| SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β SH Cho, JA Chen, F Sayed, ME Ward, F Gao, TA Nguyen, G Krabbe, ... Journal of Neuroscience 35 (2), 807-818, 2015 | 268 | 2015 |
| Targeting microglia for the treatment of Alzheimer's Disease PD Wes, FA Sayed, F Bard, L Gan Glia 64 (10), 1710-1732, 2016 | 192 | 2016 |
| Critical data‐based re‐evaluation of minocycline as a putative specific microglia inhibitor T Möller, F Bard, A Bhattacharya, K Biber, B Campbell, E Dale, C Eder, ... Glia 64 (10), 1788-1794, 2016 | 170 | 2016 |
| Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain L Zhan, G Krabbe, F Du, I Jones, MC Reichert, M Telpoukhovskaia, ... PLoS biology 17 (2), e3000134, 2019 | 143 | 2019 |
| Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy FA Sayed, M Telpoukhovskaia, L Kodama, Y Li, Y Zhou, D Le, A Hauduc, ... Proceedings of the National Academy of Sciences 115 (40), 10172-10177, 2018 | 135 | 2018 |
| Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia G Krabbe, SS Minami, JI Etchegaray, P Taneja, B Djukic, D Davalos, D Le, ... Proceedings of the National Academy of Sciences 114 (19), 5029-5034, 2017 | 119 | 2017 |
| Microglial microRNAs mediate sex-specific responses to tau pathology L Kodama, E Guzman, JI Etchegaray, Y Li, FA Sayed, L Zhou, Y Zhou, ... Nature neuroscience 23 (2), 167-171, 2020 | 87 | 2020 |
| AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation FA Sayed, L Kodama, L Fan, GK Carling, JC Udeochu, D Le, Q Li, L Zhou, ... Science Translational Medicine 13 (622), eabe3947, 2021 | 65 | 2021 |
| Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia MA Telpoukhovskaia, K Liu, FA Sayed, JI Etchegaray, M Xie, L Zhan, Y Li, ... Scientific reports 10 (1), 13688, 2020 | 19 | 2020 |
| TREM2 and amyloid beta: a love-hate relationship J Udeochu, FA Sayed, L Gan Neuron 97 (5), 991-993, 2018 | 19 | 2018 |
| Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models M Das, W Mao, Y Voskobiynyk, D Necula, I Lew, C Petersen, A Zahn, ... Neurobiology of disease 186, 106263, 2023 | 8 | 2023 |
| AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans FA Sayed, L Kodama, JC Udeochu, L Fan, GK Carling, D Le, Q Li, L Zhou, ... bioRxiv, 2020.07. 24.218719, 2020 | 5 | 2020 |
| F1‐07‐01: ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER'S DISEASE L Mucke, K Akassoglou, M Das, L Gan, K Ho, M Merlini, A Orr, VA Rafalski, ... Alzheimer's & Dementia 15, P188-P188, 2019 | | 2019 |
| P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING C Clelland, JI Etchegaray, L Kodama, F Sayed, A Sachdev, Y Li, D Le, ... Alzheimer's & Dementia 15, P1509-P1509, 2019 | | 2019 |
| Identifying compounds that restore normal cellular function in Frontotemporal dementia caused by progranulin haploinsufficiency M Telpoukhovskaia, K Liu, F Sayed, JI Etchegaray, Y Zhou, D Le, M Xie, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
