关注
Dharmin Rokad
Dharmin Rokad
Study Director, Covance/Labcorp Drug Development
在 labcorp.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease
S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ...
npj Parkinson's Disease 3 (1), 30, 2017
2382017
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ...
Journal of Experimental Medicine 216 (6), 1411-1430, 2019
2132019
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ...
Science signaling 12 (572), eaau4543, 2019
1522019
Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes
S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ...
Neurotoxicology 64, 204-218, 2018
1332018
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
S Sarkar, D Rokad, E Malovic, J Luo, DS Harischandra, H Jin, ...
Science Signaling 12 (563), eaat9900, 2019
1252019
Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease
S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ...
The Journal of Clinical Investigation 130 (8), 4195-4212, 2020
1072020
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events
N Singh, V Lawana, J Luo, P Phong, A Abdalla, B Palanisamy, D Rokad, ...
Neurobiology of disease 117, 82-113, 2018
1002018
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ...
Neurobiology of disease 93, 96-114, 2016
1002016
Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal …
DS Harischandra, S Ghaisas, D Rokad, M Zamanian, H Jin, ...
Neurotoxicology 64, 267-277, 2018
942018
Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation
D Rokad, S Ghaisas, DS Harischandra, H Jin, V Anantharam, ...
Brain research bulletin 133, 60-70, 2017
632017
Exosomes in toxicology: relevance to chemical exposure and pathogenesis of environmentally linked diseases
DS Harischandra, S Ghaisas, D Rokad, AG Kanthasamy
Toxicological Sciences 158 (1), 3-13, 2017
522017
Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease
DS Harischandra, D Rokad, S Ghaisas, S Verma, A Robertson, H Jin, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (4), 165533, 2020
312020
Characterization and comparative analysis of a new mouse microglial cell model for studying neuroinflammatory mechanisms during neurotoxic insults
S Sarkar, E Malovic, D Sarda, V Lawana, D Rokad, H Jin, V Anantharam, ...
Neurotoxicology 67, 129-140, 2018
312018
Exosomes as mediators of chemical-induced toxicity
D Rokad, H Jin, V Anantharam, A Kanthasamy, AG Kanthasamy
Current environmental health reports 6, 73-79, 2019
222019
Disruption of intracellular signaling
A Kanthasamy, J Luo, D Rokad, A Charli
An Introduction to Interdisciplinary Toxicology, 81-96, 2020
32020
Epitranscriptomic reader YTHDF2 regulates SEK1 (MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress
E Malovic, A Ealy, C Miller, A Jang, PJ Hsu, S Sarkar, D Rokad, C Goeser, ...
Iscience 27 (9), 2024
2024
Role of Manganese Toxicity on Endosomal Trafficking, Exosomal Proteins and Potential Biomarkers Identification for Parkinson’s Disease
DD Rokad
Iowa State University, 2020
2020
Manganese Exposure Induces the Release of Exosomes Containing Misfolded alpha-Synuclein by Impairing Endosomal Trafficking and Protein Degradation Machinery
DD Rokad, D Harischandra, D Luo, S Sarkar, VJ Lawana, D Kim, H Jin, ...
International Journal of Toxicology 39 (1), 48-48, 2020
2020
Role of neurotoxicants and traumatic brain injury in-synuclein protein misfolding and aggregation
D Rokad, S Ghaisas, DS Harischandra, H Jin, V Anantharam, ...
2016
系统目前无法执行此操作,请稍后再试。
文章 1–19