Reshaping human antibodies for therapy L Riechmann, M Clark, H Waldmann, G Winter Nature 332 (6162), 323-327, 1988 | 3622 | 1988 |
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. M Brüggemann, GT Williams, CI Bindon, MR Clark, MR Walker, R Jefferis, ... The Journal of experimental medicine 166 (5), 1351, 1987 | 1106 | 1987 |
Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H G Hale, MR Clark, R Marcus, G Winter, MJS Dyer, JM Phillips, ... The Lancet 332 (8625), 1394-1399, 1988 | 728 | 1988 |
Recombinant human IgG molecules lacking Fc receptor I binding and monocyte triggering activities KL Armour, MR Clark, AG Hadley, LM Williamson European journal of immunology 29, 2613-2624, 1999 | 537 | 1999 |
Antibody humanization: a case of the "Emperor's new clothes"? M Clark Immunology today 21 (8), 397-402, 2000 | 464 | 2000 |
IgG Effector Functions MR Clark Chemical immunology 65, 88-110, 1997 | 343* | 1997 |
The generation of a humanized, non‐mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties S Bolt, E Routledge, I Lloyd, L Chatenoud, H Pope, SD Gorman, M Clark, ... European journal of immunology 23 (2), 403-411, 1993 | 312 | 1993 |
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006 M Clark, JF Colombel, BC Feagan, RN Fedorak, SB Hanauer, MA Kamm, ... Gastroenterology 133 (1), 312-339, 2007 | 306 | 2007 |
Monoclonal-antibody therapy in systemic vasculitis PW Mathieson, SP Cobbold, G Hale, MR Clark, DBG Oliveira, ... New England Journal of Medicine 323 (4), 250-254, 1990 | 300 | 1990 |
Reshaping a therapeutic CD4 antibody SD Gorman, MR Clark, EG Routledge, SP Cobbold, H Waldmann Proceedings of the National Academy of Sciences 88 (10), 4181, 1991 | 245 | 1991 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldmann, ... US Patent 6,706,265, 2004 | 234* | 2004 |
Tolerance to rat monoclonal antibodies. Implications for serotherapy. RJ Benjamin, SP Cobbold, MR Clark, H Waldmann The Journal of experimental medicine 163 (6), 1539-1552, 1986 | 214 | 1986 |
Structural motifs involved in human IgG antibody effector functions J Greenwood, M Clark, H Waldmann European journal of immunology 23 (5), 1098-1104, 1993 | 213 | 1993 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman US Patent App. 11/300,396, 2005 | 204* | 2005 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldmann US Patent 5,585,097, 1996 | 204 | 1996 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman US Patent App. 11/501,894, 2006 | 201* | 2006 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman US Patent App. 10/743,423, 2003 | 198* | 2003 |
Humanized anti-CD3 specific antibodies S Bolt, M Clark, S Gorman, E Routledge, H Waldman US Patent App. 11/300,278, 2005 | 197* | 2005 |
Humanized anti-CD3 specific antibodies SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman US Patent App. 11/300,279, 2005 | 197* | 2005 |
Differential binding to human FcγRIIa and FcγRIIb receptors by human IgG wildtype and mutant antibodies KL Armour, JGJ van de Winkel, LM Williamson, MR Clark Molecular immunology 40 (9), 585-593, 2003 | 183 | 2003 |