Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential H Kheraldine, O Rachid, AM Habib, AE Al Moustafa, IF Benter, S Akhtar Advanced Drug Delivery Reviews 178, 113908, 2021 | 87 | 2021 |
Crosstalk between HER2 and PD-1/PD-L1 in breast cancer: from clinical applications to mathematical models R Padmanabhan, HS Kheraldine, N Meskin, S Vranic, AE Al Moustafa Cancers 12 (3), 636, 2020 | 53 | 2020 |
Elaeagnus angustifolia plant extract inhibits epithelial-mesenchymal transition and induces apoptosis via HER2 inactivation and JNK pathway in HER2-positive breast cancer cells A Jabeen, A Sharma, I Gupta, H Kheraldine, S Vranic, AE Al Moustafa, ... Molecules 25 (18), 4240, 2020 | 25 | 2020 |
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways H Kheraldine, I Gupta, H Alhussain, A Jabeen, FS Cyprian, S Akhtar, ... Computational and Structural Biotechnology Journal 19, 2881-2890, 2021 | 20 | 2021 |
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo M Al-Asmakh, H Bawadi, M Hamdan, I Gupta, H Kheraldine, A Jabeen, ... Biomedicine & Pharmacotherapy 134, 111134, 2021 | 11 | 2021 |
Significant Toxic Effect of Carbon Nanofibers at the Early Stage of Embryogenesis GG Abdo, H Kheraldine, I Gupta, B Rizeq, A Elzatahry, AE Al Moustafa, ... Journal of Biomedical Nanotechnology 16 (6), 975-984, 2020 | 10 | 2020 |
Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways B Rizeq, I Gupta, H Kheraldine, D Elkhalifa, HF Al-Farsi, AEA Moustafa, ... International journal of molecular sciences 22 (17), 9621, 2021 | 9 | 2021 |
Water-pipe smoking exposure deregulates a set of genes associated with human head and neck cancer development and prognosis VM López-Ozuna, I Gupta, RLC Kiow, E Matanes, H Kheraldine, ... Toxics 8 (3), 73, 2020 | 9 | 2020 |
Naked poly (amidoamine) dendrimer nanoparticles exhibit intrinsic embryotoxicity during the early stages of normal development H Kheraldine, I Gupta, H Alhussain, A Jabeen, S Akhtar, AE Al Moustafa, ... Journal of Biomedical Nanotechnology 16 (10), 1454-1462, 2020 | 7 | 2020 |
Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications SS Bashraheel, H Kheraldine, S Khalaf, AE Al Moustafa Biomedicine & Pharmacotherapy 162, 114676, 2023 | 6 | 2023 |
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor R Padmanabhan, H Kheraldine, I Gupta, N Meskin, A Hamad, S Vranic, ... Frontiers in Oncology 12, 977664, 2022 | 5 | 2022 |
The effect of surface-modified gold nanorods on the early stage of embryonic development and angiogenesis: Insight into the molecular pathways NN Mahmoud, ZZ Zakaria, H Kheraldine, I Gupta, S Vranic, M Al-Asmakh, ... International Journal of Molecular Sciences 22 (20), 11036, 2021 | 2 | 2021 |
Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways GG Abdo, I Gupta, H Kheraldine, B Rizeq, MM Zagho, A Khalil, ... Materials Science and Engineering: C 122, 111910, 2021 | 2 | 2021 |
Mathematical Modeling of the Growth Suppression of HER2+ Breast Cancer Colonies Under the Effect of Trastuzumab and PD-1/PD-L1 Inhibitor R Padmanabhan, H Kheraldine, I Gupta, N Meskin, A Hamad, S Vranic, ... Preprints, 2022 | 1 | 2022 |
Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways H Kheraldine, I Gupta, FS Cyprian, S Vranic, HF Al-Farsi, M Merhi, ... Cancer Cell International 24 (1), 1-15, 2024 | | 2024 |
Effects of neratinib on angiogenesis and the early stage of the embryo using chicken embryo as a model. H Kheraldine, AF Hassan, H Alhussein, H Al-Thawadi, S Vranic, ... the Association of Basic Medical Sciences, 2023 | | 2023 |
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo AA Maha, H Bawadi, M Hamdan, I Gupta, H Kheraldine, A Jabeen, ... Elsevier, 2021 | | 2021 |
The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast … H Kheraldine, I Gupta, F Cyprian, S Vranic, AE Al Moustafa Qatar University Press, 2021 | | 2021 |
Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells A Jabeen, A Sharma, I Gupta, H Kheraldine, S Vranic, AE Al Moustafa, ... MDPI, 2020 | | 2020 |
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis H Kheraldine | | 2020 |