| Selectivity of 4, 5, 6, 7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (‘casein kinase-2’) S Sarno, H Reddy, F Meggio, M Ruzzene, SP Davies, A Donella-Deana, ... FEBS letters 496 (1), 44-48, 2001 | 411 | 2001 |
| Protein kinase CK2 phosphorylates and upregulates Akt/PKB G Di Maira, M Salvi, G Arrigoni, O Marin, S Sarno, F Brustolon, LA Pinna, ... Cell Death & Differentiation 12 (6), 668-677, 2005 | 374 | 2005 |
| The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks JI Loizou, SF El-Khamisy, A Zlatanou, DJ Moore, DW Chan, J Qin, ... Cell 117 (1), 17-28, 2004 | 366 | 2004 |
| The selectivity of inhibitors of protein kinase CK2: an update MA Pagano, J Bain, Z Kazimierczuk, S Sarno, M Ruzzene, G Di Maira, ... Biochemical Journal 415 (3), 353-365, 2008 | 269 | 2008 |
| Optimization of protein kinase CK2 inhibitors derived from 4, 5, 6, 7-tetrabromobenzimidazole MA Pagano, M Andrzejewska, M Ruzzene, S Sarno, L Cesaro, J Bain, ... Journal of medicinal chemistry 47 (25), 6239-6247, 2004 | 210 | 2004 |
| Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis M Salvi, S Sarno, L Cesaro, H Nakamura, LA Pinna Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (5), 847-859, 2009 | 205 | 2009 |
| Toward the rational design of protein kinase casein kinase-2 inhibitors S Sarno, S Moro, F Meggio, G Zagotto, D Dal Ben, P Ghisellini, ... Pharmacology & therapeutics 93 (2-3), 159-168, 2002 | 205 | 2002 |
| Structural features underlying selective inhibition of protein kinase CK2 by ATP site‐directed tetrabromo‐2‐benzotriazole R Battistutta, E De Moliner, S Sarno, G Zanotti, LA Pinna Protein Science 10 (11), 2200-2206, 2001 | 194 | 2001 |
| The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2 R Battistutta, S Sarno, E De Moliner, E Papinutto, G Zanotti, LA Pinna Journal of Biological Chemistry 275 (38), 29618-29622, 2000 | 188 | 2000 |
| Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application G Cozza, P Bonvini, E Zorzi, G Poletto, MA Pagano, S Sarno, ... Journal of medicinal chemistry 49 (8), 2363-2366, 2006 | 182 | 2006 |
| Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 G Cozza, M Mazzorana, E Papinutto, J Bain, M Elliott, G Di Maira, ... Biochemical Journal 421 (3), 387-395, 2009 | 175 | 2009 |
| Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer R Battistutta, G Cozza, F Pierre, E Papinutto, G Lolli, S Sarno, SE O’Brien, ... Biochemistry 50 (39), 8478-8488, 2011 | 167 | 2011 |
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5, 6-dihydroindolo-(1, 2-a) quinazolin-7-yl] acetic acid (IQA) S Sarno, E de Moliner, M Ruzzene, MA Pagano, R Battistutta, J Bain, ... Biochemical journal 374 (3), 639-646, 2003 | 166 | 2003 |
| Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight G Lolli, G Cozza, M Mazzorana, E Tibaldi, L Cesaro, A Donella-Deana, ... Biochemistry 51 (31), 6097-6107, 2012 | 163 | 2012 |
| Protein Kinase CK2 Mutants Defective in Substrate Recognition: PURIFICATION AND KINETIC ANALYSIS (∗) S Sarno, P Vaglio, F Meggio, OG Issinger, LA Pinna Journal of Biological Chemistry 271 (18), 10595-10601, 1996 | 147 | 1996 |
| Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole R Battistutta, M Mazzorana, S Sarno, Z Kazimierczuk, G Zanotti, LA Pinna Chemistry & biology 12 (11), 1211-1219, 2005 | 140 | 2005 |
| Protein kinase CK2 as a druggable target S Sarno, LA Pinna Molecular bioSystems 4 (9), 889-894, 2008 | 135 | 2008 |
| Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors MA Pagano, G Poletto, G Di Maira, G Cozza, M Ruzzene, S Sarno, J Bain, ... Chembiochem 8 (1), 129-139, 2007 | 134 | 2007 |
| CK2: a protein kinase in need of control B Guerra, B Boldyreff, S Sarno, L Cesaro, OG Issinger, LA Pinna Pharmacology & therapeutics 82 (2-3), 303-313, 1999 | 125 | 1999 |
| Specificity of the polycation‐stimulated (type‐2A) and ATP, Mg‐dependent (type‐1) protein phosphatases toward substrates phosphorylated by P34cdc2 kinase P Agostinis, R Derua, S Sarno, J Goris, W Merlevede European journal of biochemistry 205 (1), 241-248, 1992 | 123 | 1992 |
