Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 235 | 2020 |
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir, Y Zhang, ... Cell 184 (18), 4784-4818. e17, 2021 | 191 | 2021 |
Bioactive Pyridine-N-oxide Disulfides from Allium stipitatum G O’Donnell, R Poeschl, O Zimhony, M Gunaratnam, JBC Moreira, ... Journal of Natural Products 72 (3), 360-365, 2009 | 118 | 2009 |
Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis JD Guzman, A Gupta, D Evangelopoulos, C Basavannacharya, LC Pabon, ... Journal of antimicrobial chemotherapy 65 (10), 2101-2107, 2010 | 103 | 2010 |
Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosis T Munshi, A Gupta, D Evangelopoulos, JD Guzman, S Gibbons, NH Keep, ... PloS one 8 (3), e60143, 2013 | 95 | 2013 |
Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay JD Guzman, D Evangelopoulos, A Gupta, K Birchall, S Mwaigwisya, ... BMJ open 3 (6), e002672, 2013 | 92 | 2013 |
A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus WKP Shiu, JP Malkinson, MM Rahman, J Curry, P Stapleton, ... International journal of antimicrobial agents 42 (6), 513-518, 2013 | 76 | 2013 |
An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis K Osman, D Evangelopoulos, C Basavannacharya, A Gupta, TD McHugh, ... International journal of antimicrobial agents 39 (2), 124-129, 2012 | 74 | 2012 |
Antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents J Zhao, D Evangelopoulos, S Bhakta, AI Gray, V Seidel Journal of Ethnopharmacology 155 (1), 796-800, 2014 | 72 | 2014 |
Rapid methods for testing inhibitors of mycobacterial growth D Evangelopoulos, S Bhakta Antibiotic Resistance Protocols: Second Edition, 193-201, 2010 | 69 | 2010 |
Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy I Honeyborne, TD McHugh, I Kuittinen, A Cichonska, D Evangelopoulos, ... BMC medicine 14, 1-13, 2016 | 63 | 2016 |
Repurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs A Maitra, S Bates, M Shaik, D Evangelopoulos, I Abubakar, TD McHugh, ... British medical bulletin 118 (1), 138, 2016 | 60 | 2016 |
2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosis JD Guzman, PN Mortazavi, T Munshi, D Evangelopoulos, TD McHugh, ... MedChemComm 5 (1), 47-50, 2014 | 56 | 2014 |
Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N′-((E)-3,7 … S Bhakta, N Scalacci, A Maitra, AK Brown, S Dasugari, D Evangelopoulos, ... Journal of Medicinal Chemistry 59 (6), 2780-2793, 2016 | 55 | 2016 |
Understanding anti-tuberculosis drug efficacy: rethinking bacterial populations and how we model them D Evangelopoulos, JD da Fonseca, SJ Waddell International Journal of Infectious Diseases 32, 76-80, 2015 | 54 | 2015 |
Arylamine N-acetyltransferases in mycobacteria E Sim, J Sandy, D Evangelopoulos, E Fullam, S Bhakta, I Westwood, ... Current Drug Metabolism 9 (6), 510-519, 2008 | 53 | 2008 |
Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis NA Lack, A Kawamura, E Fullam, N Laurieri, S Beard, AJ Russell, ... Biochemical Journal 418 (2), 369-378, 2009 | 49 | 2009 |
Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis molecular bacterial load assay W Sabiiti, K Azam, ECW Farmer, D Kuchaka, B Mtafya, R Bowness, ... Thorax 75 (7), 606-608, 2020 | 47 | 2020 |
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and … JD Guzman, A Wube, D Evangelopoulos, A Gupta, A Hüfner, ... Journal of antimicrobial chemotherapy 66 (8), 1766-1772, 2011 | 45 | 2011 |
Streptococcal dTDP‐L‐rhamnose biosynthesis enzymes: functional characterization and lead compound identification SL van der Beek, A Zorzoli, E Çanak, RN Chapman, K Lucas, BH Meyer, ... Molecular microbiology 111 (4), 951-964, 2019 | 43 | 2019 |