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Simon Langer
Simon Langer
Scientist High-Throughput Biology and Screening bei Boehringer Ingelheim, Biberach an der Riss
在 boehringer-ingelheim.com 的电子邮件经过验证 - 首页
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The potency of Nef-mediated SERINC5 antagonism correlates with the prevalence of primate lentiviruses in the wild
A Heigele, D Kmiec, K Regensburger, S Langer, L Peiffer, CM Stürzel, ...
Cell host & microbe 20 (3), 381-391, 2016
1022016
FK506‐binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells
E Kaiser, N Böhm, K Ernst, S Langer, C Schwan, K Aktories, M Popoff, ...
Cellular microbiology 14 (8), 1193-1205, 2012
832012
Sensor sensibility—HIV-1 and the innate immune response
X Yin, S Langer, Z Zhang, KM Herbert, S Yoh, R König, SK Chanda
Cells 9 (1), 254, 2020
662020
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses
S Langer, C Hammer, K Hopfensperger, L Klein, D Hotter, PD De Jesus, ...
Elife 8, e41930, 2019
662019
HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression
S Srinivasachar Badarinarayan, I Shcherbakova, S Langer, L Koepke, ...
Nucleic Acids Research 48 (19), 10890-10908, 2020
632020
Cyclophilin-facilitated membrane translocation as pharmacological target to prevent intoxication of mammalian cells by binary clostridial actin ADP-ribosylated toxins
K Ernst, S Langer, E Kaiser, C Osseforth, J Michaelis, MR Popoff, ...
Journal of molecular biology 427 (6), 1224-1238, 2015
632015
The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
M Schuster, L Schnell, P Feigl, C Birkhofer, K Mohr, M Roeder, S Carle, ...
Scientific reports 7 (1), 613, 2017
492017
Human-specific adaptations in Vpu conferring anti-tetherin activity are critical for efficient early HIV-1 replication in vivo
E Yamada, S Nakaoka, L Klein, E Reith, S Langer, K Hopfensperger, ...
Cell host & microbe 23 (1), 110-120. e7, 2018
382018
Large-scale arrayed analysis of protein degradation reveals cellular targets for HIV-1 Vpu
P Jain, G Boso, S Langer, S Soonthornvacharin, PD De Jesus, Q Nguyen, ...
Cell reports 22 (9), 2493-2503, 2018
262018
Efficient Vpu-mediated tetherin antagonism by an HIV-1 group O strain
K Mack, K Starz, D Sauter, S Langer, F Bibollet-Ruche, GH Learn, ...
Journal of virology 91 (6), 10.1128/jvi. 02177-16, 2017
252017
Yersinia enterocolitica YopT and Clostridium difficile Toxin B Induce Expression of GILZ in Epithelial Cells
M Köberle, D Göppel, T Grandl, P Gaentzsch, B Manncke, S Berchtold, ...
PloS one 7 (7), e40730, 2012
192012
Unusual fusion proteins of HIV-1
S Langer, D Sauter
Frontiers in Microbiology 7, 238946, 2017
122017
The E3 ubiquitin-protein ligase cullin 3 regulates HIV-1 transcription
S Langer, X Yin, A Diaz, AJ Portillo, DE Gordon, UH Rogers, JM Marlett, ...
Cells 9 (9), 2010, 2020
82020
A Naturally Occurring rev1-vpu Fusion Gene Does Not Confer a Fitness Advantage to HIV-1
SM Langer, K Hopfensperger, SS Iyer, EF Kreider, GH Learn, LH Lee, ...
PLoS One 10 (11), e0142118, 2015
52015
671 Peeters M, Pizzato M, Learn GH, Hahn BH, Kirchhoff F. 2016. The Potency of Nef-672 Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate 673 Lentiviruses in …
A Heigele, D Kmiec, K Regensburger, S Langer, L Peiffer, CM Sturzel, ...
Cell Host Microbe 20, 381-391, 0
3
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor
CA Stoneham, S Langer, PD De Jesus, JM Wozniak, J Lapek, T Deerinck, ...
PLoS Pathogens 17 (11), e1009409, 2021
2021
Requirement of host cell factors Hsp90 and PPIases might be a common characteristic for cellular uptake of bacterial ADP-ribosylating toxins
K Ernst, S Langer, H Barth
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 386, S20-S20, 2013
2013
Author response: HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses
S Langer, C Hammer, K Hopfensperger, L Klein, D Hotter, PD De Jesus, ...
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