BKA Seong, J Lau, T Adderley, L Kee, D Chaukos, M Pienkowska, ...
Oncogene 34 (27), 3582-3592, 2015
562015
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ...
Cancer cell 39 (6), 827-844. e10, 2021
542021
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML
S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, M Kuljanin, ...
Cancer discovery 12 (2), 432-449, 2022
432022
A metastatic mouse model identifies genes that regulate neuroblastoma metastasis
BKA Seong, KE Fathers, R Hallett, CK Yung, LD Stein, S Mouaaz, L Kee, ...
Cancer research 77 (3), 696-706, 2017
392017
Biology and therapy of dominant fusion oncoproteins involving transcription factor and chromatin regulators in sarcomas
JA Perry, BKA Seong, K Stegmaier
Annual Review of Cancer Biology 3, 299-321, 2019
322019
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma
B Jiang, J Jiang, IH Kaltheuner, AB Iniguez, K Anand, FM Ferguson, ...
European Journal of Medicinal Chemistry 221, 113481, 2021
312021
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma
DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ...
Nature Cell Biology 25 (2), 285-297, 2023
182023
Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma
RM Hallett, ABK Seong, DR Kaplan, MS Irwin
Molecular oncology 10 (9), 1461-1472, 2016
142016
Gene fusions create partner and collateral dependencies essential to cancer cell survival
R Gillani, BKA Seong, J Crowdis, JR Conway, NV Dharia, S Alimohamed, ...
Cancer research 81 (15), 3971-3984, 2021
132021
Vitamin D receptor activation attenuates hippo pathway effectors and cell survival in metastatic neuroblastoma
Y Ladumor, BKA Seong, R Hallett, I Valencia-Sama, T Adderley, Y Wang, ...
Molecular Cancer Research 20 (6), 895-908, 2022
42022
The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients
A Alshareef, MS Irwin, N Gupta, HF Zhang, M Haque, SD Findlay, ...
Oncotarget 9 (12), 10698, 2018
22018
SLC5A3 Transports Myo-Inositol to Support the Growth of Acute Myeloid Leukemia
S Lin, NK Scheidegger, G Alexe, BKA Seong, NV Dharia, C Wechsler, ...
Blood 138, 3319, 2021
12021
EWS-FLI1-driven upregulation of UGT3A2 unlocks drug sensitivity pathway in Ewing sarcoma
O Olaoye, C Harrington, K Ross, BKA Seong, L de Waal, J Qi, J Roth, ...
Cancer Research 84 (6_Supplement), 3244-3244, 2024
2024
Abstract B021: Long non-coding RNAs that are required for robust cell growth in ewing Sarcoma
MC Briones Martin del Campo, A Lee, M Horlbeck, T Dinh, ...
Clinical Cancer Research 28 (18_Supplement), B021-B021, 2022
2022
An In Vivo CRISPR Screening Platform to Identify New Therapeutic Targets in AML
S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, C Wechsler, ...
Blood 138, 266, 2021
2021
STAG2 loss reshapes oncogenic enhancer-promoter looping in Ewing sarcoma
B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ...
Elsevier BV, 2021
2021
Abstract B50: Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma
BKA Seong, S Lin, K Donovan, A Robichaud, B Stolte, E Wang, N Dharia, ...
Cancer Research 80 (14_Supplement), B50-B50, 2020
2020
Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma
BKA Seong, S Lin, K Donovan, A Robichaud, B Stolte, E Wang, N Dharia, ...
CANCER RESEARCH 80 (14), 105-106, 2020
2020
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