Blood-brain barrier: from physiology to disease and back MD Sweeney, Z Zhao, A Montagne, AR Nelson, BV Zlokovic Physiological reviews, 2018 | 1559 | 2018 |
Establishment and dysfunction of the blood-brain barrier Z Zhao, AR Nelson, C Betsholtz, BV Zlokovic Cell 163 (5), 1064-1078, 2015 | 1421 | 2015 |
Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction DA Nation, MD Sweeney, A Montagne, AP Sagare, LM D’Orazio, ... Nature medicine 25 (2), 270-276, 2019 | 1202 | 2019 |
Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease K Kisler, AR Nelson, A Montagne, BV Zlokovic Nature Reviews Neuroscience 18 (7), 419-434, 2017 | 1060 | 2017 |
APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline A Montagne, DA Nation, AP Sagare, G Barisano, MD Sweeney, ... Nature 581 (7806), 71-76, 2020 | 883 | 2020 |
GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration EA Winkler, Y Nishida, AP Sagare, SV Rege, RD Bell, D Perlmutter, ... Nature neuroscience 18 (4), 521-530, 2015 | 604 | 2015 |
Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease AR Nelson, MD Sweeney, AP Sagare, BV Zlokovic Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (5), 887-900, 2016 | 576 | 2016 |
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 557 | 2018 |
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain K Kisler, AR Nelson, SV Rege, A Ramanathan, Y Wang, A Ahuja, D Lazic, ... Nature neuroscience 20 (3), 406-416, 2017 | 463 | 2017 |
Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1 A Ramanathan, AR Nelson, AP Sagare, BV Zlokovic Frontiers in aging neuroscience 7, 136, 2015 | 215 | 2015 |
O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses EW Taylor, K Wang, AR Nelson, TM Bredemann, KB Fraser, SM Clinton, ... Journal of Neuroscience 34 (1), 10-21, 2014 | 111 | 2014 |
Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology CC Smith, LC Vedder, AR Nelson, TM Bredemann, LL McMahon Proceedings of the National Academy of Sciences 107 (45), 19543-19548, 2010 | 101 | 2010 |
Role of clusterin in the brain vascular clearance of amyloid-β AR Nelson, AP Sagare, BV Zlokovic Proceedings of the National Academy of Sciences 114 (33), 8681-8682, 2017 | 85 | 2017 |
Channelrhodopsin Excitation Contracts Brain Pericytes and Reduces Blood Flow in the Aging Mouse Brain in vivo AR Nelson, MA Sagare, Y Wang, K Kisler, Z Zhao, BV Zlokovic Frontiers in aging neuroscience 12, 108, 2020 | 64 | 2020 |
Core labeling of adenovirus with EGFP LP Le, HN Le, AR Nelson, DA Matthews, M Yamamoto, DT Curiel Virology 351 (2), 291-302, 2006 | 30 | 2006 |
Noradrenergic sympathetic sprouting and cholinergic reinnervation maintains non-amyloidogenic processing of AβPP AR Nelson, K Kolasa, LL McMahon Journal of Alzheimer's Disease 38 (4), 867-879, 2014 | 24 | 2014 |
Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C AP Amar, AP Sagare, Z Zhao, Y Wang, AR Nelson, JH Griffin, BV Zlokovic Neuropharmacology 134, 293-301, 2018 | 23 | 2018 |
Combination of conditionally replicative adenovirus and standard chemotherapies shows synergistic antitumor effect in pancreatic cancer AR Nelson, J Davydova, DT Curiel, M Yamamoto Cancer science 100 (11), 2181-2187, 2009 | 22 | 2009 |
Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy CS Choi, M Gwin, S Voth, C Kolb, C Zhou, AR Nelson, A DeWeever, ... Journal of Biological Chemistry 298 (1), 2022 | 19 | 2022 |
Vascular cognitive impairment and dementia: An early career researcher perspective NCBS Silva, O Bracko, AR Nelson, FF de Oliveira, LS Robison, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 14 (1 …, 2022 | 14 | 2022 |