Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve N Uemura, H Yagi, MT Uemura, Y Hatanaka, H Yamakado, R Takahashi Molecular neurodegeneration 13, 1-11, 2018 | 264 | 2018 |
Brain microvascular pericytes in vascular cognitive impairment and dementia MT Uemura, T Maki, M Ihara, VMY Lee, JQ Trojanowski Frontiers in aging neuroscience 12, 80, 2020 | 185 | 2020 |
Exercise Is More Effective than Diet Control in Preventing High Fat Diet-induced β-Amyloid Deposition and Memory Deficit in Amyloid Precursor Protein Transgenic Mice*♦ M Maesako, K Uemura, M Kubota, A Kuzuya, K Sasaki, N Hayashida, ... Journal of Biological Chemistry 287 (27), 23024-23033, 2012 | 160 | 2012 |
Cell-to-cell transmission of tau and α-synuclein N Uemura, MT Uemura, KC Luk, VMY Lee, JQ Trojanowski Trends in molecular medicine 26 (10), 936-952, 2020 | 112 | 2020 |
Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter T Maki, M Maeda, M Uemura, EK Lo, Y Terasaki, AC Liang, A Shindo, ... Neuroscience letters 597, 164-169, 2015 | 96 | 2015 |
α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson’s disease model T Taguchi, M Ikuno, M Hondo, LK Parajuli, K Taguchi, J Ueda, ... Brain 143 (1), 249-265, 2020 | 85 | 2020 |
Loss of capillary pericytes and the blood–brain barrier in white matter in poststroke and vascular dementias and Alzheimer’s disease R Ding, Y Hase, KE Ameen‐Ali, M Ndung'u, W Stevenson, J Barsby, ... Brain Pathology 30 (6), 1087-1101, 2020 | 73 | 2020 |
Copper enhances APP dimerization and promotes Aβ production Y Noda, M Asada, M Kubota, M Maesako, K Watanabe, M Uemura, ... Neuroscience letters 547, 10-15, 2013 | 67 | 2013 |
Slow progressive accumulation of oligodendroglial alpha-synuclein (α-syn) pathology in synthetic α-syn fibril-induced mouse models of synucleinopathy N Uemura, MT Uemura, A Lo, F Bassil, B Zhang, KC Luk, VMY Lee, ... Journal of Neuropathology & Experimental Neurology 78 (10), 877-890, 2019 | 54 | 2019 |
The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease K Watanabe, K Uemura, M Asada, M Maesako, H Akiyama, S Shimohama, ... Molecular brain 8, 1-14, 2015 | 51 | 2015 |
High fat diet enhances β-site cleavage of amyloid precursor protein (APP) via promoting β-site APP cleaving enzyme 1/adaptor protein 2/clathrin complex formation M Maesako, M Uemura, Y Tashiro, K Sasaki, K Watanabe, Y Noda, ... PloS one 10 (9), e0131199, 2015 | 45 | 2015 |
Continuation of exercise is necessary to inhibit high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice M Maesako, K Uemura, A Iwata, M Kubota, K Watanabe, M Uemura, ... PloS one 8 (9), e72796, 2013 | 43 | 2013 |
Pericyte‐derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion MT Uemura, M Ihara, T Maki, T Nakagomi, S Kaji, K Uemura, ... Brain Pathology 28 (4), 521-535, 2018 | 42 | 2018 |
α‐Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC‐SNCA Mice N Uemura, J Ueda, T Yoshihara, M Ikuno, MT Uemura, H Yamakado, ... Movement Disorders 36 (9), 2036-2047, 2021 | 40 | 2021 |
Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease MT Uemura, JL Robinson, KAQ Cousins, TF Tropea, DC Kargilis, ... Acta neuropathologica 143 (1), 15-31, 2022 | 33 | 2022 |
Zonisamide inhibits monoamine oxidase and enhances motor performance and social activity MT Uemura, T Asano, R Hikawa, H Yamakado, R Takahashi Neuroscience Research 124, 25-32, 2017 | 30 | 2017 |
Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract N Uemura, H Yagi, MT Uemura, H Yamakado, R Takahashi Neuroscience letters 716, 134651, 2020 | 28 | 2020 |
Failure of DNA double-strand break repair by tau mediates Alzheimer’s disease pathology in vitro M Asada-Utsugi, K Uemura, T Ayaki, M T. Uemura, S Minamiyama, ... Communications biology 5 (1), 358, 2022 | 25 | 2022 |
Expression and activity of thrombomodulin in human gingival epithelium: in vivo and in vitro studies T Matsuyama, Y Izumi, K Shibatate, Y Yotsumoto, H Obama, M Uemura, ... Journal of periodontal research 35 (3), 146-157, 2000 | 17 | 2000 |
Lewy Body Disease Primate Model with α‐Synuclein Propagation from the Olfactory Bulb M Sawamura, H Onoe, H Tsukada, K Isa, H Yamakado, S Okuda, M Ikuno, ... Movement Disorders 37 (10), 2033-2044, 2022 | 9 | 2022 |