Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. RO Williams, M Feldmann, RN Maini Proceedings of the National Academy of Sciences 89 (20), 9784-9788, 1992 | 1359 | 1992 |
Specificity of T lymphocyte cytotoxicity to autologous hepatocytes in chronic hepatitis B virus infection: evidence that T cells are directed against HBV core antigen expressed … M Mondelli, GM Vergani, A Alberti, D Vergani, B Portmann, AL Eddleston, ... Journal of immunology (Baltimore, Md.: 1950) 129 (6), 2773-2778, 1982 | 459 | 1982 |
Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen‐induced arthritis C Mauri, RO Williams, M Walmsley, M Feldmann European journal of immunology 26 (7), 1511-1518, 1996 | 396 | 1996 |
Interleukin‐10 inhibition of the progression of established collagen‐induced arthritis M Walmsley, PD Katsikis, E Abney, S Parry, RO Williams, RN Maini, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1996 | 341 | 1996 |
Monoclonal anti-TNF alpha antibody as a probe of pathogenesis and therapy of rheumatoid disease. RN Maini, MJ Elliott, FM Brennan, RO Williams, CQ Chu, EWA Paleolog, ... Immunological reviews 144, 195-223, 1995 | 277 | 1995 |
RHAMM, a receptor for hyaluronan-mediated motility, compensates for CD44 in inflamed CD44-knockout mice: a different interpretation of redundancy S Nedvetzki, E Gonen, N Assayag, R Reich, RO Williams, RL Thurmond, ... Proceedings of the National Academy of Sciences 101 (52), 18081-18086, 2004 | 274 | 2004 |
Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis. RO Williams, LJ Mason, M Feldmann, RN Maini Proceedings of the National Academy of Sciences 91 (7), 2762-2766, 1994 | 256 | 1994 |
IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production K Blazek, HL Eames, M Weiss, AJ Byrne, D Perocheau, JE Pease, ... Journal of Experimental Medicine 212 (6), 845-853, 2015 | 244 | 2015 |
Safety cryotherapy catheter TD Holland, J Joye, R Williams, R Williams US Patent 6,811,550, 2004 | 240 | 2004 |
Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells CA Notley, JJ Inglis, S Alzabin, FE McCann, KE McNamee, RO Williams The Journal of experimental medicine 205 (11), 2491-2497, 2008 | 235 | 2008 |
Protocol for the induction of arthritis in C57BL/6 mice JJ Inglis, E Šimelyte, FE McCann, G Criado, RO Williams Nature protocols 3 (4), 612-618, 2008 | 205 | 2008 |
Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll‐like receptors S Sacre, M Medghalchi, B Gregory, F Brennan, R Williams Arthritis & Rheumatism 62 (3), 683-693, 2010 | 201 | 2010 |
Tumour necrosis factor α is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis RP Mookerjee, S Sen, NA Davies, SJ Hodges, R Williams, R Jalan Gut 52 (8), 1182-1187, 2003 | 201 | 2003 |
The determination of an immunologically active dose of interferon-gamma in patients with melanoma. AE Maluish, WJ Urba, DL Longo, WR Overton, D Coggin, ER Crisp, ... Journal of Clinical Oncology 6 (3), 434-445, 1988 | 197 | 1988 |
Suppression of collagen-induced arthritis by continuous administration of IL-4. AC Horsfall, DM Butler, L Marinova, PJ Warden, RO Williams, RN Maini, ... Journal of immunology (Baltimore, Md.: 1950) 159 (11), 5687-5696, 1997 | 195 | 1997 |
Collagen‐induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade JJ Inglis, CA Notley, D Essex, AW Wilson, M Feldmann, P Anand, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 190 | 2007 |
Inflammation is preceded by tumor necrosis factor‐dependent infiltration of mesenchymal cells in experimental arthritis L Marinova‐Mutafchieva, RO Williams, K Funa, RN Maini, NJ Zvaifler Arthritis & Rheumatism 46 (2), 507-513, 2002 | 184 | 2002 |
Treg cell function in rheumatoid arthritis is compromised by CTLA‐4 promoter methylation resulting in a failure to activate the indoleamine 2, 3‐dioxygenase pathway AP Cribbs, A Kennedy, H Penn, JE Read, P Amjadi, P Green, K Syed, ... Arthritis & rheumatology 66 (9), 2344-2354, 2014 | 167 | 2014 |
Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway S Alzabin, SM Abraham, TE Taher, A Palfreeman, D Hull, K McNamee, ... Annals of the rheumatic diseases 71 (10), 1741-1748, 2012 | 166 | 2012 |
Amelioration of collagen‐induced arthritis and suppression of interferon‐γ, interleukin‐12, and tumor necrosis factor α production by interferon‐β gene therapy KA Triantaphyllopoulos, RO Williams, H Tailor, Y Chernajovsky Arthritis & Rheumatism: Official Journal of the American College of …, 1999 | 166 | 1999 |