Swarm learning for decentralized and confidential clinical machine learning S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ... Nature 594 (7862), 265-270, 2021 | 598 | 2021 |
β-Glucan reverses the epigenetic state of LPS-induced immunological tolerance B Novakovic, E Habibi, SY Wang, RJW Arts, R Davar, W Megchelenbrink, ... Cell 167 (5), 1354-1368. e14, 2016 | 559 | 2016 |
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016 | 524 | 2016 |
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity MF Osuchowski, MS Winkler, T Skirecki, S Cajander, M Shankar-Hari, ... The Lancet Respiratory Medicine 9 (6), 622-642, 2021 | 493 | 2021 |
Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans M Kox, LT Van Eijk, J Zwaag, J Van Den Wildenberg, FCGJ Sweep, ... Proceedings of the National Academy of Sciences 111 (20), 7379-7384, 2014 | 369 | 2014 |
Cytokine levels in critically ill patients with COVID-19 and other conditions M Kox, NJB Waalders, EJ Kooistra, J Gerretsen, P Pickkers Jama 324 (15), 1565-1567, 2020 | 352 | 2020 |
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 303 | 2020 |
Current gaps in sepsis immunology: new opportunities for translational research I Rubio, MF Osuchowski, M Shankar-Hari, T Skirecki, MS Winkler, ... The Lancet infectious diseases 19 (12), e422-e436, 2019 | 291 | 2019 |
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ... Cell metabolism 29 (1), 211-220. e5, 2019 | 289 | 2019 |
Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change? J Leentjens, M Kox, JG van der Hoeven, MG Netea, P Pickkers American journal of respiratory and critical care medicine 187 (12), 1287-1293, 2013 | 287 | 2013 |
BCG vaccination enhances the immunogenicity of subsequent influenza vaccination in healthy volunteers: a randomized, placebo-controlled pilot study J Leentjens, M Kox, R Stokman, J Gerretsen, DA Diavatopoulos, ... The Journal of infectious diseases 212 (12), 1930-1938, 2015 | 263 | 2015 |
Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series CE Delsing, MS Gresnigt, J Leentjens, F Preijers, FA Frager, M Kox, ... BMC infectious diseases 14, 1-12, 2014 | 257 | 2014 |
Reversal of immunoparalysis in humans in vivo: a double-blind, placebo-controlled, randomized pilot study J Leentjens, M Kox, RM Koch, F Preijers, LAB Joosten, ... American journal of respiratory and critical care medicine 186 (9), 838-845, 2012 | 255 | 2012 |
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients AC Aschenbrenner, M Mouktaroudi, B Krämer, M Oestreich, N Antonakos, ... Genome medicine 13, 1-25, 2021 | 236 | 2021 |
IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1 S de Kleijn, JD Langereis, J Leentjens, M Kox, MG Netea, L Koenderman, ... PloS one 8 (8), e72249, 2013 | 227 | 2013 |
Biomarkers associated with delirium in critically ill patients and their relation with long-term subjective cognitive dysfunction; indications for different pathways governing … M Van den Boogaard, M Kox, KL Quinn, T van Achterberg, ... Critical care 15, 1-9, 2011 | 225 | 2011 |
Enteroendocrine L cells sense LPS after gut barrier injury to enhance GLP-1 secretion LJ Lebrun, K Lenaerts, D Kiers, JPP de Barros, N Le Guern, J Plesnik, ... Cell reports 21 (5), 1160-1168, 2017 | 175 | 2017 |
Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients K Timmermans, M Kox, M Vaneker, M van den Berg, A John, ... Intensive care medicine 42, 551-561, 2016 | 164 | 2016 |
Sepsis-induced immunoparalysis: mechanisms, markers, and treatment options L Hamers, M Kox, P Pickkers Minerva anestesiol 81 (4), 426-39, 2015 | 161 | 2015 |
Precision immunotherapy for sepsis AM Peters van Ton, M Kox, WF Abdo, P Pickkers Frontiers in immunology 9, 1926, 2018 | 157 | 2018 |