Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ... Nature communications 11 (1), 3523, 2020 | 425 | 2020 |
CCL19 and CCR7 expression, signaling pathways, and adjuvant functions in viral infection and prevention Y Yan, R Chen, X Wang, K Hu, L Huang, M Lu, Q Hu Frontiers in cell and developmental biology 7, 212, 2019 | 138 | 2019 |
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice AJ Spencer, PF McKay, S Belij-Rammerstorfer, M Ulaszewska, CD Bissett, ... Nature communications 12 (1), 2893, 2021 | 132 | 2021 |
Big is beautiful: enhanced saRNA delivery and immunogenicity by a higher molecular weight, bioreducible, cationic polymer AK Blakney, Y Zhu, PF McKay, CR Bouton, J Yeow, J Tang, K Hu, ... ACS nano 14 (5), 5711-5727, 2020 | 130 | 2020 |
Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial KM Pollock, HM Cheeseman, AJ Szubert, V Libri, M Boffito, D Owen, ... EClinicalMedicine 44, 2022 | 103 | 2022 |
Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines AK Blakney, PF McKay, K Hu, K Samnuan, N Jain, A Brown, A Thomas, ... Journal of controlled release 338, 201-210, 2021 | 72 | 2021 |
DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein P Wang, K Hu, S Luo, M Zhang, X Deng, C Li, W Jin, B Hu, S He, M Li, ... Virology 488, 108-119, 2016 | 60 | 2016 |
Herpes simplex virus type 2 infection of human epithelial cells induces CXCL9 expression and CD4+ T cell migration via activation of p38-CCAAT/enhancer-binding protein-β pathway W Huang, K Hu, S Luo, M Zhang, C Li, W Jin, Y Liu, GE Griffin, ... The Journal of Immunology 188 (12), 6247-6257, 2012 | 58 | 2012 |
Highly conserved HIV-1 gp120 glycans proximal to CD4-binding region affect viral infectivity and neutralizing antibody induction X Huang, W Jin, K Hu, S Luo, T Du, GE Griffin, RJ Shattock, Q Hu Virology 423 (1), 97-106, 2012 | 54 | 2012 |
Innate inhibiting proteins enhance expression and immunogenicity of self-amplifying RNA AK Blakney, PF McKay, CR Bouton, K Hu, K Samnuan, RJ Shattock Molecular Therapy 29 (3), 1174-1185, 2021 | 53 | 2021 |
CCL19 and CCL28 augment mucosal and systemic immune responses to HIV-1 gp140 by mobilizing responsive immunocytes into secondary lymph nodes and mucosal tissue K Hu, S Luo, L Tong, X Huang, W Jin, W Huang, T Du, Y Yan, S He, ... The Journal of Immunology 191 (4), 1935-1947, 2013 | 50 | 2013 |
HSV-2 immediate-early protein US1 inhibits IFN-β production by suppressing association of IRF-3 with IFN-β promoter M Zhang, Y Liu, P Wang, X Guan, S He, S Luo, C Li, K Hu, W Jin, T Du, ... The Journal of Immunology 194 (7), 3102-3115, 2015 | 44 | 2015 |
Contribution of N-linked glycans on HSV-2 gB to cell–cell fusion and viral entry S Luo, K Hu, S He, P Wang, M Zhang, X Huang, T Du, C Zheng, Y Liu, ... Virology 483, 72-82, 2015 | 41 | 2015 |
Tick-borne encephalitis virus nonstructural protein NS5 induces RANTES expression dependent on the RNA-dependent RNA polymerase activity Z Zheng, J Yang, X Jiang, Y Liu, X Zhang, M Li, M Zhang, M Fu, K Hu, ... The Journal of Immunology 201 (1), 53-68, 2018 | 34 | 2018 |
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine induces equivalent preclinical antibody titers and viral neutralization to recovered COVID-19 patients PF McKay, K Hu, AK Blakney, K Samnuan, CR Bouton, P Rogers, K Polra, ... BioRXiv, 2020.04. 22.055608, 2020 | 28 | 2020 |
DC-SIGN plays a stronger role than DCIR in mediating HIV-1 capture and transfer W Jin, C Li, T Du, K Hu, X Huang, Q Hu Virology 458, 83-92, 2014 | 28 | 2014 |
Bifunctional CD4–DC-SIGN Fusion Proteins Demonstrate Enhanced Avidity to gp120 and Inhibit HIV-1 Infection and Dissemination T Du, K Hu, J Yang, J Jin, C Li, D Stieh, GE Griffin, RJ Shattock, Q Hu Antimicrobial agents and chemotherapy 56 (9), 4640-4649, 2012 | 27 | 2012 |
Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early … M Zhang, X Deng, X Guan, L Geng, M Fu, B Zhang, R Chen, H Hu, K Hu, ... Frontiers in immunology 9, 2932, 2018 | 20 | 2018 |
Immunization with HSV-2 gB-CCL19 fusion constructs protects mice against lethal vaginal challenge Y Yan, K Hu, X Deng, X Guan, S Luo, L Tong, T Du, M Fu, M Zhang, Y Liu, ... The Journal of Immunology 195 (1), 329-338, 2015 | 19 | 2015 |
Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice. Nat. Commun. 11, 3523 PF McKay, K Hu, AK Blakney, K Samnuan, JC Brown, R Penn, J Zhou, ... | 18 | 2020 |