Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein K Kondo, J Klco, E Nakamura, M Lechpammer, WG Kaelin Cancer cell 1 (3), 237-246, 2002 | 919 | 2002 |
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer S Lee, E Nakamura, H Yang, W Wei, MS Linggi, MP Sajan, RV Farese, ... Cancer cell 8 (2), 155-167, 2005 | 637 | 2005 |
4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer E Nakamura, M Sato, H Yang, F Miyagawa, M Harasaki, K Tomita, ... Journal of Biological Chemistry 274 (5), 3009-3016, 1999 | 365 | 1999 |
Hypoxia inducible factor activates the transforming growth factor-α/epidermal growth factor receptor growth stimulatory pathway in VHL-/-renal cell carcinoma cells L Gunaratnam, M Morley, A Franovic, N De Paulsen, K Mekhail, ... Journal of Biological Chemistry 278 (45), 44966-44974, 2003 | 283 | 2003 |
The bHLH gene Hes1 is essential for expansion of early T cell precursors K Tomita, M Hattori, E Nakamura, S Nakanishi, N Minato, R Kageyama Genes & development 13 (9), 1203-1210, 1999 | 273 | 1999 |
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, ... Nature communications 9 (1), 1685, 2018 | 254 | 2018 |
SLFN11 blocks stressed replication forks independently of ATR J Murai, SW Tang, E Leo, SA Baechler, CE Redon, H Zhang, M Al Abo, ... Molecular cell 69 (3), 371-384. e6, 2018 | 214 | 2018 |
Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient T Yoshida, H Kinoshita, T Segawa, E Nakamura, T Inoue, Y Shimizu, ... Cancer research 65 (21), 9611-9616, 2005 | 207 | 2005 |
SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer L Li, C Shen, E Nakamura, K Ando, S Signoretti, R Beroukhim, GS Cowley, ... Cancer cell 24 (6), 738-750, 2013 | 167 | 2013 |
Secreted CXCL1 is a potential mediator and marker of the tumor invasion of bladder cancer H Kawanishi, Y Matsui, M Ito, J Watanabe, T Takahashi, K Nishizawa, ... Clinical Cancer Research 14 (9), 2579-2587, 2008 | 126 | 2008 |
Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model N Terada, Y Shimizu, T Kamba, T Inoue, A Maeno, T Kobayashi, ... Cancer Research 70 (4), 1606-1615, 2010 | 117 | 2010 |
STAT3 Polymorphism Predicts Interferon-Alfa Response in Patients With Metastatic Renal Cell Carcinoma N Ito, M Eto, E Nakamura, A Takahashi, T Tsukamoto, H Toma, ... Journal of Clinical Oncology 25 (19), 2785-2791, 2007 | 115 | 2007 |
Impact of genetic variation in breast cancer resistance protein (BCRP/ABCG2) on sunitinib pharmacokinetics T Mizuno, M Fukudo, T Terada, T Kamba, E Nakamura, O Ogawa, K Inui, ... Drug metabolism and pharmacokinetics 27 (6), 631-639, 2012 | 113 | 2012 |
JunB promotes cell invasion and angiogenesis in VHL-defective renal cell carcinoma T Kanno, T Kamba, T Yamasaki, N Shibasaki, R Saito, N Terada, Y Toda, ... Oncogene 31 (25), 3098-3110, 2012 | 83 | 2012 |
Microarray-based identification of CUB-domain containing protein 1 as a potential prognostic marker in conventional renal cell carcinoma Y Awakura, E Nakamura, T Takahashi, H Kotani, Y Mikami, T Kadowaki, ... Journal of cancer research and clinical oncology 134, 1363-1369, 2008 | 76 | 2008 |
Verotoxin induces rapid elimination of human renal tumor xenografts in SCID mice S Ishitoya, H Kurazono, H Nishiyama, E Nakamura, T Kamoto, T Habuchi, ... The Journal of urology 171 (3), 1309-1313, 2004 | 75 | 2004 |
Clinical sequencing using a next‐generation sequencing‐based multiplex gene assay in patients with advanced solid tumors T Kou, M Kanai, Y Yamamoto, M Kamada, M Nakatsui, T Sakuma, ... Cancer science 108 (7), 1440-1446, 2017 | 73 | 2017 |
Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer R Saito, R Shirakawa, H Nishiyama, T Kobayashi, M Kawato, T Kanno, ... Oncogene 32 (7), 894-902, 2013 | 71 | 2013 |
Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein E Nakamura, P Abreu-e-Lima, Y Awakura, T Inoue, T Kamoto, O Ogawa, ... The American journal of pathology 168 (2), 574-584, 2006 | 71 | 2006 |
ABCG2 421C> A polymorphism and high exposure of sunitinib in a patient with renal cell carcinoma T Mizuno, T Terada, T Kamba, M Fukudo, T Katsura, E Nakamura, ... Annals of oncology 21 (6), 1382-1383, 2010 | 70 | 2010 |