| A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis J Ollinger, MA Bailey, GC Moraski, A Casey, S Florio, T Alling, MJ Miller, ... PloS one 8 (4), e60531, 2013 | 177 | 2013 |
| Advancement of Imidazo[1,2-a]pyridines with Improved Pharmacokinetics and nM Activity vs. Mycobacterium tuberculosis GC Moraski, LD Markley, J Cramer, PA Hipskind, H Boshoff, MA Bailey, ... ACS medicinal chemistry letters 4 (7), 675-679, 2013 | 118 | 2013 |
| Synthesis and evaluation of the 2-aminothiazoles as anti-tubercular agents EA Kesicki, MA Bailey, Y Ovechkina, JV Early, T Alling, J Bowman, ... PLoS One 11 (5), e0155209, 2016 | 62 | 2016 |
| Putting tuberculosis (TB) to rest: transformation of the sleep aid, Ambien, and “anagrams” generated potent antituberculosis agents GC Moraski, PA Miller, MA Bailey, J Ollinger, T Parish, HI Boshoff, S Cho, ... ACS Infectious Diseases 1 (2), 85-90, 2015 | 55 | 2015 |
| Identification of phenoxyalkylbenzimidazoles with antitubercular activity NS Chandrasekera, T Alling, MA Bailey, M Files, JV Early, J Ollinger, ... Journal of medicinal chemistry 58 (18), 7273-7285, 2015 | 43 | 2015 |
| Application of locked nucleic acid oligonucleotides for siRNA preclinical bioanalytics MB Thayer, JM Lade, D Doherty, F Xie, B Basiri, OS Barnaby, NS Bala, ... Scientific Reports 9 (1), 3566, 2019 | 41 | 2019 |
| Synthesis and evaluation of the 2, 4-diaminoquinazoline series as anti-tubercular agents J Odingo, T O’Malley, EA Kesicki, T Alling, MA Bailey, J Early, J Ollinger, ... Bioorganic & Medicinal Chemistry 22 (24), 6965-6979, 2014 | 33 | 2014 |
| Oxadiazoles have butyrate-specific conditional activity against Mycobacterium tuberculosis JV Early, A Casey, MA Martinez-Grau, IC Gonzalez Valcarcel, M Vieth, ... Antimicrobial agents and chemotherapy 60 (6), 3608-3616, 2016 | 30 | 2016 |
| A high-throughput whole cell screen to identify inhibitors of Mycobacterium tuberculosis J Ollinger, A Kumar, DM Roberts, MA Bailey, A Casey, T Parish PLoS One 14 (1), e0205479, 2019 | 28 | 2019 |
| Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives D Kumar, KK Raj, MA Bailey, T Alling, T Parish, DS Rawat Bioorganic & medicinal chemistry letters 23 (5), 1365-1369, 2013 | 25 | 2013 |
| In Vitro Evaluation of Novel Nitazoxanide Derivatives against Mycobacterium tuberculosis J Odingo, MA Bailey, M Files, JV Early, T Alling, D Dennison, J Bowman, ... ACS omega 2 (9), 5873-5890, 2017 | 22 | 2017 |
| Nitazoxanide is active against Mycobacterium leprae MA Bailey, H Na, MS Duthie, TP Gillis, R Lahiri, T Parish PLoS One 12 (8), e0184107, 2017 | 21 | 2017 |
| Plasma and liver protein binding of N-acetylgalactosamine–conjugated small interfering RNA SC Humphreys, MB Thayer, JM Lade, B Wu, K Sham, B Basiri, Y Hao, ... Drug Metabolism and Disposition 47 (10), 1174-1182, 2019 | 19 | 2019 |
| 8‐Hydroxyquinolines are bactericidal against Mycobacterium tuberculosis JO Odingo, JV Early, J Smith, J Johnson, MA Bailey, M Files, J Guzman, ... Drug Development Research 80 (5), 566-572, 2019 | 19 | 2019 |
| Optimization and Evaluation of 5‐Styryl‐Oxathiazol‐2‐one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents F Russo, J Gising, L Åkerbladh, AK Roos, A Naworyta, SL Mowbray, ... ChemistryOpen 4 (3), 342-362, 2015 | 18 | 2015 |
| Emerging siRNA design principles and consequences for biotransformation and disposition in drug development SC Humphreys, MB Thayer, J Campbell, WLK Chen, D Adams, JM Lade, ... Journal of Medicinal Chemistry 63 (12), 6407-6422, 2020 | 17 | 2020 |
| Iodine-Mediated Multicomponent Synthesis of 3-Sulfenylimidazo [1, 2-a] pyridines from 2-Aminopyridines, Ketones, and Sulfonyl Hydrazides S Hu, S Du, Y Yao, Z Yang, H Ren, Z Chen Synlett 30 (05), 625-629, 2019 | 17 | 2019 |
| Quantification of siRNA-antibody conjugates in biological matrices by triplex-forming oligonucleotide ELISA SC Humphreys, MB Thayer, IDG Campuzano, C Netirojjanakul, BM Rock nucleic acid therapeutics 29 (3), 161-166, 2019 | 16 | 2019 |
| POE immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices MB Thayer, SC Humphreys, KS Chung, JM Lade, KD Cook, BM Rock Scientific Reports 10 (1), 10425, 2020 | 14 | 2020 |
| Introducing an in vitro liver stability assay capable of predicting the in vivo pharmacodynamic efficacy of siRNAs for IVIVC B Basiri, F Xie, B Wu, SC Humphreys, JM Lade, MB Thayer, P Yamaguchi, ... Molecular Therapy-Nucleic Acids 21, 725-736, 2020 | 13 | 2020 |
Tanya ParishSeattle Children's Hospital在 seattlechildrens.org 的电子邮件经过验证
